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Characterization and protein engineering of glycosyltransferases for the biosynthesis of diverse hepatoprotective cycloartane-type saponins in Astragalus membranaceus 期刊论文
PLANT BIOTECHNOLOGY JOURNAL, 2023
作者:  Chen,Kuan;  Zhang,Meng;  Gao,Baihan;  Hasan,Aobulikasimu;  Li,Junhao;  Bao,Yang'oujie;  Fan,Jingjing;  Yu,Rong;  Yi,Yang;  Agren,Hans;  Wang,Zilong;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
浏览  |  Adobe PDF(5002Kb)  |  收藏  |  浏览/下载：88/26  |  提交时间：2024/05/09
astragalosides  biosynthesis  glycosyltransferases  protein engineering  Astragalus membranaceus  FUNCTIONAL-CHARACTERIZATION  UDP-GLYCOSYLTRANSFERASES  CARBON-TETRACHLORIDE  PROTOPANAXATRIOL  PHARMACOLOGY  GENERATION  CHEMISTRY  ACCURACY  PATHWAY  
重楼属中富含偏诺甾体皂苷的植物资源挖掘及其研究 学位论文
: 中国科学院大学, 2022
作者:  余玲玲
Adobe PDF(11095Kb)  |  收藏  |  浏览/下载：40/0  |  提交时间：2024/05/14
重楼属 (Paris L.)，黑药花科，偏诺皂苷，球药隔重楼，LC-MS/MS，诱导血小板聚集活性  Paris L., Melanthiaceae, Pennogenin saponins, Paris fargesii, LC-MS/MS, Inducing platelet aggregation activity  
Immunostimulatory 6/6/6/6 Tetracyclic Triterpenoid Saponins with the Methyl-30 Incorporated Cyclization from the Root of Colquhounia elegans 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 19, 页码: 7462-7466
作者:  Hua,Juan;  Liu,Yan-Chun;  Luo,Shi-Hong;  Liu,Yan;  Xiao,Chao-Jiang;  Li,Xiao-Nian;  Li,Sheng-Hong
浏览  |  Adobe PDF(1899Kb)  |  收藏  |  浏览/下载：147/46  |  提交时间：2022/04/02
QUILLAJA-SAPONARIA  BIOSYNTHESIS  MECHANISMS  ADJUVANTS  VARIANTS  PRODUCTS  CYCLASE  
Biochemical and Metabolic Insights into Hyoscyamine Dehydrogenase 期刊论文
ACS CATALYSIS, 2021, 卷号: 11, 期号: 5, 页码: 2912-2924
作者:  Qiu,Fei;  Yan,Yijun;  Zeng,Junlan;  Huang,Jian-Ping;  Zeng,Lingjiang;  Zhong,Wei;  Lan,Xiaozhong;  Chen,Min;  Huang,Sheng-Xiong;  Liao,Zhihua
Adobe PDF(4893Kb)  |  收藏  |  浏览/下载：120/23  |  提交时间：2022/04/02
biosynthesis  crystal structure  hyoscyamine  hyoscyamine dehydrogenase  metabolic engineering  TROPANE ALKALOID BIOSYNTHESIS  TRANSGENIC ATROPA-BELLADONNA  POLYKETIDE SYNTHASE  ROOT CULTURES  SCOPOLAMINE  PUTRESCINE  PLANTS  6-BETA-HYDROXYLASE  CYTOCHROME-P450  PATHWAY  
Phytochemicals from the Leaves of Cyclocarya paliurus and their 11 beta-HSD1 Enzyme Inhibitory Effects 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 卷号: 18, 期号: 1
作者:  Yan,Huan;  Li,Xiang;  Ni,Wei;  Zhao,Qing;  Leng,Ying;  Liu,Hai-Yang
浏览  |  Adobe PDF(1714Kb)  |  收藏  |  浏览/下载：116/37  |  提交时间：2022/04/02
Cyclocarya paliurus  dammarane-type triterpenoid saponins  11β  -HSD1 enzyme  inhibitory activity  ANTIOXIDANT ACTIVITIES  CHEMICAL-CONSTITUENTS  DEHYDROGENASE TYPE-1  TRITERPENOIDS  POLYSACCHARIDE  SAPONINS  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2630Kb)  |  收藏  |  浏览/下载：194/92  |  提交时间：2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
A One-Pot Synthesis of Glycans and Nucleosides Based on ortho-(1-Phenylvinyl)benzyl Glycosides 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 21, 页码: 8257-8261
作者:  Yang,Rui;  He,Haiqing;  Chen,Zixi;  Huang,Yingying;  Xiao,Guozhi
浏览  |  Adobe PDF(1646Kb)  |  收藏  |  浏览/下载：104/25  |  提交时间：2022/04/02
LATENT THIOGLYCOSYL DONORS  CHEMICAL-SYNTHESIS  BIOLOGICAL ROLES  GLYCOSYLATION  OLIGOSACCHARIDE  CANCER  ALKYNYLBENZOATES  CHEMISTRY  VERSATILE  ANALOGS  
Previously undescribed pyridyl-steroidal glycoalkaloids and 23S,26R-hydroxylated spirostanoid saponin from the fruits of Solanum violaceum ortega and their bioactivities 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 184, 页码: 112656
作者:  Kaunda,Joseph Sakah;  Qin,Xu-Jie;  Zhu,Hong-Tao;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
浏览  |  Adobe PDF(2247Kb)  |  收藏  |  浏览/下载：209/34  |  提交时间：2022/04/02
Solanum violaceum  Solanaceae  Glycoalkaloids  Solanindiosides A-C  235,26R-hydroxylated spirostanoid saponin  Lignans  Cytotoxicity  Apoptosis  Antibacterial  Staphylococcus aureus  
广西莪术、团花、角茴香的化学成分及抗炎镇痛活性研究 学位论文
, 2020
作者:  袁海恋
Adobe PDF(5757Kb)  |  收藏  |  浏览/下载：65/1  |  提交时间：2023/11/02
岩藻糖化糖胺聚糖的寡糖结构及其抗乙酰肝素酶活性研究 学位论文
, 2020
作者:  周路坦
Adobe PDF(10399Kb)  |  收藏  |  浏览/下载：103/0  |  提交时间：2023/11/02