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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
作者:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  收藏  |  浏览/下载:199/1  |  提交时间:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
作者:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  收藏  |  浏览/下载:323/1  |  提交时间:2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
新型天然铁死亡诱导剂的筛选及作用机制研究 学位论文
: 中国科学院大学, 2022
作者:  赵越勤
Adobe PDF(5494Kb)  |  收藏  |  浏览/下载:18/0  |  提交时间:2024/05/14
肿瘤,天然产物,铁死亡,溶酶体,p53  Cancer, Nature products, Ferroptosis, Lysosome, p53  
Design and synthesis of ludartin derivatives as potential anticancer agents against hepatocellular carcinoma 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 7, 页码: 1224-1239
作者:  Sun, Jin-Jin;  Wang, Jin-Ping;  Li, Tian-Ze;  Ma, Yun-Bao;  Xue, Dong;  Chen, Ji-Jun
Adobe PDF(1092Kb)  |  收藏  |  浏览/下载:27/5  |  提交时间:2024/04/30
Ludartin derivatives  Antihepatoma activity  HepG2 cells  Huh7 cells  SESQUITERPENE LACTONES  CHEMICAL-CONSTITUENTS  GUAIANOLIDES  ANTITUMOR  ANALOGS  
分子模拟应用于岩藻糖化糖胺聚糖 3D 结构确定及其与内源 性因子 X 酶的相互作用模式考察 学位论文
, 2021
作者:  陈鼎元
Adobe PDF(4948Kb)  |  收藏  |  浏览/下载:75/0  |  提交时间:2023/11/02
非洲马铃果中微量MIAs的研究及tabersonine的结构修饰 学位论文
, 2021
作者:  赵倩
Adobe PDF(8002Kb)  |  收藏  |  浏览/下载:17/0  |  提交时间:2024/03/20
Steroidal saponins with cytotoxic effects from the rhizomes of Asparagus cochinchinensis 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 105237
作者:  Liu,Bo;  Li,Bingxin;  Zhou,Di;  Wen,Xiaoyan;  Wang,Yajun;  Chen,Gang;  Li,Ning
收藏  |  浏览/下载:64/0  |  提交时间:2022/04/02
Asparagus cochinchinensis  Steroidal  NCI-H460 cell line  Cytotoxic  Apoptosis  GLYCOSIDES  CELL  CANCER  
Reviewing the world's edible mushroom species: A new evidence-based classification system 期刊论文
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, 2021
作者:  Li,Huili;  Tian,Yang;  Menolli Jr,Nelson;  Ye,Lei;  Karunarathna,Samantha C.;  Perez-Moreno,Jesus;  Rahman,Mohammad Mahmudur;  Rashid,Md Harunur;  Phengsintham,Pheng;  Rizal,Leela;  Kasuya,Taiga;  Lim,Young Woon;  Dutta,Arun Kumar;  Khalid,Abdul Nasir;  Le Thanh Huyen;  Balolong,Marilen Parungao;  Baruah,Gautam;  Madawala,Sumedha;  Thongklang,Naritsada;  Hyde,Kevin D.;  Kirk,Paul M.;  Xu,Jianchu;  Sheng,Jun;  Boa,Eric;  Mortimer,Peter E.
Adobe PDF(1089Kb)  |  收藏  |  浏览/下载:165/60  |  提交时间:2023/09/08
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
作者:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
Adobe PDF(2120Kb)  |  收藏  |  浏览/下载:202/47  |  提交时间:2022/04/02
Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1648-1666
作者:  Su,Lihua;  Zhang,Xintian;  Ma,Yunbao;  Geng,Changan;  Huang,Xiaoyan;  Hu,Jing;  Li,Tianze;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xuemei;  Chen,Ji-Jun
Adobe PDF(4074Kb)  |  收藏  |  浏览/下载:109/40  |  提交时间:2022/04/02
Guaianolide dimers  Artematrolides AeR  Artemisia atrovirens  Cytotoxicity  Cell cycle  Apoptosis  FARNESYL-PROTEIN TRANSFERASE  CELL-CYCLE ARREST  HEPATOCELLULAR-CARCINOMA  GUAIANOLIDES  LACTONES  INHIBITORS  ARTEMINOLIDE  APOPTOSIS  ARGYI  HELA