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Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
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Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
作者:  Chen, Si-Yue;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Yang, Xiao-Tong;  Su, Li-Hua;  He, Xiao-Feng;  Li, Tian-Ze;  Deng, Zhen-Tao;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Gastrodia elata  Polybenzyls  Melatonin receptors  Structure-activity relationships  Docking study  
Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 228-235
作者:  Yang, Tong-Hua;  Yan, De-Xiu;  Huang, Xiao-Yan;  Hou, Bo;  Ma, Yun-Bao;  Peng, Hua;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Geng, Chang-An
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Terminthia paniculata (Wall. ex G. Don) CY Wu & TL Ming  Anacardiaceae  Termipaniculatones A-F  Chalcone-flavonone heterodimers  Xanthine oxidase inhibitors  Anti-gout potency  
Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 39-46
作者:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Uncaria rhynchophylla  Catechin  Melatonin receptors  Metabolites  Antidepressant activity  
Structural Revision of Macropodumine A and Structure of 2-Deoxymacropodumine A, Daphniphyllum Alkaloids with 11-Membered Macrolactone Rings 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 3, 页码: 427-430
作者:  Zhang, Jiahui;  Cao, Pei;  Ma, Yuanliang;  Fang, Xin;  Yang, Jing;  Zhang, Yu;  Chen, Duozhi;  Gu, Yucheng;  Di, Yingtong;  Hao, Xiaojiang
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Bioassay-guided isolation of saikosaponins with agonistic activity on 5-hydroxytryptamine 2C receptor from Bupleurum chinense and their potential use for the treatment of obesity 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 6, 页码: 467-473
作者:  Sun Chang-Li;  Geng Chang-An;  Huang Xiao-Yan;  Ma Yun-Bao;  Zheng Xiao-Hong;  Yang Tong-Hua;  Chen Xing-Long;  Yin Xiu-Juan;  Zhang Xue-Mei;  Chen Ji-Jun
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Bupleurum Chinense  5-hydroxytryptamine 2c (5-ht2c) Receptor  Anti-obesity  Saikosaponins  
Catalytic Asymmetric Total Synthesis of (+)- and (-)-Paeoveitol via a Hetero-Diels-Alder Reaction 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 3, 页码: 429-431
作者:  Li,Tian-Ze;  Geng,Chang-An;  Yin,Xiu-Juan;  Yang,Tong-Hua;  Chen,Xing-Long;  Huang,Xiao-Yan;  Ma,Yun-Bao;  Zhang,Xue-Mei;  Chen,Ji-Jun
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Ortho-quinone Methides  Paeonia-veitchii  Natural-products  Paeoveitol  
Bioactivity-guided synthesis of gramine derivatives as new MT1 and 5-HT1A receptors agonists 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 卷号: 19, 期号: 6, 页码: 610-622
作者:  Yin, Xiu-Juan;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Geng, Chang-An;  Li, Tian-Ze;  Chen, Xing-Long;  Yang, Tong-Hua;  Zhou, Jun;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Gramine  Melatonin Receptor  5-hydroxy-tryptamine Receptor  Agonistic Activity  Structure-activity Relationships  
Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata 期刊论文
PHYTOCHEMISTRY LETTERS, 2016, 卷号: 18, 期号: 1, 页码: 176-179
作者:  Yuan, Wen-Juan;  Yang, Guo-Ping;  Zhang, Jia-Hui;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Di, Ying-Tong;  Hao, Xiao-Jiang
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Euphorbiaceae  Euphorbia Ebracteolata  Diterpenes  Ebracteolatas A-c  Cytotoxic Activity  
16-nor Limonoids from Harrisonia perforata as promising selective 11 beta-HSD1 inhibitors 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 1
作者:  Xiao-HuiYan;  Yi, Ping;  Cao, Pei;  Yang, Shi-Ying;  Fang, Xin;  Zhang, Yu;  Wu, Bin;  Leng, Ying;  Di, Ying-Tong;  Lv, Yang;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1151Kb)  |  收藏  |  浏览/下载：354/57  |  提交时间：2017/01/05