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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：296/66  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
SJP-L-5 inhibits HIV-1 polypurine tract primed plus-strand DNA elongation, indicating viral DNA synthesis initiation at multiple sites under drug pressure 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 期号: 1, 页码: 2574
作者:  Zhang, Xing-Jie;  Wang, Rui-Rui;  Chen, Huan;  Luo, Rong-Hua;  Yang, Liu-Meng;  Liu, Jing-Ping;  Sun, Han-Dong;  Zhang, Hong-Bin;  Xiao, Wei-Lie;  Zheng, Yong-Tang
浏览  |  Adobe PDF(2175Kb)  |  收藏  |  浏览/下载：378/27  |  提交时间：2018/05/08
Bioactive ent-kaurane diterpenoids from Isodon rubescens 期刊论文
PHYTOCHEMISTRY, 2017, 卷号: 143, 页码: 199-207
作者:  Zhang, Yuan-Yuan;  Jiang, Hua-Yi;  Liu, Miao;  Hu, Kun;  Wang, Wei-Guang;  Du, Xue;  Li, Xiao-Nian;  Pu, Jian-Xin;  Sun, Han-Dong
浏览  |  Adobe PDF(1170Kb)  |  收藏  |  浏览/下载：418/64  |  提交时间：2017/11/20
Isodon Rubescens  Lamiaceae  Cytotoxicity  7  Anti-inflammatory  20-epoxy-ent-kaurane Diterpenoids  
Gypmacrophin A, a Rare Pentacyclic Sesterterpenoid, Together with Three Depsides, Functioned as New Chemical Evidence for Gypsoplaca macrophylla (Zahlbr.) Timdal Identification 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 10, 页码: 1675
作者:  Zhou, Yuan-Fei;  Shi, Hai-Xia;  Hu, Kun;  Tang, Jian-Wei;  Li, Xing-Ren;  Du, Xue;  Sun, Han-Dong;  Wang, Li-Song;  Pu, Jian-Xin
浏览  |  Adobe PDF(573Kb)  |  收藏  |  浏览/下载：335/66  |  提交时间：2017/11/20
Gypsoplacaceae  Gypsoplaca Macrophylla  Sesterterpenoid  Identification  
Dibenzocyclooctadiene lignans from Kadsura heteroclita 期刊论文
FITOTERAPIA, 2017, 卷号: 119, 页码: 150-157
作者:  Luo, Yuan-Qing;  Liu, Miao;  Wen, Jin;  Wang, Wei-Guang;  Hu, Kun;  Li, Xiao-Nian;  Du, Xue;  Pu, Jian-Xin;  Sun, Han-Dong
Adobe PDF(684Kb)  |  收藏  |  浏览/下载：267/110  |  提交时间：2017/07/31
Kadsura Heteroclita  Dibenzocyclooctadiene Lignans  Cytotoxicity  
Efficient Semisynthesis of (-)-Pseudoirroratin A from (-)-Flexicaulin A and Assessment of Their Antitumor Activities 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 3, 页码: 372-376
作者:  Guo, Lei;  Tsang, Siu Wai;  Zhang, Tong-Xin;  Liu, Kang-Lun;  Guan, Yi-Fu;  Wang, Bo;  Sun, Han-Dong;  Zhang, Hong-Jie;  Wong, Man Shing
Adobe PDF(1840Kb)  |  收藏  |  浏览/下载：221/40  |  提交时间：2017/05/19
(-)-pseudoirroratin a  (-)-flexicaulin a  Apoptosis  Antitumor Activity  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：447/205  |  提交时间：2017/02/28
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
Adobe PDF(13632Kb)  |  收藏  |  浏览/下载：297/33  |  提交时间：2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Bioactive ent-kaurane diterpenoids from Isodon serra 期刊论文
PHYTOCHEMISTRY, 2016, 卷号: 130, 页码: 244-251
作者:  Wan, Jun;  Liu, Miao;  Jiang, Hua-Yi;  Yang, Jin;  Du, Xue;  Li, Xiao-Nian;  Wang, Wei-Guang;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
Adobe PDF(653Kb)  |  收藏  |  浏览/下载：463/79  |  提交时间：2016/11/04
Isodon Serra  Lamiaceae  Cytotoxic Activity  7  Anti-inflammatory  20-epoxy-ent-kaurane Diterpenoids  
Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae) 期刊论文
JOURNAL OF NATURAL MEDICINES, 2016, 卷号: 70, 期号: 2, 页码: 241-252
作者:  Kurimoto, Shin-ichiro;  Pu, Jian-Xin;  Sun, Han-Dong;  Shibata, Hirofumi;  Takaishi, Yoshihisa;  Kashiwada, Yoshiki
Adobe PDF(786Kb)  |  收藏  |  浏览/下载：285/65  |  提交时间：2016/06/27
Scutellaria Coleifolia  Lamiaceae  Diterpenoid  Neo-clerodane