Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae)
Kurimoto, Shin-ichiro1,3; Pu, Jian-Xin2; Sun, Han-Dong2; Shibata, Hirofumi1; Takaishi, Yoshihisa1; Kashiwada, Yoshiki1
2016-04-01
Source PublicationJOURNAL OF NATURAL MEDICINES
Volume70Issue:2Pages:241-252
AbstractTwenty new neo-clerodane type diterpenoids, scutefolides G(1)-S (1-20), were isolated from the 70 % aqueous acetone extract of the aerial parts of Scutellaria coleifolia. Their structures were elucidated by extensive spectroscopic analyses. The absolute configurations of 1, 2, 7, 8, 14 and 15 were determined by means of the CD exciton chirality method. Compounds 1, 2, 5, 7, 8, 12, 14, 15, 18 and 19 were evaluated for their cytotoxic activities against four human cancer cell lines, and anti-bacterial activities against methicillin-resistant Staphylococcus aureus.
KeywordScutellaria Coleifolia Lamiaceae Diterpenoid Neo-clerodane
DOI10.1007/s11418-016-0967-3
Indexed BySCI
Language英语
WOS IDWOS:000370365700013
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/25975
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Univ Tokushima, Grad Sch Pharmaceut Sci, 1-78 Shomachi, Tokushima 7708505, Japan
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
3.Himeji Dokkyo Univ, Fac Pharmaceut Sci, 7-2-1 Kamiohno, Himeji, Hyogo 6708524, Japan
Recommended Citation
GB/T 7714
Kurimoto, Shin-ichiro,Pu, Jian-Xin,Sun, Han-Dong,et al. Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae)[J]. JOURNAL OF NATURAL MEDICINES,2016,70(2):241-252.
APA Kurimoto, Shin-ichiro,Pu, Jian-Xin,Sun, Han-Dong,Shibata, Hirofumi,Takaishi, Yoshihisa,&Kashiwada, Yoshiki.(2016).Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae).JOURNAL OF NATURAL MEDICINES,70(2),241-252.
MLA Kurimoto, Shin-ichiro,et al."Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae)".JOURNAL OF NATURAL MEDICINES 70.2(2016):241-252.
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