Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae) | |
Kurimoto, Shin-ichiro1,3; Pu, Jian-Xin2; Sun, Han-Dong2; Shibata, Hirofumi1; Takaishi, Yoshihisa1; Kashiwada, Yoshiki1 | |
2016-04-01 | |
发表期刊 | JOURNAL OF NATURAL MEDICINES |
卷号 | 70期号:2页码:241-252 |
摘要 | Twenty new neo-clerodane type diterpenoids, scutefolides G(1)-S (1-20), were isolated from the 70 % aqueous acetone extract of the aerial parts of Scutellaria coleifolia. Their structures were elucidated by extensive spectroscopic analyses. The absolute configurations of 1, 2, 7, 8, 14 and 15 were determined by means of the CD exciton chirality method. Compounds 1, 2, 5, 7, 8, 12, 14, 15, 18 and 19 were evaluated for their cytotoxic activities against four human cancer cell lines, and anti-bacterial activities against methicillin-resistant Staphylococcus aureus. |
关键词 | Scutellaria Coleifolia Lamiaceae Diterpenoid Neo-clerodane |
DOI | 10.1007/s11418-016-0967-3 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000370365700013 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/25975 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Univ Tokushima, Grad Sch Pharmaceut Sci, 1-78 Shomachi, Tokushima 7708505, Japan 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 3.Himeji Dokkyo Univ, Fac Pharmaceut Sci, 7-2-1 Kamiohno, Himeji, Hyogo 6708524, Japan |
推荐引用方式 GB/T 7714 | Kurimoto, Shin-ichiro,Pu, Jian-Xin,Sun, Han-Dong,et al. Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae)[J]. JOURNAL OF NATURAL MEDICINES,2016,70(2):241-252. |
APA | Kurimoto, Shin-ichiro,Pu, Jian-Xin,Sun, Han-Dong,Shibata, Hirofumi,Takaishi, Yoshihisa,&Kashiwada, Yoshiki.(2016).Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae).JOURNAL OF NATURAL MEDICINES,70(2),241-252. |
MLA | Kurimoto, Shin-ichiro,et al."Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae)".JOURNAL OF NATURAL MEDICINES 70.2(2016):241-252. |
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