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Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
作者:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
Adobe PDF(4714Kb)  |  收藏  |  浏览/下载：322/42  |  提交时间：2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Nonasaccharide Inhibits Intrinsic Factor Xase Complex by Binding to Factor IXa and Disrupting Factor IXa-Factor VIIIa Interactions 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 期号: 5, 页码: 705-715
作者:  Xiao, Chuang;  Zhao, Longyan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
Adobe PDF(740Kb)  |  收藏  |  浏览/下载：236/61  |  提交时间：2019/06/24
nonasaccharide from fucosylated glycosaminoglycan  intrinsic factor Xase complex  factor IXa  anticoagulant  
Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 13
作者:  Guan, Ruowei;  Peng, Yuan;  Zhou, Lutan;  Zheng, Wenqi;  Liu, Xixi;  Wang, Pin;  Yuan, Qingxia;  Gao, Na;  Zhao, Longyan;  Zhao, Jinhua
浏览  |  Adobe PDF(2313Kb)  |  收藏  |  浏览/下载：165/6  |  提交时间：2019/06/24
Apostichopus japonicus  fucosylated glycosaminoglycan  oligosaccharide  unambiguous structure  anti-Fxase  
Synthesis of trisaccharide repeating unit of fucosylated chondroitin sulfate 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 卷号: 17, 期号: 11, 页码: 2877-2882
作者:  He, Haiqing;  Chen, Dong;  Li, Xiaomei;  Li, Chengji;  Zhao, Jin-Hua;  Qin, Hong-Bo
浏览  |  Adobe PDF(466Kb)  |  收藏  |  浏览/下载：271/47  |  提交时间：2019/04/15
Synthesis of Fucosylated Chondroitin Sulfate Nonasaccharide as a Novel Anticoagulant Targeting Intrinsic Factor Xase Complex 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 39, 页码: 12880-12885
作者:  Zhang, Xiao;  Liu, Huiying;  Lin, Lisha;  Yao, Wang;  Zhao, Jinhua;  Wu, Mingyi;  Li, Zhongjun
浏览  |  Adobe PDF(1568Kb)  |  收藏  |  浏览/下载：211/52  |  提交时间：2018/10/22
Anticoagulants  Drug Discovery  Fucosylated Chondroitin Sulfate  Glycosaminoglycans  Oligosaccharides  
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
作者:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(1313Kb)  |  收藏  |  浏览/下载：216/31  |  提交时间：2018/10/07
Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis  
Structural analysis and anticoagulant activities of three highly regular fucan sulfates as novel intrinsic factor Xase inhibitors 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 195, 页码: 257-266
作者:  Shang, Feineng;  Mou, Rongrong;  Zhang, Zhidong;  Gao, Na;  Lin, Lisha;  Li, Zhongkun;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(2021Kb)  |  收藏  |  浏览/下载：336/62  |  提交时间：2018/07/16
Fucan Sulfate  Chemical Structure  Anticoagulant  Polysaccharide  Sea Cucumber  
Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 423-435
作者:  Shang, Feineng;  Gao, Na;  Yin, Ronghua;  Lin, Lisha;  Xiao, Chuang;  Zhou, Lutan;  Li, Zi;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(3117Kb)  |  收藏  |  浏览/下载：252/74  |  提交时间：2018/05/08
Glycosaminoglycan  Oligosaccharide  Anticoagulant  Intrinsic Factor Xase  
Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycan 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 卷号: 112, 期号: 27, 页码: 8284-8289
作者:  Zhao, Longyan;  Wu, Mingyi;  Xiao, Chuang;  Yang, Lian;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Chen, Jun;  Chen, Jianchao;  Liu, Jikai;  Qin, Hongbo;  Zhao, Jinhua
浏览  |  Adobe PDF(1067Kb)  |  收藏  |  浏览/下载：322/44  |  提交时间：2015/12/17
Anticoagulant  Inhibitors  Oligosaccharides  Carbohydrates  Drug Discovery  
Structural Analysis and Anticoagulant Activities of the Novel Sulfated Fucan Possessing a Regular Well-Defined Repeating Unit from Sea Cucumber 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 4, 页码: 2063-2084
作者:  Wu, Mingyi;  Xu, Li;  Zhao, Longyan;  Xiao, Chuang;  Gao, Na;  Luo, Lan;  Yang, Lian;  Li, Zi;  Chen, Lingyun;  Zhao, Jinhua
浏览  |  Adobe PDF(2239Kb)  |  收藏  |  浏览/下载：299/56  |  提交时间：2015/06/29