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Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 10, 页码: 1619-1626
作者:  Xu, Hou-Chao;  Hu, Kun;  Shi, Xiao-Huo;  Tang, Jian-Wei;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(762Kb)  |  收藏  |  浏览/下载：203/48  |  提交时间：2019/07/29
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：320/72  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Schinortriterpenoids with Identical Configuration but Distinct ECD Spectra Generated by Nondegenerate Exciton Coupling 期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 6, 页码: 1500-1504
作者:  Shi, Yi-Ming;  Hu, Kun;  Pescitelli, Gennaro;  Liu, Miao;  Li, Xiao-Nian;  Du, Xue;  Xiao, Wei-Lie;  Sun, Han-Dong;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1601Kb)  |  收藏  |  浏览/下载：567/202  |  提交时间：2018/05/08
Polyketides from the endophytic fungus Phomopsis sp sh917 by using the one strain/many compounds strategy 期刊论文
TETRAHEDRON, 2017, 卷号: 73, 期号: 26, 页码: 3577-3584
作者:  Tang, Jian-Wei;  Wang, Wei-Guang;  Li, Ao;  Yan, Bing-Chao;  Chen, Rong;  Li, Xiao-Nian;  Du, Xue;  Sun, Han-Dong;  Pu, Jian-Xin
浏览  |  Adobe PDF(1225Kb)  |  收藏  |  浏览/下载：249/96  |  提交时间：2017/07/31
Endophytic Fungus  Phomopsis Sp.  Osmac Strategy  Polyketides  Antiangiogenic Activity  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
浏览  |  Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：483/230  |  提交时间：2017/02/28
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
浏览  |  Adobe PDF(13632Kb)  |  收藏  |  浏览/下载：328/36  |  提交时间：2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Natural products against hematological malignancies and identification of their targets 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 12, 页码: 1191-1201
作者:  Xu Ying;  Liu JinBao;  Wu YingLi;  Guo QingLong;  Sun HanDong;  Chen GuoQiang
Adobe PDF(756Kb)  |  收藏  |  浏览/下载：196/32  |  提交时间：2016/05/04
Natural Products  Adenanthin  Hematological Malignancies  Target Identification  
A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 10
作者:  Jiang,Shiyou;  Du,Jiacheng;  Kong,Qinghua;  Li,Chaocui;  Li,Yan;  Sun,Handong;  Pu,Jianxin;  Mao,Bingyu
浏览  |  Adobe PDF(7288Kb)  |  收藏  |  浏览/下载：223/61  |  提交时间：2016/01/19
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载：301/79  |  提交时间：2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Adenanthin targets proteins involved in the regulation of disulphide bonds 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2014, 卷号: 89, 期号: 2, 页码: 210-216
作者:  Muchowicz, Angelika;  Firczuk, Malgorzata;  Chlebowska, Justyna;  Nowis, Dominika;  Stachura, Joanna;  Barankiewicz, Joanna;  Trzeciecka, Anna;  Klossowski, Szymon;  Ostaszewski, Ryszard;  Zagozdzon, Radoslaw;  Pu, Jian-Xin;  Sun, Han-Dong;  Golab, Jakub
浏览  |  Adobe PDF(1121Kb)  |  收藏  |  浏览/下载：475/62  |  提交时间：2014/06/23
Adenanthin  Cancer  Peroxiredoxin  Protein Disulphide Isomerase  Thioredoxin