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Canthin-6-one ameliorates TNBS-induced colitis in rats by modulating inflammation and oxidative stress. An in vivo and in silico approach 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 186, 页码: 114490
作者:  Arunachalam,Karuppusamy;  Damazo,Amilcar Sabino;  Macho,Antonio;  Matchado,Monica Steffi;  Pavan,Eduarda;  Figueiredo,Fabiana de Freitas;  Oliveira,Darley Maria;  Duckworth,Carrie A.;  Thangaraj,Parimelazhagan;  Leonti,Marco;  de Oliveira Martins,Domingos Tabajara
收藏  |  浏览/下载:47/0  |  提交时间:2022/04/02
Canthin-6-one  Inflammatory bowel disease  TNBS  Cytokines  Colitis  BOWEL-DISEASE  PROINFLAMMATORY CYTOKINES  CLINICAL-ASPECTS  ACTIVITY SPECTRA  PATHOGENESIS  DOCKING  CELLS  ACCUMULATION  PREDICTION  MODEL  
Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift 期刊论文
PHYTOMEDICINE, 2021, 卷号: 91, 页码: 153707
作者:  Zhang,Xin-Tian;  Hu,Jing;  Su,Li-Hua;  Geng,Chang-An;  Chen,Ji-Jun
Adobe PDF(6313Kb)  |  收藏  |  浏览/下载:103/31  |  提交时间:2022/04/02
Artemisia atrovirens  Cervical cancer  ERK pathway  Cell metabolism  ALKALINE-PHOSPHATASE  SIGNALING PATHWAY  DIFFERENTIATION  APOPTOSIS  ERK  MECHANISMS  
Rubinoboletus ballouii polysaccharides exhibited immunostimulatory activities through toll-like receptor-4 via NF-kappa B pathway 期刊论文
PHYTOTHERAPY RESEARCH, 2021, 卷号: 35, 期号: 4, 页码: 2108-2118
作者:  Li,Long-Fei;  Yue,Grace G-L;  Chan,Ben C-L;  Zeng,Qiang;  Han,Quan-Bin;  Leung,Ping-Chung;  Fung,Kwok-Pui;  Liu,Ji-Kai;  Lau,Clara B-S
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immunostimulatory effects  immunosuppression  myelosuppression  polysaccharide  Rubinoboletus ballouii  toll‐  like receptor‐  4  GANODERMA-LUCIDUM  DENDRITIC CELLS  IN-VITRO  ANTITUMOR  MUSHROOMS  
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
作者:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
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Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
Biphenyl-type neolignans with NO inhibitory activity from the fruits of Magnolia tripetala 期刊论文
PHYTOCHEMISTRY LETTERS, 2021, 卷号: 44, 页码: 222-226
作者:  Nie,Wei;  Ding,Lin-Fen;  Lei,Tie;  Liu,Zhen-Xiang;  Li,Jin-Da;  Song,Liu-Dong;  Wu,Xing-De
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Magnolia tripetala  Biphenyl-type neolignan  NO inhibitory activity  Tripetalin A  STEM BARK  HONOKIOL DERIVATIVES  LIGNANS  LEAVES  SESQUITERPENOIDS  CONSTITUENTS  GROWTH  ALPHA  
Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway 期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
作者:  Yang,Hao-Jie;  Li,Ya-Nan;  Yan,Chen;  Yang,Jue;  Zeng,Yan-Rong;  Yi,Ping;  Li,Yan-Mei;  Hao,Xiao-Jiang;  Yuan,Chun-Mao
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Dysoxylum gotadhora  Rocaglaol derivatives  HCT116  Cytotoxic activity  MAPK pathway  FLAVAGLINES  
A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
作者:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
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enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects? 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Puno,Pema Tenzin;  Lau,Clara Bik-San
浏览  |  Adobe PDF(1847Kb)  |  收藏  |  浏览/下载:68/16  |  提交时间:2022/04/02
Breast cancer  Mast cell  Macrophage  Natural products  Herbs  Extracts  TUMOR-ASSOCIATED MACROPHAGES  NF-KAPPA-B  MEDIATED ALLERGIC REACTIONS  PRO-INFLAMMATORY CYTOKINES  ANTIINFLAMMATORY ACTIVITY  ATOPIC-DERMATITIS  UMBROSA ROOT  TNF-ALPHA  IN-VIVO  C-KIT