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Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N-9-Methyl Group in the Conformation and Bioactivity 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 12
作者:  Wang, Zhe;  Zhao, Si-Meng;  Zhao, Li-Mei;  Chen, Xiao-Qiang;  Zeng, Guang-Zhi;  Tan, Ning-Hua
浏览  |  Adobe PDF(805Kb)  |  收藏  |  浏览/下载：703/186  |  提交时间：2016/02/01
Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 8
作者:  Yang, Li-Ping;  Jiang, Fang-Jie;  Wu, Gui-Sheng;  Deng, Ke;  Wen, Meng;  Zhou, Xiaoju;  Hong, Xuechuan;  Zhu, Michael X.;  Luo, Huai-Rong
浏览  |  Adobe PDF(1207Kb)  |  收藏  |  浏览/下载：236/76  |  提交时间：2016/01/19
Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 5, 页码: e0127092
作者:  Liu, Yanchun;  Yang, Hui;  Chen, Tianxing;  Luo, Yongbin;  Xu, Zheyuan;  Li, Ying;  Yang, Jiahui;  Yang,JH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming,Yunnan,Peoples R China.;  yangjiahui@mail.kib.ac.cn
Adobe PDF(1997Kb)  |  收藏  |  浏览/下载：259/73  |  提交时间：2015/07/20
Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 7, 页码: e103760
作者:  Kong, Yanjie;  Chen, Jianchao;  Zhou, Zhongmei;  Xia, Houjun;  Qiu, Ming-Hua;  Chen, Ceshi;  Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming,Yunnan,Peoples R China.;  qiuminghua@mail.kib.ac.cn;  chenc@mail.kiz.ac.cn
Adobe PDF(3184Kb)  |  收藏  |  浏览/下载：204/39  |  提交时间：2014/11/25
Inhibitory-activity  Signaling Pathway  Carcinoma  Growth  Activation  
The Apoptotic Effect of D Rhamnose beta-Hederin, a Novel Oleanane-Type Triterpenoid Saponin on Breast Cancer Cells 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 3, 页码: e90848
作者:  Cheng, Lin;  Xia, Tian-Song;  Wang, Yi-Fen;  Zhou, Wenbin;  Liang, Xiu-Qing;  Xue, Jin-Qiu;  Shi, Liang;  Wang, Ying;  Ding, Qiang
Adobe PDF(4818Kb)  |  收藏  |  浏览/下载：303/79  |  提交时间：2014/05/16
Oxygen Species Generation  Bcl-2 Family Proteins  Platycodon-grandiflorum  Ginsenoside Rh2  Hepatoma-cells  Mapk Pathways  Anticancer  Activation  Induction  Death  
Shizukaol D Isolated from Chloranthus japonicas Inhibits AMPK-Dependent Lipid Content in Hepatic Cells by Inducing Mitochondrial Dysfunction 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e73527
作者:  Hu, Rongkuan;  Yan, Huan;  Hao, Xiaojiang;  Liu, Haiyang;  Wu, Jiarui
浏览  |  Adobe PDF(1041Kb)  |  收藏  |  浏览/下载：562/78  |  提交时间：2013/10/16
Activated Protein-kinase  Fatty-acid Oxidation  Respiratory Complex-i  Insulin-resistance  Malonyl-coa  Signaling Pathways  Glucose-uptake  L6 Myotubes  Hepg2 Cells  Metformin  
alpha-Mangostin Induces Apoptosis and Suppresses Differentiation of 3T3-L1 Cells via Inhibiting Fatty Acid Synthase 期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 3, 页码: e33376
作者:  Quan, Xiaofang;  Wang, Yi;  Ma, Xiaofeng;  Liang, Yan;  Tian, Weixi;  Ma, Qingyun;  Jiang, Hezhong;  Zhao, Youxing
Adobe PDF(767Kb)  |  收藏  |  浏览/下载：423/174  |  提交时间：2012/06/07
Aconitum Transsectum  Diterpenoid Alkaloids  Aconitramines d And e  Norditerpenoid Alkaloids  
Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma 期刊论文
PLOS ONE, 2011, 卷号: 6, 期号: 7, 页码: e21930
作者:  Liu, Ying;  Chen, Xiao-Qin;  Liang, Heng-Xing;  Zhang, Feng-Xiang;  Zhang, Bo;  Jin, Jie;  Chen, Yong-Long;  Cheng, Yong-Xian;  Zhou, Guang-Biao
Adobe PDF(877Kb)  |  收藏  |  浏览/下载：471/120  |  提交时间：2012/03/16
Nf-kappa-b  Cell-cycle Control  Overcomes Drug-resistance  Centipeda-minima  Antitumor-activity  Kinase-activity  Human Cancer  In-vitro  Activation  Expression  
Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer 期刊论文
PLOS ONE, 2011, 卷号: 6, 期号: 5, 页码: e20159
作者:  Ma, Liang;  Wen, Zhe-Sheng;  Liu, Zi;  Hu, Zheng;  Ma, Jun;  Chen, Xiao-Qin;  Liu, Yong-Qiang;  Pu, Jian-Xin;  Xiao, Wei-Lie;  Sun, Han-Dong;  Zhou, Guang-Biao
Adobe PDF(634Kb)  |  收藏  |  浏览/下载：347/104  |  提交时间：2012/03/16
Gastric-cancer  Breast-cancer  Phospho-akt  Smoking  Cells  Carcinoma  Survival  Leukemia  China