Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma | |
Liu, Ying1,2,3; Chen, Xiao-Qin4; Liang, Heng-Xing5; Zhang, Feng-Xiang1,2; Zhang, Bo1,2; Jin, Jie6; Chen, Yong-Long1,2; Cheng, Yong-Xian5; Zhou, Guang-Biao1,2 | |
通讯作者 | yxcheng@mail.kib.ac.cn ; gbzhou@ioz.ac.cn |
2011-07-06 | |
发表期刊 | PLOS ONE |
ISSN | 1932-6203 |
卷号 | 6期号:7页码:e21930 |
摘要 | Background: Multiple myeloma (MM) is a disease of cell cycle dysregulation while cell cycle modulation can be a target for MM therapy. In this study we investigated the effects and mechanisms of action of a sesquiterpene lactone 6-O-angeloylplenolin (6-OAP) on MM cells. |
关键词 | Nf-kappa-b Cell-cycle Control Overcomes Drug-resistance Centipeda-minima Antitumor-activity Kinase-activity Human Cancer In-vitro Activation Expression |
学科领域 | Biology |
DOI | 10.1371/journal.pone.0021930 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000292632000037 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/3966 |
专题 | 中国科学院东亚植物多样性与生物地理学重点实验室 |
作者单位 | 1.Chinese Acad Sci, Inst Zool, Guangzhou Inst Biomed & Hlth, Beijing, Peoples R China 2.Chinese Acad Sci, Inst Zool, State Key Lab Biomembrane & Membrane Biotechnol, Beijing, Peoples R China 3.Univ Sci & Technol China, Sch Life Sci, Hefei 230026, Peoples R China 4.Sun Yat Sen Univ, Canc Hosp, Dept Hematol, Guangzhou 510275, Guangdong, Peoples R China 5.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming, Peoples R China 6.Zhejiang Univ, Coll Med, Affiliated Hosp 1, Dept Hematol, Hangzhou 310003, Zhejiang, Peoples R China |
推荐引用方式 GB/T 7714 | Liu, Ying,Chen, Xiao-Qin,Liang, Heng-Xing,et al. Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma[J]. PLOS ONE,2011,6(7):e21930. |
APA | Liu, Ying.,Chen, Xiao-Qin.,Liang, Heng-Xing.,Zhang, Feng-Xiang.,Zhang, Bo.,...&Zhou, Guang-Biao.(2011).Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma.PLOS ONE,6(7),e21930. |
MLA | Liu, Ying,et al."Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma".PLOS ONE 6.7(2011):e21930. |
条目包含的文件 | 下载所有文件 | |||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
201203160043.pdf(877KB) | 开放获取 | -- | 浏览 下载 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论