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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载:193/0  |  提交时间:2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Rapid discovery and functional characterization of diterpene synthases from basidiomycete fungi by genome mining 期刊论文
FUNGAL GENETICS AND BIOLOGY, 2019, 卷号: 128, 页码: 36-42
作者:  Li, Xin-Lin;  Xu, Yu-Xing;  Li, Yuan;  Zhang, Rui;  Hu, Tian-Yuan;  Su, Ping;  Zhou, Man;  Tang, Ting;  Zeng, Ying;  Yang, Yan-Long;  Gao, Wei
浏览  |  Adobe PDF(1544Kb)  |  收藏  |  浏览/下载:257/44  |  提交时间:2019/07/29
Basidiomycete  Ditepene synthase  Genome mining  Cembrane diterpene  (-)-cyatha-3,12-diene  Ent-kauran-16 alpha-ol  
Characterization of a sesquiterpene cyclase from the glandular trichomes of Leucosceptrum canum for sole production of cedrol in Escherichia coli and Nicotiana benthamiana 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162, 页码: 121-128
作者:  Luo, Fei;  Ling, Yi;  Li, De-Sen;  Tang, Ting;  Liu, Yan-Chun;  Liu, Yan;  Li, Sheng-Hong
浏览  |  Adobe PDF(2851Kb)  |  收藏  |  浏览/下载:226/38  |  提交时间:2019/07/29
Leucosceptrum canum  Lamiaceae  Cedrol  Sesquiterpene cylase  Cedrol synthase  Heterologous production  Synthetic biology  
Niduterpenoids A and B: Two Sesterterpenoids with a Highly Congested Hexacyclic 5/5/5/5/3/5 Ring System from the Fungus Aspergillus nidulans 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 7, 页码: 2290-2293
作者:  Li, Qin;  Chen, Chunmei;  Wei, Mengsha;  Dai, Chong;  Cheng, Li;  Tao, Jiafeng;  Li, Xiao-Nian;  Wang, Jianping;  Sun, Weiguang;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1173Kb)  |  收藏  |  浏览/下载:189/13  |  提交时间:2019/05/24
Diterpene synthases facilitating production of the kaurane skeleton of eriocalyxin B in the medicinal plant Isodon eriocalyx 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 158, 页码: 96-102
作者:  Du, Gang;  Gong, Hai-Yan;  Feng, Ke-Na;  Chen, Qian-Qian;  Yang, Yan-Long;  Fu, Xiao-Li;  Lu, Shan;  Zeng, Ying
Adobe PDF(1880Kb)  |  收藏  |  浏览/下载:242/50  |  提交时间:2019/03/18
Isodon eriocalyx  Lamiaceae  Biosynthesis  Diterpenoids  Copalyl diphosphate synthase  Kaurene synthase  IeCPS3  IeKS1  
Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids 期刊论文
NATURE COMMUNICATIONS, 2016, 卷号: 7, 期号: 1, 页码: 1
作者:  Yan, Yijun;  Yang, Jing;  Yu, Zhiyin;  Yu, Mingming;  Ma, Ya-Tuan;  Wang, Li;  Su, Can;  Luo, Jianying;  Horsman, Geoffrey P.;  Huang, Sheng-Xiong
Adobe PDF(1066Kb)  |  收藏  |  浏览/下载:325/93  |  提交时间:2017/01/05
Peltate glandular trichomes of Colquhounia seguinii harbor new defensive clerodane diterpenoids 期刊论文
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2014, 卷号: 56, 期号: 9, 页码: 928-940
作者:  Li, Chun-Huan;  Liu, Yan;  Hua, Juan;  Luo, Shi-Hong;  Li, Sheng-Hong;  Li,SH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  shli@mail.kib.ac.cn
Adobe PDF(2576Kb)  |  收藏  |  浏览/下载:283/83  |  提交时间:2014/11/25
Colquhounia Seguinii Vaniot  Peltate Glandular Trichomes  Laser Microdissection  Clerodane Diterpenoids  Antifeedant And Antifungal Activities  
Inhibition of 11 beta-HSD1 by Tetracyclic Triterpenoids from Euphorbia kansui 期刊论文
MOLECULES, 2012, 卷号: 17, 期号: 10, 页码: 11826-11838
作者:  Guo, Jie;  Zhou, Li-Yan;  He, Hong-Ping;  Leng, Ying;  Yang, Zhen;  Hao, Xiao-Jiang
Adobe PDF(1631Kb)  |  收藏  |  浏览/下载:319/64  |  提交时间:2013/01/22
Tetracyclic Triterpenoids  Euphorbia Kansui  Inhibition Of 11 Beta-hsd1  Docking  
IeCPS2 is potentially involved in the biosynthesis pharmacologically active Isodon diterpenoids rather than gibberellin 期刊论文
PHYTOCHEMISTRY, 2012, 卷号: 76, 页码: 32-39
作者:  Li, Jun-Ling;  Chen, Qian-Qian;  Jin, Qiu-Ping;  Gao, Juan;  Zhao, Pei-Ji;  Lu, Shan;  Zeng, Ying
Adobe PDF(644Kb)  |  收藏  |  浏览/下载:417/147  |  提交时间:2012/06/07
Isodon Eriocalyx  Lamiaceae  Enzymology  Labdane-related Diterpenoid  Copalyl Diphosphate Synthase  Isodon Ent-kauranoid  Iecps2  Iecps1  
Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2011, 卷号: 43, 期号: 10, 页码: 757-762
作者:  Xu, Wenyan;  Li, Liling;  Du, Liangcheng;  Tan, Ninghua
Adobe PDF(163Kb)  |  收藏  |  浏览/下载:297/99  |  提交时间:2012/04/10
Ribosomal Peptide  Cyclopeptides  Non-ribosomal Peptide Synthetase  Cyclization Mechanism