Niduterpenoids A and B: Two Sesterterpenoids with a Highly Congested Hexacyclic 5/5/5/5/3/5 Ring System from the Fungus Aspergillus nidulans

doi:10.1021/acs.orglett.9b00581

	Niduterpenoids A and B: Two Sesterterpenoids with a Highly Congested Hexacyclic 5/5/5/5/3/5 Ring System from the Fungus Aspergillus nidulans
	Li, Qin 1; Chen, Chunmei 1; Wei, Mengsha 1; Dai, Chong 1; Cheng, Li 1,2; Tao, Jiafeng 1; Li, Xiao-Nian 3; Wang, Jianping 1; Sun, Weiguang 1; Zhu, Hucheng 1; Zhang, Yonghui 1
通讯作者	Sun, Weiguang(weiguang_s@hust.edu.cn) ; Zhu, Hucheng(zhuhucheng@hust.edu.cn) ; Zhang, Yonghui(zhangyh@mails.tjmu.edu.cn)
	2019-04-05
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	21 期号:7 页码:2290-2293
摘要	Niduterpenoids A (1) and B (2), two sesterterpenoids with a highly congested hexacyclic 5/5/5/5/3/5 carbon skeleton but no unsaturated functional group, were isolated from Aspergillus nidulans. Their structures were determined by a combination of spectroscopic data and single-crystal X-ray diffraction analyses. Compounds 1 and 2 present the first examples of sesterterpenoids with a hexacyclic carbon ring system. Compound 1 showed no cytotoxicity but abolished 17-estradiol-induced cell proliferation (IC50 = 11.42 +/- 0.85 mu M).
DOI	10.1021/acs.orglett.9b00581
收录类别	SCI
语种	英语
WOS记录号	WOS:000464247500076
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/66342
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Sun, Weiguang; Zhu, Hucheng; Zhang, Yonghui
作者单位	1.Huazhong Univ Sci & Technol, Hubei Key Lab Nat Med Chem & Resource Evaluat, Sch Pharm, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China 2.Hubei Univ Med, Coll Pharm, Shiyan 442000, Peoples R China 3.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Li, Qin,Chen, Chunmei,Wei, Mengsha,et al. Niduterpenoids A and B: Two Sesterterpenoids with a Highly Congested Hexacyclic 5/5/5/5/3/5 Ring System from the Fungus Aspergillus nidulans[J]. ORGANIC LETTERS,2019,21(7):2290-2293.
APA	Li, Qin.,Chen, Chunmei.,Wei, Mengsha.,Dai, Chong.,Cheng, Li.,...&Zhang, Yonghui.(2019).Niduterpenoids A and B: Two Sesterterpenoids with a Highly Congested Hexacyclic 5/5/5/5/3/5 Ring System from the Fungus Aspergillus nidulans.ORGANIC LETTERS,21(7),2290-2293.
MLA	Li, Qin,et al."Niduterpenoids A and B: Two Sesterterpenoids with a Highly Congested Hexacyclic 5/5/5/5/3/5 Ring System from the Fungus Aspergillus nidulans".ORGANIC LETTERS 21.7(2019):2290-2293.

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