| Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases | |
| Xu, Wenyan1,2,3; Li, Liling2; Du, Liangcheng1; Tan, Ninghua2 | |
| 通讯作者 | Du, LC (reprint author), Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA |
| 2011-10-01 | |
| 发表期刊 | ACTA BIOCHIMICA ET BIOPHYSICA SINICA
 |
| ISSN | 1672-9145 |
| 卷号 | 43期号:10页码:757-762 |
| 摘要 | An increasing number of cyclopeptides have been discovered as products of ribosomal synthetic pathway. The biosynthetic study of these cyclopeptides has revealed interesting new mechanisms for cyclization. This review highlighted the recent discoveries in cyclization mechanisms for cyclopeptides synthesized independently of non-ribosomal peptide synthetases, including endopeptidase-catalyzed cyclization, intein-mediated cyclization, and peptide synthetase-catalyzed cyclization. This information may help to design hybrid ribosomal and non-ribosomal biosynthetic systems to produce novel cyclopeptides with various bioactivities. |
| 关键词 | Ribosomal Peptide Cyclopeptides Non-ribosomal Peptide Synthetase Cyclization Mechanism |
| 学科领域 | Biochemistry & Molecular Biology ; Biophysics |
| DOI | 10.1093/abbs/gmr062 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000295411300002 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/5373 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Wenyan,Li, Liling,Du, Liangcheng,et al. Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2011,43(10):757-762. |
| APA | Xu, Wenyan,Li, Liling,Du, Liangcheng,&Tan, Ninghua.(2011).Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,43(10),757-762. |
| MLA | Xu, Wenyan,et al."Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 43.10(2011):757-762. |
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