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Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway 期刊论文
MOLECULAR METABOLISM, 2020
作者:  Liu, Siwen;  Huang, Suling;  Wu, Xingde;  Feng, Ying;  Shen, Yu;  Zhao, Qin-shi;  Leng, Ying
浏览  |  Adobe PDF(3899Kb)  |  收藏  |  浏览/下载：112/32  |  提交时间：2021/01/05
Vibsanin A sensitizes human acute myeloid leukemia cells to tyrosine kinase inhibitor-induced myeloid differentiation via activation of PKC and upregulation of Lyn 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 502, 期号: 1, 页码: 110-115
作者:  Shen, Xing;  Xing, Shuang;  Zhang, Lu;  Wang, Fangmin;  Ou, Hongling;  Shan, Yajun;  Xiao, He;  Xiang, Guolin;  Wang, Xinru;  Zhao, Qinshi;  Cong, Yuwen;  Yu, Zuyin
收藏  |  浏览/下载：86/0  |  提交时间：2019/03/29
Sauruchinenols A and B, unprecedented monocyclic diterpenes with new carbon skeleton from the aerial parts of Saururus chinensis 期刊论文
FITOTERAPIA, 2017, 卷号: 116, 页码: 116-120
作者:  Gao, Xiu;  He, Juan;  Wu, Xing-De;  Peng, Li-Yan;  Shao, Li-Dong;  Li, Yan;  Cheng, Xiao;  Zhao, Qin-Shi
浏览  |  Adobe PDF(503Kb)  |  收藏  |  浏览/下载：310/39  |  提交时间：2017/04/18
Saururus Chinensis  Saururaceae  Sauruchinenols A-d  Anti-no Production  
Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 66689-66699
作者:  Zhang, Ruowen;  Che, Xun;  Zhang, Jingjie;  Li, Yang;  Li, Jingxia;  Deng, Xu;  Zhu, Junlan;  Jin, Honglei;  Zhao, Qinshi;  Huang, Chuanshu
浏览  |  Adobe PDF(9106Kb)  |  收藏  |  浏览/下载：199/45  |  提交时间：2017/01/05
Chel a  Human Bladder Cancer  Apoptosis  Phlpp2  C-jun  
neo-Clerodanes from the aerial parts of Salvia leucantha 期刊论文
TETRAHEDRON, 2016, 卷号: 72, 期号: 35, 页码: 5507-5514
作者:  Jiang, Yong-Jun;  Su, Jia;  Shi, Xin;  Wu, Xing-De;  Chen, Xuan-Qin;  He, Juan;  Shao, Li-Dong;  Li, Xiao-Nian;  Peng, Li-Yan;  Li, Rong-Tao;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1147Kb)  |  收藏  |  浏览/下载：237/49  |  提交时间：2016/11/04
Neo-clerodanes  Salvia Leucantha  Cytotoxicity  Heat Shock Protein 90 Inhibitor  Acetyl Cholinesterase Inhibitory Activity  
Bioactive sesquiterpenoids from the flowers of Inula japonica 期刊论文
PHYTOCHEMISTRY, 2016, 卷号: 129, 页码: 68-76
作者:  Wu, Xing-De;  Ding, Lin-Fen;  Tu, Wen-Chao;  Yang, Hui;  Su, Jia;  Peng, Li-Yan;  Li, Yan;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1070Kb)  |  收藏  |  浏览/下载：259/62  |  提交时间：2016/11/04
Inula Japonica  Asteraceae  Sesquiterpenoids  Inujaponins A-i  Cytotoxicity  Nitric Oxide (No)  
Natural Product Vibsanin A Induces Differentiation of Myeloid Leukemia Cells through PKC Activation 期刊论文
CANCER RESEARCH, 2016, 卷号: 76, 期号: 9, 页码: 2698-2709
作者:  Yu, Zu-Yin;  Xiao, He;  Wang, Li-Mei;  Shen, Xing;  Jing, Yu;  Wang, Lin;  Sun, Wen-Feng;  Zhang, Yan-Feng;  Cui, Yu;  Shan, Ya-Jun;  Zhou, Wen-Bing;  Xing, Shuang;  Xiong, Guo-Lin;  Liu, Xiao-Lan;  Dong, Bo;  Feng, Jian-Nan;  Wang, Li-Sheng;  Luo, Qing-Liang;  Zhao, Qin-Shi;  Cong, Yu-Wen
浏览  |  Adobe PDF(1368Kb)  |  收藏  |  浏览/下载：284/95  |  提交时间：2016/08/22
Vibsanin B Preferentially Targets HSP90b, Inhibits Interstitial Leukocyte Migration, and Ameliorates Experimental Autoimmune Encephalomyelitis 期刊论文
JOURNAL OF IMMUNOLOGY, 2015, 卷号: 194, 期号: 9, 页码: 4489-4497
作者:  Ye, Bai-Xin;  Deng, Xu;  Shao, Li-Dong;  Lu, Ying;  Xiao, Run;  Liu, Yi-Jie;  Jin, Yi;  Xie, Yin-Yin;  Zhao, Yan;  Luo, Liu-Fei;  Ma, Shun;  Gao, Ming;  Zhang, Lian-Ru;  He, Juan;  Zhang, Wei-Na;  Chen, Yi;  Xia, Cheng-Feng;  Deng, Min;  Liu, Ting-Xi;  Zhao, Qin-Shi;  Chen, Sai-Juan;  Chen, Zhu;  Chen,Z (reprint author),Shanghai Jiao Tong Univ,RuiJin Hosp,Sch Med,197 Rui Jin Rd 2,Shanghai 200025,Peoples R China.;  qinshizhao@mail.kib.ac.cn;  sjchen@stn.sh.cn;  zchen@stn.sh.cn
浏览  |  Adobe PDF(1516Kb)  |  收藏  |  浏览/下载：273/43  |  提交时间：2015/07/20
Hupehenols A-E, Selective 11 beta-Hydroxysteroid Dehydrogenase Type 1 (11 beta-HSD1) Inhibitors from Viburnum hupehense 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2015, 卷号: 78, 期号: 2, 页码: 330-334
作者:  Chen, Xuan-Qin;  Shao, Li-Dong;  Pal, Mahesh;  Shen, Yu;  Cheng, Xiao;  Xu, Gang;  Peng, Li-Yan;  Wang, Kou;  Pan, Zheng-Hong;  Li, Ming-Ming;  Leng, Ying;  He, Juan;  Zhao, Qin-Shi;  He,J (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Yunnan,Peoples R China.;  hejuan@mail.kib.ac.cn;  qinshizhao@mail.kib.ac.cn
浏览  |  Adobe PDF(811Kb)  |  收藏  |  浏览/下载：304/88  |  提交时间：2015/06/29
Crucial Role of c-Jun Phosphorylation at Ser63/73 Mediated by PHLPP Protein Degradation in the Cheliensisin A Inhibition of Cell Transformation 期刊论文
CANCER PREVENTION RESEARCH, 2014, 卷号: 7, 期号: 12, 页码: 1270-1281
作者:  Zhu, Junlan;  Zhang, Jingjie;  Huang, Haishan;  Li, Jingxia;  Yu, Yonghui;  Jin, Honglei;  Li, Yang;  Deng, Xu;  Gao, Jimin;  Zhao, Qinshi;  Huang, Chuanshu;  Huang,CS (reprint author),NYU,Sch Med,Nelson Inst Environm Med,57 Old Forge Rd,Tuxedo Pk,NY 10987 USA.
浏览  |  Adobe PDF(3644Kb)  |  收藏  |  浏览/下载：200/38  |  提交时间：2015/01/20
Naturally Occurring Substances  Magnetic-resonance Spectroscopy  Stem-bark  Melodinus-henryi  Conformational-analysis  (+)-scholarisine  Mechanism  Leaves  Seeds  Camptothecin  Indole Alkaloids  Cytotoxicity  Absolute Configuration  Vinca Major