neo-Clerodanes from the aerial parts of Salvia leucantha

doi:10.1016/j.tet.2016.07.037

	neo-Clerodanes from the aerial parts of Salvia leucantha
	Jiang, Yong-Jun; Su, Jia; Shi, Xin; Wu, Xing-De; Chen, Xuan-Qin; He, Juan; Shao, Li-Dong; Li, Xiao-Nian; Peng, Li-Yan; Li, Rong-Tao; Zhao, Qin-Shi
	2016-09-01
发表期刊	TETRAHEDRON
卷号	72 期号:35 页码:5507-5514
摘要	Ten new neo-clerodane derivatives (1-10) and 10 known diterpenoids were identified from the aerial parts of Salvia leucantha. The structures of 1-10 were established by 1D and 2D NMR spectroscopic data analysis. The absolute configurations of 1, 3, 6, and 7 were determined by X-ray diffraction data. Compound 16 exhibited cytotoxicity against HCT116, BT474, and HepG2 cancer cell lines and was identified as a heat shock protein 90 inhibitor. Compounds 8, 15, and 16 exhibited moderate acetyl cholinesterase inhibitory activity.(C) 2016 Elsevier Ltd. All rights reserved.
关键词	Neo-clerodanes Salvia Leucantha Cytotoxicity Heat Shock Protein 90 Inhibitor Acetyl Cholinesterase Inhibitory Activity
DOI	10.1016/j.tet.2016.07.037
收录类别	SCI
语种	英语
WOS记录号	WOS:000381530900031
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/28583
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Jiang, Yong-Jun,Su, Jia,Shi, Xin,et al. neo-Clerodanes from the aerial parts of Salvia leucantha[J]. TETRAHEDRON,2016,72(35):5507-5514.
APA	Jiang, Yong-Jun.,Su, Jia.,Shi, Xin.,Wu, Xing-De.,Chen, Xuan-Qin.,...&Zhao, Qin-Shi.(2016).neo-Clerodanes from the aerial parts of Salvia leucantha.TETRAHEDRON,72(35),5507-5514.
MLA	Jiang, Yong-Jun,et al."neo-Clerodanes from the aerial parts of Salvia leucantha".TETRAHEDRON 72.35(2016):5507-5514.

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