neo-Clerodanes from the aerial parts of Salvia leucantha | |
Jiang, Yong-Jun; Su, Jia; Shi, Xin; Wu, Xing-De; Chen, Xuan-Qin; He, Juan; Shao, Li-Dong; Li, Xiao-Nian; Peng, Li-Yan; Li, Rong-Tao; Zhao, Qin-Shi | |
2016-09-01 | |
发表期刊 | TETRAHEDRON |
卷号 | 72期号:35页码:5507-5514 |
摘要 | Ten new neo-clerodane derivatives (1-10) and 10 known diterpenoids were identified from the aerial parts of Salvia leucantha. The structures of 1-10 were established by 1D and 2D NMR spectroscopic data analysis. The absolute configurations of 1, 3, 6, and 7 were determined by X-ray diffraction data. Compound 16 exhibited cytotoxicity against HCT116, BT474, and HepG2 cancer cell lines and was identified as a heat shock protein 90 inhibitor. Compounds 8, 15, and 16 exhibited moderate acetyl cholinesterase inhibitory activity.(C) 2016 Elsevier Ltd. All rights reserved. |
关键词 | Neo-clerodanes Salvia Leucantha Cytotoxicity Heat Shock Protein 90 Inhibitor Acetyl Cholinesterase Inhibitory Activity |
DOI | 10.1016/j.tet.2016.07.037 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000381530900031 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/28583 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
推荐引用方式 GB/T 7714 | Jiang, Yong-Jun,Su, Jia,Shi, Xin,et al. neo-Clerodanes from the aerial parts of Salvia leucantha[J]. TETRAHEDRON,2016,72(35):5507-5514. |
APA | Jiang, Yong-Jun.,Su, Jia.,Shi, Xin.,Wu, Xing-De.,Chen, Xuan-Qin.,...&Zhao, Qin-Shi.(2016).neo-Clerodanes from the aerial parts of Salvia leucantha.TETRAHEDRON,72(35),5507-5514. |
MLA | Jiang, Yong-Jun,et al."neo-Clerodanes from the aerial parts of Salvia leucantha".TETRAHEDRON 72.35(2016):5507-5514. |
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