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Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 卷号: 21, 期号: 10, 页码: 977-984
作者:  Li, Xing-Ren;  Fu, Qiang;  Zhou, Min;  Hu, Kun;  Du, Xue;  Li, Xiao-Nian;  Sun, Han-Dong;  Yue, Jian-Bo;  Zhang, Hong-Bin;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1263Kb)  |  收藏  |  浏览/下载：243/49  |  提交时间：2019/10/28
Lamiaceae  ent-clerodane diterpenoids  Isodon scoparius  X-ray diffraction  autophagic activity  
Blocking ROR1 enhances the roles of erlotinib in lung adenocarcinoma cell lines 期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 3, 页码: 2977-2984
作者:  Wang, Hui-Li;  Liu, Yan-Chun;  Long, Ming-Peng;  Zheng, Chuan;  Yang, Jia-Hui
浏览  |  Adobe PDF(667Kb)  |  收藏  |  浏览/下载：163/45  |  提交时间：2019/11/07
receptor tyrosine kinase-like orphan receptor 1  lung adenocarcinoma  erlotinib resistance  AKT  mammalian target of rapamycin  small interfering RNA  
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：247/70  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Aqueous extract of clove inhibits tumor growth by inducing autophagy through AMPK/ULK pathway 期刊论文
PHYTOTHERAPY RESEARCH, 2019, 卷号: 33, 期号: 7, 页码: 1794-1804
作者:  Li, Cong;  Xu, Huanli;  Chen, Xiaoliang;  Chen, Jijun;  Li, Xiao;  Qiao, Gan;  Tian, Ye;  Yuan, Ru;  Su, Shuonan;  Liu, Xiaohui;  Lin, Xiukun
浏览  |  Adobe PDF(1218Kb)  |  收藏  |  浏览/下载：186/49  |  提交时间：2019/09/10
AMPK  anticancer  aqueous extract of clove  autophagy  traditional Chinese medicine  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(3915Kb)  |  收藏  |  浏览/下载：244/41  |  提交时间：2019/07/29
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：274/63  |  提交时间：2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Sense Ginsenosides From Ginsengs: Structure-Activity Relationship in Autophagy 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2019, 卷号: 14, 期号: 6, 页码: 10
作者:  Wu, Tao;  Kwaku, Osafo Raymond;  Li, Hai-Zhou;  Yang, Chong-Ren;  Ge, Long-Jiao;  Xu, Min
Adobe PDF(1069Kb)  |  收藏  |  浏览/下载：188/42  |  提交时间：2019/09/10
ginsengs  ginsenosides  structure-activity relationship  autophagy  
A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 页码: 9
作者:  Adelakun, Tiwalade A.;  Ding, Xiao;  Ombati, Rose M.;  Zhao, Ning-Dong;  Obodozie-Ofoegbu, Obiageri;  Di, Ying-Tong;  Zhang, Yu;  Hao, Xiao-Jiang
Adobe PDF(1037Kb)  |  收藏  |  浏览/下载：325/160  |  提交时间：2019/07/29
Euphorbia fischeriana Steud  highly oxygenated abietanes  phorbol esters  lysosomal biogenesis  
B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells 期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 18, 页码: 3371-3386
作者:  Zhou, Hongyu;  Yu, Chunlei;  Kong, Lingmei;  Xu, Xiaoliang;  Yan, Juming;  Li, Yingchao;  An, Tao;  Gong, Liang;  Gong, Yaxiao;  Zhu, Huifang;  Zhang, Hongbin;  Yang, Xiaodong;  Li, Yan
Adobe PDF(5225Kb)  |  收藏  |  浏览/下载：257/32  |  提交时间：2019/06/24
RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 9, 页码: 14
作者:  Guo, Di;  Wang, Yurong;  Wang, Jing;  Song, Lihua;  Wang, Zhe;  Mao, Bingyu;  Tan, Ninghua
Adobe PDF(9639Kb)  |  收藏  |  浏览/下载：161/30  |  提交时间：2019/07/29
RA-XII  lipogenesis  SCAP  SREBP  liver cancer