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Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models 期刊论文
CELL RESEARCH, 2021, 卷号: 31, 期号: 1, 页码: 17-24
Authors:  Wang,Gan;  Yang,Meng-Li;  Duan,Zi-Lei;  Liu,Feng-Liang;  Jin,Lin;  Long,Cheng-Bo;  Zhang,Min;  Tang,Xiao-Peng;  Xu,Ling;  Li,Ying-Chang;  Kamau,Peter Muiruri;  Yang,Lian;  Liu,Hong-Qi;  Xu,Jing-Wen;  Chen,Jie-Kai;  Zheng,Yong-Tang;  Peng,Xiao-Zhong;  Lai,Ren
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SARS  ENTRY  MERS  
Multiple in vitro biological effects of phenolic compounds from Terminalia chebula var. tomentella 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 275, 页码: 114135
Authors:  Zhang,Xiao-Rui;  Qiao,Yi-Jun;  Zhu,Hong-Tao;  Kong,Qing-Hua;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
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Terminalia chebula var  tomentella  Combretaceae  Fructus Chebulae  Hydrolyzed tannins  Simple phenolic compounds  Anti-inflammation  Anti-diabetes  NITRIC-OXIDE  ANTIOXIDANT  TANNINS  CONSTITUENTS  VALIDATION  ALGORITHM  ESTERS  FRUITS  
Phyllanthacidoid U: a new N-glycosyl norbisabolane sesquiterpene from Phyllanthus acidus (L.) skeels 期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 21, 页码: 3540-3547
Authors:  Xin,Ying;  Xu,Min;  Wang,Ya-Feng;  Zheng,Xiao-Hong;  Zhu,Hong-Tao;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
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Phyllanthus acidus  phyllanthacidoid U  norbisabolane sesquiterpenoid  amide  TUSSILAGO-FARFARA  FLOWER BUDS  EXTRACTS  PLANTS  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
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Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Yunnan-Guizhou Plateau: a mycological hotspot 期刊论文
PHYTOTAXA, 2021, 卷号: 523, 期号: 1, 页码: 1-31
Authors:  Wijayawardene,Nalin N.;  Dissanayake,Lakmali S.;  Dai,Dong-Qi;  Li,Qi-Rui;  Xiao,Yuanpin;  Wen,Ting-Chi;  Karunarathna,Samantha C.;  Wu,Hai-Xia;  Zhang,Huang;  Tibpromma,Saowaluck;  Kang,Ji-Chuan;  Wang,Yong;  Shen,Xiang-Chun;  Tang,Li-Zhou;  Deng,Chun-Ying;  Liu,Yanxia;  Kang,Yingqian
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2 new species  polyphasic approach  six new records  species diversity  taxonomy  MULTIPLE SEQUENCE ALIGNMENT  SP-NOV  PHYLOGENETIC CLASSIFICATION  ENTOMOPATHOGENIC GENUS  MULTIGENE PHYLOGENY  FUNGI  CORDYCEPS  GENERA  DIVERSITY  LINEAGES  
Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 11, 页码: 4158-4162
Authors:  Hu,Bin-Yuan;  Zhao,Yun-Li;  Xiong,Deng-Sen;  He,Ying-Jie;  Zhou,Zhong-Shun;  Zhu,Pei-Feng;  Wang,Zhao-Jie;  Wang,Yong-Liang;  Zhao,Li-Xing;  Luo,Xiao-Dong
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SKELETONS  
Structural characterization of oligosaccharides from free radical depolymerized fucosylated glycosaminoglycan and suggested mechanism of depolymerization 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 270, 页码: 118368
Authors:  Chen,Ru;  Yin,Ronghua;  Li,Shanni;  Pan,Ying;  Mao,Hui;  Cai,Ying;  Lin,Lisha;  Wang,Weili;  Zhang,Taocui;  Zhou,Lutan;  Gao,Na;  Luo,Xiaodong;  Zhao,Jinhua
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Fucosylated glycosaminoglycan  Free radical depolymerization  Chemical structure  Oligosaccharide  NMR  INTRINSIC TENASE COMPLEX  ANTICOAGULANT ACTIVITIES  SEA-CUCUMBER  CHONDROITIN SULFATE  PHYSICOCHEMICAL CHARACTERISTICS  FACTOR XASE  POLYSACCHARIDES  DERIVATIVES  HEPARIN  
Comparison of chemical constituents in diverse zanthoxylum herbs, and evaluation of their relative antibacterial and nematicidal activity 期刊论文
FOOD BIOSCIENCE, 2021, 卷号: 42, 页码: 101206
Authors:  Wang,Zhao-Jie;  Zhou,Ying;  Shi,Xiao-Long;  Xia,Xiao;  He,Ying-Jie;  Zhu,Yan-Yan;  Xie,Tian-Zhen;  Liu,Tie;  Xu,Xiang-Juan;  Luo,Xiao-Dong
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Zanthoxylum herbs  Antibacterial  Nematicidal  Mass spectrometry  BUNGEANUM MAXIM.  LIGNANS  IDENTIFICATION  ARMATUM  LEAVES  AMIDES  ROOTS  OILS  
The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
Authors:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
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Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
Bioactivity Ingredients of Chaenomeles speciosa against Microbes: Characterization by LC-MS and Activity Evaluation 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 16, 页码: 4686-4696
Authors:  Wang,Zhao-Jie;  Jin,Dan-Ni;  Zhou,Ying;  Sang,Xu-Yan;  Zhu,Yan-Yan;  He,Ying-Jie;  Xie,Tian-Zhen;  Dai,Zhi;  Zhao,Yun-Li;  Luo,Xiao-Dong
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antimicrobial  Chaenomeles speciosa  LC-MS  metabolomics  LUNG INFLAMMATION  ANTIOXIDANT  FRUITS  POLYSACCHARIDE