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A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
Favorite  |  View/Download:19/0  |  Submit date:2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 10, 页码: 1619-1626
Authors:  Xu, Hou-Chao;  Hu, Kun;  Shi, Xiao-Huo;  Tang, Jian-Wei;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
Favorite  |  View/Download:7/0  |  Submit date:2019/07/29
Structurally diverse diterpenoids from Isodon ternifolius collected from three regions 期刊论文
TETRAHEDRON, 2019, 卷号: 75, 期号: 19, 页码: 2797-2806
Authors:  Gou, Lei-Lei;  Hu, Kun;  Yang, Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Xiang, Chun-Lei;  Puno, Pema-Tenzin
Favorite  |  View/Download:22/0  |  Submit date:2019/06/24
Isodon ternifolius  Diterpenoids  Cytotoxic activity  NMR computation  ECD calculation  
Metabolic Activation of Myristicin and Its Role in Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 15, 页码: 4328-4336
Authors:  Zhu, Xu;  Wang, Yi-Kun;  Yang, Xiao-Nan;  Xiao, Xue-Rong;  Zhang, Ting;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Li, Fei
Favorite  |  View/Download:37/0  |  Submit date:2019/05/24
myristicin  1 '-hydroxymyristicin  metabolic activation  metabolomics  
(+)- and (-)-Alternarilactone A: Enantiomers with a Diepoxy-Cage-like Scaffold from an Endophytic Alternaria sp. 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 4, 页码: 735-740
Authors:  Tang, Jian-Wei;  Xu, Hou-Chao;  Wang, Wei-Guang;  Hu, Kun;  Zhou, Yuan-Fei;  Chen, Rong;  Li, Xiao-Nian;  Du, Xue;  Sun, Han-Dong;  Puno, Pema-Tenzin
Favorite  |  View/Download:89/0  |  Submit date:2019/06/24
Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 3, 页码: 771-775
Authors:  Tang, Jian-Wei;  Kong, Ling-Mei;  Zu, Wen-Yu;  Hu, Kun;  Li, Xiao-Nian;  Yan, Bing-Chao;  Wang, Wei-Guang;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
Favorite  |  View/Download:103/0  |  Submit date:2019/03/18
Maoeriocalysins A-D, four novel ent-kaurane diterpenoids from Isodon eriocalyx and their structure determination utilizing quantum chemical calculation in conjunction with quantitative interproton distance analysis 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 1, 页码: 45-53
Authors:  Yang, Qian;  Hu, Kun;  Yan, Bing-Chao;  Liu, Miao;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
Favorite  |  View/Download:82/0  |  Submit date:2019/03/18
Identifying long-term stable refugia for relict plant species in East Asia (vol 9, 4488, 2018) 期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9, 页码: 2
Authors:  Tang, Cindy Q.;  Matsui, Tetsuya;  Ohashi, Haruka;  Dong, Yi-Fei;  Momohara, Arata;  Herrando-Moraira, Sonia;  Qian, Shenhua;  Yang, Yongchuan;  Ohsawa, Masahiko;  Hong Truong Luu;  Grote, Paul J.;  Krestov, Pavel V.;  LePage, Ben;  Werger, Marinus;  Robertson, Kevin;  Hobohm, Carsten;  Wang, Chong-Yun;  Peng, Ming-Chun;  Chen, Xi;  Wang, Huan-Chong;  Su, Wen-Hua;  Zhou, Rui;  Li, Shuaifeng;  He, Long-Yuan;  Yan, Kai;  Zhu, Ming-Yuan;  Hu, Jun;  Yang, Ruo-Han;  Li, Wang-Jun;  Tomita, Mizuki;  Wu, Zhao-Lu;  Yan, Hai-Zhong;  Zhang, Guang-Fei;  He, Hai;  Yi, Si-Rong;  Gong, Hede;  Song, Kun;  Song, Ding;  Li, Xiao-Shuang;  Zhang, Zhi-Ying;  Han, Peng-Bin;  Shen, Li-Qin;  Huang, Diao-Shun;  Luo, Kang;  Lopez-Pujol, Jordi
Favorite  |  View/Download:108/0  |  Submit date:2018/12/27
Premnafulvol A: A Diterpenoid with a 6/5/7/3-Fused Tetracyclic Core and Its Biosynthetically Related Analogues from Premna fulva 期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 19, 页码: 6314-6317
Authors:  Pu, De-Bing;  Du, Bao-Wen;  Chen, Wen;  Gao, Jun-Bo;  Hu, Kun;  Shi, Nan;  Li, Yi-Ming;  Zhang, Xing-Jie;  Zhang, Rui-Han;  Li, Xiao-Nian;  Zhang, Hong-Bin;  Wang, Fei;  Xiao, Wei-Lie
Favorite  |  View/Download:82/0  |  Submit date:2018/11/12
Metabolic profiling of the anti-tumor drug regorafenib in mice 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 卷号: 159, 页码: 524-535
Authors:  Wang, Yi-Kun;  Xiao, Xue-Rong;  Xu, Kang-Ping;  Li, Fei
Favorite  |  View/Download:11/0  |  Submit date:2018/10/04
Regorafenib  Metabolomics  Multiple mass defect filters  Molecular docking