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Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
Authors:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
View  |  Adobe PDF(7289Kb)  |  Favorite  |  View/Download：149/27  |  Submit date：2024/07/10
Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Cytotoxic C-20 non-oxygenated ent-kaurane diterpenoids from Isodon wardii 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106512
Authors:  Tan,Qian;  Hu,Kun;  Li,Xiao-Nian;  Yang,Xing-Zhi;  Sun,Han-Dong;  Puno,Pema-Tenzin
View  |  Adobe PDF(3171Kb)  |  Favorite  |  View/Download：146/15  |  Submit date：2024/07/22
Isodon wardii  ent-Kauranoids  Cytotoxicity  Apoptosis  Cell cycle  
Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 11, 期号: 1, 页码: 37-46
Authors:  Dai,Jia-Meng;  Yan,Bing-Chao;  Kong,Ling-Mei;  Hu,Kun;  Li,Xing-Ren;  Li,Xiao-Nian;  Sun,Han-Dong;  Li,Yan;  Puno,Pema-Tenzin
View  |  Adobe PDF(1181Kb)  |  Favorite  |  View/Download：156/14  |  Submit date：2024/05/09
ENT-KAURANE DITERPENOIDS  ABIETANE DITERPENOIDS  A-D  DIMERS  OXIDATION  CYCLOADDUCTS  ACTIVATION  LIGANDS  IBX  
A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids 期刊论文
PLANT PHYSIOLOGY, 2022, 卷号: 188, 期号: 3, 页码: 1496-1506
Authors:  Song,Jiao-Jiao;  Fang,Xin;  Li,Chen-Yi;  Jiang,Yan;  Li,Jian-Xu;  Wu,Sheng;  Guo,Juan;  Liu,Yan;  Fan,Hang;  Huang,Yan-Bo;  Wei,Yu-Kun;  Kong,Yu;  Zhao,Qing;  Xu,Jing-Jing;  Hu,Yong-Hong;  Chen,Xiao-Ya;  Yang,Lei
Favorite  |  View/Download：170/0  |  Submit date：2022/04/02
MOLECULAR-CLONING  BIOSYNTHESIS  TANSHINONES  EVOLUTION  CYTOTOXICITY  SUPERFAMILY  OXYGENASES  APOPTOSIS  SYNTHASE  
Elevational patterns of functional diversity and trait of Delphinium (Ranunculaceae) in Hengduan Mountains, China 期刊论文
PLANT DIVERSITY, 2022, 卷号: 44, 期号: 1, 页码: 20-29
Authors:  Qian, Li-Shen;  Shi, Hong-Hua;  Ou, Xiao-Kun;  Sun, Hang
View  |  Adobe PDF(3002Kb)  |  Favorite  |  View/Download：156/24  |  Submit date：2024/03/11
Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 卷号: 44, 期号: 11, 页码: 2189-2205
Authors:  Wang,Yi-Kun;  Zhou,Zi-Meng;  Dai,Man-Yun;  Ma,Xiao-Fang;  Xiao,Xue-Rong;  Zhang,Shou-Wen;  Liu,Hong-Ning;  Li,Fei
View  |  Adobe PDF(2083Kb)  |  Favorite  |  View/Download：201/54  |  Submit date：2022/04/02
Fructus Aurantii  quality markers  metabolomics  serum pharmacochemistry  ultra high performance liquid chromatography  SERUM PHARMACOCHEMISTRY  RAT PLASMA  IDENTIFICATION  METABOLITES  IMMATURUS  COMPONENTS  EXTRACT  NEOHESPERIDIN  FINGERPRINT  NARINGIN  
A strategy combining solid-phase extraction, multiple mass defect filtering and molecular networking for rapid structural classification and annotation of natural products: characterization of chemical diversity in Citrus aurantium as a case study 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 卷号: 413, 期号: 11, 页码: 2879-2891
Authors:  Wang,Yi-Kun;  Xiao,Xue-Rong;  Zhou,Zi-Meng;  Xiao,Yao;  Zhu,Wei-Feng;  Liu,Hong-Ning;  Li,Fei
View  |  Adobe PDF(2565Kb)  |  Favorite  |  View/Download：172/18  |  Submit date：2022/04/02
Solid-phase extraction  Multiple mass defect filtering  Molecular networking  Natural products annotation  Structure and substructure classifications  
Schipropins A-J, structurally diverse triterpenoids from Schisandra propinqua 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 182, 页码: 112589
Authors:  Ma,Ren-Fen;  Hu,Kun;  Ding,Wen-Ping;  Wang,Bin;  He,Tao-Bin;  Li,Xiao-Nian;  Sun,Han-Dong;  Puno,Pema-Tenzin
View  |  Adobe PDF(2549Kb)  |  Favorite  |  View/Download：327/66  |  Submit date：2022/04/02
Schisandra propinqua  Lanostane-type triterpenoids  Cycloartane-type triterpenoids  Cytotoxicity  Anti-inflammation  NORTRITERPENOIDS  LIGNANS  SKELETON  
C-19 Benzylisoquinoline Alkaloid with Unprecedented Architecture from Hypecoum erectum 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 23, 页码: 16764-16769
Authors:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Hu,Kun;  He,Ying-Jie;  Yang,Xing-Wei;  Luo,Xiao-Dong
View  |  Adobe PDF(1336Kb)  |  Favorite  |  View/Download：201/64  |  Submit date：2022/04/02
OPIUM POPPY  BIOSYNTHESIS  APORPHINE  TETRANDRINE  PAPAVERINE  DISCOVERY  
Neuroprotective schinortriterpenoids from Schisandra neglecta collected in Medog County, Tibet, China 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104785
Authors:  Wang,Bin;  Hu,Kun;  Li,Xiao-Nian;  Sun,Han-Dong;  Qin,Hong-Bo;  Puno,Pema-Tenzin
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Schisandra neglecta  16  17-secopreschisanartane-type  schinortriterpenoids  Schisdilactones K?U  Quantum chemical calculation  Neuroprotective activity  DIBENZOCYCLOOCTADIENE LIGNANS  NORTRITERPENOIDS  CHINENSIS  STEMS  7,8-SECOLIGNANS  TRITERPENOIDS