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Anti-NLRP3 inflammasome abietane diterpenoids from Callicarpa bodinieri and their structure elucidation 期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 2, 页码: 427-430
作者:  Gao, Junbo;  Zhang, Xingjie;  Shang, Kun;  Zhong, Weimao;  Zhang, Ruihan;  Dai, Xiaochang;  Li, Xiaoli;  Wang, Qi;  Zou, Yan;  Xiao, Weilie
收藏  |  浏览/下载：145/0  |  提交时间：2020/03/24
Callicarpa bodinieri  Abietane-type diterpenoids  DP4+NMR calculation  Anti-inflammation  Pyroptosis  NLRP3 inflammasome  
Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10
作者:  Li, Penghua;  He, Haiqing;  Zhang, Yunqin;  Yang, Rui;  Xu, Lili;  Chen, Zixi;  Huang, Yingying;  Bao, Limei;  Xiao, Guozhi
收藏  |  浏览/下载：92/0  |  提交时间：2020/03/24
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：153/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Exploring Aporphine as Anti-inflammatory and Analgesic Lead from Dactylicapnos scandens 期刊论文
ORGANIC LETTERS, 2020, 卷号: 22, 期号: 1, 页码: 257-260
作者:  Wang, Bei;  Zhao, Yin-Jiao;  Zhao, Yun-Li;  Liu, Ya-Ping;  Li, Xiao-Nian;  Zhang, Hongbin;  Luo, Xiao-Dong
收藏  |  浏览/下载：123/0  |  提交时间：2020/03/18
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
Adobe PDF(2215Kb)  |  收藏  |  浏览/下载：186/50  |  提交时间：2020/03/18
Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
作者:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
浏览  |  Adobe PDF(1542Kb)  |  收藏  |  浏览/下载：255/73  |  提交时间：2020/03/18
delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：173/29  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 22, 页码: 9272-9275
作者:  Zhang, Yu;  Ding, Xiao;  Shao, Shun;  Guo, Ling-Li;  Zhao, Qing;  Hao, Xiao-Jiang;  He, Hong-Ping
浏览  |  Adobe PDF(982Kb)  |  收藏  |  浏览/下载：273/153  |  提交时间：2020/03/02
Design and synthesis of novel artemisinin derivatives with potent activities against colorectal cancer in vitro and in vivo 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 10
作者:  Wang, Liang-Liang;  Kong, Lingmei;  Liu, Hui;  Zhang, Yunqin;  Zhang, Li;  Liu, Xingyong;  Yuan, Feng;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：115/0  |  提交时间：2020/03/02
Artemisinin  Quinazoline  Hybridization  Colorectal cancer  Chemotherapy  
Flavipesines A and B and Asperchalasines E-H: Cytochalasans and Merocytochalasans from Aspergillus flavipes 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 11, 页码: 2994-3001
作者:  Zhang, Xiaotian;  Yang, Lu;  Wang, Wenjing;  Wu, Zhaodi;  Wang, Jianping;  Sun, Weiguang;  Li, Xiao-Nian;  Chen, Chunmei;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1885Kb)  |  收藏  |  浏览/下载：116/22  |  提交时间：2020/03/18