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Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 11, 页码: 4680-4692
作者:  Qu, Chunrong;  Ding, Mingmin;  Zhu, Yingmin;  Lu, Yungang;  Du, Juan;  Miller, Melissa;  Tian, Jinbin;  Zhu, Jinmei;  Xui, Jian;  Wen, Meng;  Er-Bu, Aga;  Wan, Jule;  Xiao, Yuling;  Wu, Meng;  McManus, Owen B.;  Li, Min;  Wu, Jilin;  Luo, Huai-Rong;  Cao, Zhengyu;  Shen, Bing;  Wang, Hongbo;  Zhu, Michael X.;  Hong, Xuechuan
Adobe PDF(1969Kb)  |  收藏  |  浏览/下载：202/77  |  提交时间：2017/08/29
Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way 期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2017, 卷号: 426, 期号: 1-2, 页码: 101-109
作者:  Ding, Ai-Jun;  Wu, Gui-Sheng;  Tang, Bin;  Hong, Xuechuan;  Zhu, Michael X.;  Luo, Huai-Rong
Adobe PDF(557Kb)  |  收藏  |  浏览/下载：241/80  |  提交时间：2017/05/19
Aging  Benzimidazole Derivative M084  Caenorhabditis Elegans  Lifespan  
Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 8
作者:  Yang, Li-Ping;  Jiang, Fang-Jie;  Wu, Gui-Sheng;  Deng, Ke;  Wen, Meng;  Zhou, Xiaoju;  Hong, Xuechuan;  Zhu, Michael X.;  Luo, Huai-Rong
Adobe PDF(1207Kb)  |  收藏  |  浏览/下载：225/74  |  提交时间：2016/01/19
Triterpenoids with Promoting Effects on the Differentiation of PC12 Cells from the Steamed Roots of Panax notoginseng 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2015, 卷号: 78, 期号: 8, 页码: 1829-1840
作者:  Gu, Cheng-Zhen;  Lv, Jun-Jiang;  Zhang, Xiao-Xia;  Qiao, Yi-Jun;  Yan, Hui;  Li, Yan;  Wang, Dong;  Zh, Hong-Tao;  Luo, Huai-Rong;  Yang, Chong-Ren;  Xu, Min;  Zhang, Ying-Jun
Adobe PDF(1081Kb)  |  收藏  |  浏览/下载：316/110  |  提交时间：2016/01/19
Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2015, 卷号: 172, 期号: 14, 页码: 3495-3509
作者:  Zhu, Yingmin;  Lu, Yungang;  Qu, Chunrong;  Miller, Melissa;  Tian, Jinbin;  Thakur, Dhananjay P.;  Zhu, Jinmei;  Deng, Zixin;  Hu, Xianming;  Wu, Meng;  McManus, Owen B.;  Li, Min;  Hong, Xuechuan;  Zhu, Michael X.;  Luo, Huai-Rong
Adobe PDF(2298Kb)  |  收藏  |  浏览/下载：188/46  |  提交时间：2015/12/15
Minor dehydrogenated and cleavaged dammarane-type saponins from the steamed roots of Panax notoginseng 期刊论文
FITOTERAPIA, 2015, 卷号: 103, 页码: 97-105
作者:  Gu, Cheng-Zhen;  Lv, Jun-Jiang;  Zhang, Xiao-Xia;  Yan, Hui;  Zhu, Hong-Tao;  Luo, Huai-Rong;  Wang, Dong;  Yang, Chong-Ren;  Xu, Min;  Zhang, Ying-Jun
Adobe PDF(467Kb)  |  收藏  |  浏览/下载：242/102  |  提交时间：2015/12/15
Panax Notoginseng  Triterpenoid Saponins  Pc12 Cells  
Nortriterpenoids from Schisandra chinensis and their absolute configurational assignments by electronic circular dichroism study 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 4, 页码: 859-868
作者:  Shi, Yi-Ming;  Wang, Li-Yan;  Zou, Xi-Sheng;  Li, Xiao-Nian;  Shang, Shan-Zhai;  Gao, Zhong-Hua;  Liang, Cheng-Qin;  Luo, Huai-Rong;  Li, Hong-Lin;  Xiao, Wei-Lie;  Sun, Han-Dong
Adobe PDF(1553Kb)  |  收藏  |  浏览/下载：551/61  |  提交时间：2014/04/09
Schisandra  Schisandra Chinensis  Nortriterpenoid  Electronic Circular Dichroism  Absolute Configuration  
吡唑并嘧啶类化合物及其药物组合物和其在制药中的应用 专利
专利类型: 发明, 专利号: CN201310666552.1, 申请日期: 2013-12-10, 公开日期: 2014-04-02
发明人:  罗怀容;  洪学传;  朱曦;  朱进妹;  吴桂生;  邓子新;  朱颖旻;  陆云刚;  邓科;  瞿春容
Adobe PDF(1569Kb)  |  收藏  |  浏览/下载：432/6  |  提交时间：2016/12/19
Synthesis and neurotrophic activity evaluation of amaryllidaceae alkaloids 期刊论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 卷号: 246
作者:  Luo, Huairong;  He, Maomao;  Zhu, Jinmei;  Wu, Chunfeng;  Deng, Zixin;  Hong, Xuechuan
收藏  |  浏览/下载：226/0  |  提交时间：2015/05/14
Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 14, 页码: 4218-4224
作者:  Zhu, Jinmei;  Wu, Chun-Feng;  Li, Xiaobing;  Wu, Gui-Sheng;  Xie, Shan;  Hu, Qian-Nan;  Deng, Zixin;  Zhu, Michael X.;  Luo, Huai-Rong;  Hong, Xuechuan
Adobe PDF(1174Kb)  |  收藏  |  浏览/下载：529/89  |  提交时间：2013/10/16
Alzheimer's Disease  Acetylcholinesterase  Butyrylcholinesterase  Molecular Modeling  2-aminobenzimidazole