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Nonasaccharide Inhibits Intrinsic Factor Xase Complex by Binding to Factor IXa and Disrupting Factor IXa-Factor VIIIa Interactions 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 期号: 5, 页码: 705-715
作者:  Xiao, Chuang;  Zhao, Longyan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(740Kb)  |  收藏  |  浏览/下载：199/52  |  提交时间：2019/06/24
nonasaccharide from fucosylated glycosaminoglycan  intrinsic factor Xase complex  factor IXa  anticoagulant  
Synthesis of Fucosylated Chondroitin Sulfate Nonasaccharide as a Novel Anticoagulant Targeting Intrinsic Factor Xase Complex 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 39, 页码: 12880-12885
作者:  Zhang, Xiao;  Liu, Huiying;  Lin, Lisha;  Yao, Wang;  Zhao, Jinhua;  Wu, Mingyi;  Li, Zhongjun
浏览  |  Adobe PDF(1568Kb)  |  收藏  |  浏览/下载：200/51  |  提交时间：2018/10/22
Anticoagulants  Drug Discovery  Fucosylated Chondroitin Sulfate  Glycosaminoglycans  Oligosaccharides  
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
作者:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(1313Kb)  |  收藏  |  浏览/下载：199/29  |  提交时间：2018/10/07
Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis  
Structural analysis and anticoagulant activities of three highly regular fucan sulfates as novel intrinsic factor Xase inhibitors 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 195, 页码: 257-266
作者:  Shang, Feineng;  Mou, Rongrong;  Zhang, Zhidong;  Gao, Na;  Lin, Lisha;  Li, Zhongkun;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(2021Kb)  |  收藏  |  浏览/下载：311/58  |  提交时间：2018/07/16
Fucan Sulfate  Chemical Structure  Anticoagulant  Polysaccharide  Sea Cucumber  
An anticoagulant fucan sulfate with hexasaccharide repeating units from the sea cucumber Holothuria albiventer 期刊论文
CARBOHYDRATE RESEARCH, 2018, 卷号: 464, 页码: 12-18
作者:  Cai, Ying;  Yang, Wenjiao;  Yin, Ronghua;  Zhou, Lutan;  Li, Zhongkun;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(4007Kb)  |  收藏  |  浏览/下载：270/41  |  提交时间：2018/07/16
Fucan Sulfate  Chemical Structure  Anticoagulant  Polysaccharide  Sea Cucumber  
Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 423-435
作者:  Shang, Feineng;  Gao, Na;  Yin, Ronghua;  Lin, Lisha;  Xiao, Chuang;  Zhou, Lutan;  Li, Zi;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(3117Kb)  |  收藏  |  浏览/下载：234/70  |  提交时间：2018/05/08
Glycosaminoglycan  Oligosaccharide  Anticoagulant  Intrinsic Factor Xase  
Synthesis of Fucosylated Chondroitin Sulfate Glycoclusters: A Robust Route to New Anticoagulant Agents 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2018, 卷号: 24, 期号: 7, 页码: 1694-1700
作者:  Zhang, Xiao;  Yao, Wang;  Xu, Xiaojiang;  Sun, Huifang;  Zhao, Jinhua;  Meng, Xiangbao;  Wu, Mingyi;  Li, Zhongjun
浏览  |  Adobe PDF(1719Kb)  |  收藏  |  浏览/下载：171/47  |  提交时间：2018/05/08
Anticoagulants  Drug Discovery  Glycoconjugates  Structure-activity Relationships  Synthesis Design  
Structural analysis and biological activity of a highly regular glycosaminoglycan from Achatina fulica 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 181, 页码: 433-441
作者:  Liu, Jie;  Zhou, Lutan;  He, Zhicheng;  Gao, Na;  Shang, Feineng;  Xu, Jianping;  Li, Zi;  Yang, Zengming;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(2955Kb)  |  收藏  |  浏览/下载：265/60  |  提交时间：2018/05/08
Snail  Glycosaminoglycan  Chemical Structure  Heparin  Anticoagulant  
Plasma contact activation by a fucosylated chondroitin sulfate and its structure-activity relationship study 期刊论文
GLYCOBIOLOGY, 2018, 卷号: 28, 期号: 10, 页码: 754-764
作者:  Lin, Lisha;  Xu, Li;  Xiao, Chuang;  Zhou, Lutan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(595Kb)  |  收藏  |  浏览/下载：160/37  |  提交时间：2019/03/29
Modulating the degree of fucosylation of fucosylated chondroitin sulfate enhances heparin cofactor II-dependent thrombin inhibition 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154, 页码: 133-143
作者:  Xu, Li;  Gao, Na;  Xiao, Chuang;  Lin, Lisha;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(7486Kb)  |  收藏  |  浏览/下载：127/40  |  提交时间：2019/03/29