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Two new prenylated C-6-C-3 compounds from Illicium micranthum Dunn 期刊论文
NATURAL PRODUCT RESEARCH, 2020, 卷号: 34, 期号: 3, 页码: 425-428
作者:  Liu, Lu;  Lv, Xiao-Man;  Hua, Tian;  Khan, Afsar;  Huang, Xiao-Bing;  Wang, Yi-Fen;  Zhou, Zhi-Hong
收藏  |  浏览/下载：126/0  |  提交时间：2020/03/18
Illicium micranthum  prenylated C6-C3 compounds  sesquiterpene lactone  acetylcholinesterase  
Cangumycins A-F, six new angucyclinone analogues with immunosuppressive activity from Streptomyces 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 982-987
作者:  Wang Lei;  Wang Li;  Zhou Zhi;  Wang Yong-Jiang;  Huang Jian-Ping;  Ma Ya-Tuan;  Liu Yang;  Huang Sheng-Xiong
浏览  |  Adobe PDF(563Kb)  |  收藏  |  浏览/下载：130/31  |  提交时间：2020/03/18
Streptomyces  Angucyclinones  Benz[a]anthracenes  Natural products  Immunosuppressive activity  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：162/28  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
作者:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
浏览  |  Adobe PDF(4714Kb)  |  收藏  |  浏览/下载：289/39  |  提交时间：2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Phlegmadine A: A Lycopodium Alkaloid with a Unique Cyclobutane Ring from Phlegmariurus phlegmaria 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 84, 期号: 17, 页码: 11301-11305
作者:  Zhang, Zhi-Jun;  Wang, Chen;  Wu, Xing-De;  Huang, Yan;  Zhou, Wen-Xia;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1540Kb)  |  收藏  |  浏览/下载：136/20  |  提交时间：2019/11/07
Discovery of novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by virtual screening 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78, 页码: 306-316
作者:  Zhou, Yeheng;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Li, Yingying;  Zhang, Li;  Sun, Wei;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(2732Kb)  |  收藏  |  浏览/下载：227/42  |  提交时间：2019/03/25
IDO1  Molecular docking  HipHop pharmacophore  3D-QSAR  PAINS  
Glucoside Derivatives Of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 3683-3692
作者:  Zi, Cheng-Ting;  Yang, Liu;  Kong, Qing-Hua;  Li, Hong-Mei;  Yang, Xing-Zhi;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao;  Zhou, Jun
浏览  |  Adobe PDF(3776Kb)  |  收藏  |  浏览/下载：137/18  |  提交时间：2020/03/26
podophyllotoxin  glucoside  synthesis  cytotoxicity  physicochemical properties  
Pharmacophore modeling, molecular docking and molecular dynamics simulations toward identifying lead compounds for Chk1 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 卷号: 76, 页码: 53-60
作者:  Li, Yaping;  Peng, Jiale;  Zhou, Yeheng;  Li, Penghua;  Li, Yingying;  Liu, Xingyong;  Siddique, Abu Nasar;  Zhang, Li;  Zuo, Zhili
收藏  |  浏览/下载：125/0  |  提交时间：2018/11/12
Checkpoint kinase 1 inhibitor  Virtual screening  Pharmacophore modeling  Molecular docking  Molecular dynamics simulations  
苄烯叉苯肽类化合物及其药物组合物和其应用 专利
申请日期: 2018-05-16, 公开日期: 2018-11-06
发明人:  左之利;  孙威;  彭佳乐;  孔德信;  周业珩
收藏  |  浏览/下载：70/0  |  提交时间：2019/08/14
Structure-Activity Relationship of Xanthones as Inhibitors of Xanthine Oxidase 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 2, 页码: 365
作者:  Zhou, Ling-Yun;  Peng, Jia-Le;  Wang, Jun-Ming;  Geng, Yuan-Yuan;  Zuo, Zhi-Li;  Hua, Yan
浏览  |  Adobe PDF(2334Kb)  |  收藏  |  浏览/下载：173/38  |  提交时间：2018/05/08
Xanthone  Xanthine Oxidase Inhibitors  3d-qsar  Gout