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Discovery of diverse sesquiterpenoids from Magnolia grandiflora with cytotoxic activities by inducing cell apoptosis 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 106707
作者:  Xu,Shuangyu;  Tang,Yunyan;  Li,Yanan;  Yang,Jue;  Gu,Wei;  Hao,Xiaojiang;  Yuan,Chunmao
浏览  |  Adobe PDF(5040Kb)  |  收藏  |  浏览/下载：195/42  |  提交时间：2024/07/22
Magnolia grandiflora  Sesquiterpenoids  Isolation and structural modification  Cytotoxic activity  Apoptosis  LACTONES  DERIVATIVES  LEAVES  AGENTS  
Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 9, 页码: 8113
作者:  Xu,Xinglian;  Deng,Lulu;  Tang,Yaling;  Li,Jiang;  Zhong,Ting;  Hao,Xiaojiang;  Fan,Yanhua;  Mu,Shuzhen
浏览  |  Adobe PDF(5829Kb)  |  收藏  |  浏览/下载：213/26  |  提交时间：2024/05/09
leukemia  sanguinarine  c-MET  MAPK  PI3K/mTOR  STAT3  MET  
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
作者:  Ran,Xiaoqian;  Lu,Qing-Yun;  Li,Ying-Yao;  Pu,Xue-Xue;  Guo,Yarong;  Yuan,Ming-Rui;  Guan,Shi-Peng;  Sun,Mao;  Jiao,Lijin;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang;  Luo,Rongcan
浏览  |  Adobe PDF(10283Kb)  |  收藏  |  浏览/下载：195/54  |  提交时间：2024/07/30
Euphorbia peplus L  Euphorbiaceae  Ent-abietane diterpenoid  Euphejolkinolide A  Autophagy-lysosomal pathway  ALZHEIMERS-DISEASE  TAU PATHOLOGY  NEURODEGENERATION  DITERPENOIDS  INHIBITION  MECHANISMS  APOPTOSIS  CELASTROL  PROTEIN  SYSTEM  
Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway 期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
作者:  Yang,Hao-Jie;  Li,Ya-Nan;  Yan,Chen;  Yang,Jue;  Zeng,Yan-Rong;  Yi,Ping;  Li,Yan-Mei;  Hao,Xiao-Jiang;  Yuan,Chun-Mao
浏览  |  Adobe PDF(2804Kb)  |  收藏  |  浏览/下载：206/63  |  提交时间：2022/04/02
Dysoxylum gotadhora  Rocaglaol derivatives  HCT116  Cytotoxic activity  MAPK pathway  FLAVAGLINES  
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
作者:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
浏览  |  Adobe PDF(2105Kb)  |  收藏  |  浏览/下载：303/116  |  提交时间：2022/04/02
Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA  
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 卷号: 17, 期号: 11, 页码: 2703-2717
作者:  Wei,Ruiran;  Zhao,Yueqin;  Wang,Juan;  Yang,Xu;  Li,Shunlin;  Wang,Yinyuan;  Yang,Xingzhi;  Fei,Jimin;  Hao,Xiaojiang;  Zhao,Yuhan;  Gui,Liming;  Ding,Xiao
浏览  |  Adobe PDF(9123Kb)  |  收藏  |  浏览/下载：310/44  |  提交时间：2022/04/02
Ferroptosis  Tagitinin c  Ros  Er Stress  Nrf2-ho-1 Pathway  Endoplasmic-reticulum Stress  Er-stress  Oxidative Stress  Tumor-suppressor  Nrf2  Death  Iron  Differentiation  Mechanisms  Resistance  
Sesquiterpene lactones from Carpesium abrotanoides L. and their activity in inducing protective autophagy 期刊论文
NATURAL PRODUCT RESEARCH, 2021
作者:  Yang,Bao-Jia;  Wang,Juan;  Zeng,Zheng-Quan;  Yang,Xu;  Huang,Ai-Ying;  Hao,Xiao-Jiang;  Ding,Xiao;  Li,Shun-Lin
收藏  |  浏览/下载：185/0  |  提交时间：2022/04/02
Carpesium abrotanoides L  sesquiterpene lactone  autophagy  lysosomal biogenesis  cytotoxic activity  
Natural product sciences: an integrative approach to the innovations of plant natural products 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2020
作者:  Shen, Yuemao;  Hao, Xiaojiang
浏览  |  Adobe PDF(4992Kb)  |  收藏  |  浏览/下载：269/33  |  提交时间：2021/01/05
Aphananoid A is an Anti-Inflammatory Limonoid with a New 5/6/5 Fused Ring Featuring a C-24 Carbon Skeleton from Aphanamixis polystachya 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2020
作者:  Yang, Bi-Juan;  Fan, Shi-Rui;  Cai, Jie-Yun;  Wang, Yi-Ting;  Jing, Chen-xu;  Guo, Jing-Jing;  Chen, Duo-Zhi;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1960Kb)  |  收藏  |  浏览/下载：438/62  |  提交时间：2021/01/05
Two new bioactive lignans from leaves and twigs of Cleistanthus concinnus Croizat 期刊论文
NATURAL PRODUCT RESEARCH, 2020
作者:  Fan, Shi-rui;  Guo, Jing-jing;  Wang, Yi-ting;  Yang, Bi-juan;  Chen, Duo-zhi;  Hao, Xiao-jiang
浏览  |  Adobe PDF(944Kb)  |  收藏  |  浏览/下载：268/91  |  提交时间：2021/01/05