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Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N-9-Methyl Group in the Conformation and Bioactivity 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 12
作者:  Wang, Zhe;  Zhao, Si-Meng;  Zhao, Li-Mei;  Chen, Xiao-Qiang;  Zeng, Guang-Zhi;  Tan, Ning-Hua
浏览  |  Adobe PDF(805Kb)  |  收藏  |  浏览/下载:690/180  |  提交时间:2016/02/01
Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 8
作者:  Yang, Li-Ping;  Jiang, Fang-Jie;  Wu, Gui-Sheng;  Deng, Ke;  Wen, Meng;  Zhou, Xiaoju;  Hong, Xuechuan;  Zhu, Michael X.;  Luo, Huai-Rong
浏览  |  Adobe PDF(1207Kb)  |  收藏  |  浏览/下载:215/70  |  提交时间:2016/01/19
Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 5, 页码: e0127092
作者:  Liu, Yanchun;  Yang, Hui;  Chen, Tianxing;  Luo, Yongbin;  Xu, Zheyuan;  Li, Ying;  Yang, Jiahui;  Yang,JH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming,Yunnan,Peoples R China.;  yangjiahui@mail.kib.ac.cn
Adobe PDF(1997Kb)  |  收藏  |  浏览/下载:244/71  |  提交时间:2015/07/20
Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 7, 页码: e103760
作者:  Kong, Yanjie;  Chen, Jianchao;  Zhou, Zhongmei;  Xia, Houjun;  Qiu, Ming-Hua;  Chen, Ceshi;  Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming,Yunnan,Peoples R China.;  qiuminghua@mail.kib.ac.cn;  chenc@mail.kiz.ac.cn
Adobe PDF(3184Kb)  |  收藏  |  浏览/下载:184/37  |  提交时间:2014/11/25
Inhibitory-activity  Signaling Pathway  Carcinoma  Growth  Activation  
The Apoptotic Effect of D Rhamnose beta-Hederin, a Novel Oleanane-Type Triterpenoid Saponin on Breast Cancer Cells 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 3, 页码: e90848
作者:  Cheng, Lin;  Xia, Tian-Song;  Wang, Yi-Fen;  Zhou, Wenbin;  Liang, Xiu-Qing;  Xue, Jin-Qiu;  Shi, Liang;  Wang, Ying;  Ding, Qiang
Adobe PDF(4818Kb)  |  收藏  |  浏览/下载:280/73  |  提交时间:2014/05/16
Oxygen Species Generation  Bcl-2 Family Proteins  Platycodon-grandiflorum  Ginsenoside Rh2  Hepatoma-cells  Mapk Pathways  Anticancer  Activation  Induction  Death  
Plastid Genome Sequence of a Wild Woody Oil Species, Prinsepia utilis, Provides Insights into Evolutionary and Mutational Patterns of Rosaceae Chloroplast Genomes 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 9
作者:  Wang, Shuo;  Shi, Chao;  Gao, Li-Zhi
浏览  |  Adobe PDF(1968Kb)  |  收藏  |  浏览/下载:598/82  |  提交时间:2013/10/16
Phylogenetic-relationships  Maximum-likelihood  Dna  Angiosperms  Microsatellites  Generation  Regions  Markers  Population  Expansion  
Trichothecin Induces Cell Death in NF-kappa B Constitutively Activated Human Cancer Cells via Inhibition of IKK beta Phosphorylation 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e71333
作者:  Su, Jia;  Zhao, Peiji;  Kong, Lingmei;  Li, Xingyao;  Yan, Juming;  Zeng, Ying;  Li, Yan
Adobe PDF(1124Kb)  |  收藏  |  浏览/下载:299/55  |  提交时间:2013/11/12
Colitis-associated Cancer  Multiple-myeloma Cells  P65 Phosphorylation  Endophytic Fungus  Kinase-activity  Tumor-growth  In-vitro  Pathway  Apoptosis  Inflammation  
Acetylcholineestarase-Inhibiting Alkaloids from Lycoris radiata Delay Paralysis of Amyloid Beta-Expressing Transgenic C. elegans CL4176 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 5, 页码: e63874
作者:  Xin, Lijuan;  Yamujala, Ritupriya;  Wang, Yuehu;  Wang, Huan;  Wu, Wen-Hsuan;  Lawton, Michael A.;  Long, Chunlin;  Di, Rong
浏览  |  Adobe PDF(760Kb)  |  收藏  |  浏览/下载:316/71  |  提交时间:2013/07/24
Alzheimers-disease  Caenorhabditis-elegans  Acetylcholinesterase Inhibitors  Amaryllidaceae Alkaloids  Oxidative Stress  Pc12 Cells  Peptide  Genes  Peroxide  Hypothesis  
Drug Absorption Efficiency in Caenorhbditis elegans Delivered by Different Methods 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 2, 页码: e56877
作者:  Zheng, Shan-Qing;  Ding, Ai-Jun;  Li, Guo-Ping;  Wu, Gui-Sheng;  Luo, Huai-Rong
浏览  |  Adobe PDF(794Kb)  |  收藏  |  浏览/下载:653/82  |  提交时间:2013/07/24
Adult Caenorhabditis-elegans  Life-span  Caloric Restriction  Dietary Restriction  Mass-spectrometry  Small Molecules  C. Elegans  Resveratrol  Model  Identification  
alpha-Mangostin Induces Apoptosis and Suppresses Differentiation of 3T3-L1 Cells via Inhibiting Fatty Acid Synthase 期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 3, 页码: e33376
作者:  Quan, Xiaofang;  Wang, Yi;  Ma, Xiaofeng;  Liang, Yan;  Tian, Weixi;  Ma, Qingyun;  Jiang, Hezhong;  Zhao, Youxing
Adobe PDF(767Kb)  |  收藏  |  浏览/下载:405/168  |  提交时间:2012/06/07
Aconitum Transsectum  Diterpenoid Alkaloids  Aconitramines d And e  Norditerpenoid Alkaloids