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Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
Adobe PDF(5724Kb)  |  收藏  |  浏览/下载:366/41  |  提交时间:2017/12/18
Sauruchinenols A and B, unprecedented monocyclic diterpenes with new carbon skeleton from the aerial parts of Saururus chinensis 期刊论文
FITOTERAPIA, 2017, 卷号: 116, 页码: 116-120
作者:  Gao, Xiu;  He, Juan;  Wu, Xing-De;  Peng, Li-Yan;  Shao, Li-Dong;  Li, Yan;  Cheng, Xiao;  Zhao, Qin-Shi
Adobe PDF(503Kb)  |  收藏  |  浏览/下载:282/37  |  提交时间:2017/04/18
Saururus Chinensis  Saururaceae  Sauruchinenols A-d  Anti-no Production  
Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum 期刊论文
FITOTERAPIA, 2016, 卷号: 109, 页码: 224-229
作者:  He, Juan;  Peng, Li-Yan;  Tu, Lin;  Wu, Xing-De;  Dong, Liao-Bing;  Pan, Zheng-Hong;  Chen, Xuan-Qin;  Su, Jia;  Zhao, Yu;  Xu, Gang;  Cheng, Xiao;  Li, Yan;  Zhao, Qin-Shi
浏览  |  Adobe PDF(446Kb)  |  收藏  |  浏览/下载:248/81  |  提交时间:2016/08/22
Viburnum Odoratissimum  Vibsane-type Diterpenes  Vibsanols C-h  Vibsanin x  Cytotoxicity  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载:266/68  |  提交时间:2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Vincamajorines A and B, monoterpenoid indole alkaloids with new carbon skeletons from Vinca major 期刊论文
TETRAHEDRON LETTERS, 2014, 卷号: 55, 期号: 47, 页码: 6490-6494
作者:  Zhang, Zhi-Jun;  Yang, Jing;  He, Juan;  Wu, Xing-De;  Shao, Li-Dong;  Li, Yan;  Huang, Sheng-Xiong;  Li, Rong-Tao;  Zhao, Qin-Shi;  Li,RT (reprint author),Kunming Univ Sci & Technol,Fac Life Sci & Technol,Chenggong Campus,Kunming 650050,Yunnan,Peoples R China.;  rongtaolikm@163.com;  qinshizhao@mail.kib.ac.cn
Adobe PDF(763Kb)  |  收藏  |  浏览/下载:295/72  |  提交时间:2015/01/20
Vinca Major  Monoterpenoid Indole Alkaloids  Quantum Chemical Calculations  
New alkaloids sinomacutines A-E, and cephalonine-2-O-beta-D-glucopyranoside from rhizomes of Sinomenium acutum 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 46, 页码: 8893-8899
作者:  Li, Yan-Hong;  Li, Hong-Mei;  Li, Yan;  He, Juan;  Deng, Xu;  Peng, Li-Yan;  Gao, Ling-Huan;  Zhao, Qin-Shi;  Li, Rong-Tao;  Wu, Xing-De;  Li,RT (reprint author),Kunming Univ Sci & Technol,Fac Life Sci & Technol,Kunming 650500,Yunnan,Peoples R China.;  rongtaolikm@gmail.com;  wuxingde@mail.kib.ac.cn
Adobe PDF(673Kb)  |  收藏  |  浏览/下载:256/69  |  提交时间:2015/01/20
Sinomenium Acutum  Bistetrahydroisoquinoline Alkaloid  Acid Hydrolysis  Cytotoxicity  Anti-inflammatory Activity  
Evollionines A - C, Three New Alkaloids Isolated from the Fruits of Evodia rutaecarpa 期刊论文
HELVETICA CHIMICA ACTA, 2014, 卷号: 97, 期号: 11, 页码: 1481-1486
作者:  Li, Yan-Hong;  He, Juan;  Li, Yan;  Wu, Xing-De;  Peng, Li-Yan;  Du, Ru-Nan;  Cheng, Xiao;  Zhao, Qin-Shi;  Li, Rong-Tao;  Zhao,QS (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  qinshizhao@mail.kib.ac.cn;  rongtaolikm@gmail.com
Adobe PDF(218Kb)  |  收藏  |  浏览/下载:490/157  |  提交时间:2015/01/20
Isolated Major Compounds  Prostate-cancer  In-vitro  Triterpenoids  Proliferation  Glycosides  Apoptosis  Leaf  
A New Quinolizidine Alkaloid from Sophora flavescens 期刊论文
CHEMISTRY OF NATURAL COMPOUNDS, 2014, 卷号: 50, 期号: 5, 页码: 876-879
作者:  Wang Lei;  Wu Xing-De;  He Juan;  Li Gen-Tao;  Peng Li-Yan;  Li Yan;  Song Liu-Dong;  Zhao Qin-Shi;  Wang,L (reprint author),Kunming Med Univ,Sch Pharmaceut Sci,Kunming 650500,Peoples R China.;  ynsld@126.com;  qinshizhao@mail.kib.ac.cn
浏览  |  Adobe PDF(165Kb)  |  收藏  |  浏览/下载:298/114  |  提交时间:2015/01/20
Sophora Flavescens  Leguminosae  Alkaloids  Cytotoxicity  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
Adobe PDF(1971Kb)  |  收藏  |  浏览/下载:667/101  |  提交时间:2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Three new abietane diterpenoids from Podocarpus fleuryi 期刊论文
PHYTOCHEMISTRY LETTERS, 2013, 卷号: 6, 期号: 3, 页码: 364-367
作者:  Zhang, Lan-Chun;  Wu, Xing-De;  He, Juan;  Li, Yan;  Zhang, Rong-Ping;  Zhao, Qin-Shi
Adobe PDF(389Kb)  |  收藏  |  浏览/下载:286/82  |  提交时间:2013/10/16
Podocarpus Fleuryi  Diterpenoids  Fleuryinols A-c  Cytotoxic Activity