Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum
He, Juan1; Peng, Li-Yan1; Tu, Lin1; Wu, Xing-De1; Dong, Liao-Bing1; Pan, Zheng-Hong2; Chen, Xuan-Qin3; Su, Jia1; Zhao, Yu1; Xu, Gang1; Cheng, Xiao1; Li, Yan1; Zhao, Qin-Shi1
2016-03-01
Source PublicationFITOTERAPIA
Volume109Pages:224-229
AbstractSeven new vibsane-type diterpenes, vibsanols C-H (1-6) and vibsanin X (7), together with seven analogues, were isolated from the leaves and twigs of Viburnum odoratissimum. The structures of the new compounds were 'elucidated by extensive spectroscopic methods. All the new compounds were detected for their cytotoxicity. Compound 1 showed significant cytotoxicity against all the tested cell lines (HL-60, SMMC-7721, A-594, MCF7, and SW-480), with IC50 values of 3.35, 4.41, 5.18,1130, and 3.70 M, respectively. Compounds 4 and 5 also displayed significant cytotoxicity against hepatocellular carcinoma SMMC-7721 cell line, with IC50 values of 3.69 and 3.52 M, respectively. (C) 2016 Elsevier B.V. All rights reserved.
KeywordViburnum Odoratissimum Vibsane-type Diterpenes Vibsanols C-h Vibsanin x Cytotoxicity
DOI10.1016/j.fitote.2016.01.014
Indexed BySCI
Language英语
WOS IDWOS:000372685400036
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/26193
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Guangxi Inst Bot, Guilin 541006, Peoples R China
3.Kunming Univ Sci & Technol, Kunming 650093, Peoples R China
Recommended Citation
GB/T 7714
He, Juan,Peng, Li-Yan,Tu, Lin,et al. Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum[J]. FITOTERAPIA,2016,109:224-229.
APA He, Juan.,Peng, Li-Yan.,Tu, Lin.,Wu, Xing-De.,Dong, Liao-Bing.,...&Zhao, Qin-Shi.(2016).Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum.FITOTERAPIA,109,224-229.
MLA He, Juan,et al."Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum".FITOTERAPIA 109(2016):224-229.
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