| Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum | |
He, Juan1; Peng, Li-Yan1; Tu, Lin1; Wu, Xing-De1; Dong, Liao-Bing1; Pan, Zheng-Hong2; Chen, Xuan-Qin3; Su, Jia1; Zhao, Yu1; Xu, Gang1 ; Cheng, Xiao1; Li, Yan1; Zhao, Qin-Shi1
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| 2016-03-01 | |
| 发表期刊 | FITOTERAPIA
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| 卷号 | 109页码:224-229 |
| 摘要 | Seven new vibsane-type diterpenes, vibsanols C-H (1-6) and vibsanin X (7), together with seven analogues, were isolated from the leaves and twigs of Viburnum odoratissimum. The structures of the new compounds were 'elucidated by extensive spectroscopic methods. All the new compounds were detected for their cytotoxicity. Compound 1 showed significant cytotoxicity against all the tested cell lines (HL-60, SMMC-7721, A-594, MCF7, and SW-480), with IC50 values of 3.35, 4.41, 5.18,1130, and 3.70 M, respectively. Compounds 4 and 5 also displayed significant cytotoxicity against hepatocellular carcinoma SMMC-7721 cell line, with IC50 values of 3.69 and 3.52 M, respectively. (C) 2016 Elsevier B.V. All rights reserved. |
| 关键词 | Viburnum Odoratissimum Vibsane-type Diterpenes Vibsanols C-h Vibsanin x Cytotoxicity |
| DOI | 10.1016/j.fitote.2016.01.014 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000372685400036 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/26193 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Guangxi Inst Bot, Guilin 541006, Peoples R China 3.Kunming Univ Sci & Technol, Kunming 650093, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Juan,Peng, Li-Yan,Tu, Lin,et al. Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum[J]. FITOTERAPIA,2016,109:224-229. |
| APA | He, Juan.,Peng, Li-Yan.,Tu, Lin.,Wu, Xing-De.,Dong, Liao-Bing.,...&Zhao, Qin-Shi.(2016).Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum.FITOTERAPIA,109,224-229. |
| MLA | He, Juan,et al."Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissimum".FITOTERAPIA 109(2016):224-229. |
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