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The dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2-dependent and -independent fever while 4-AA only blocks PGE2-dependent fever1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
Authors:  David do C. Malvar;  Fernando A. Aguiar;  Artur de L. L. Vaz;  Débora C. R. Assis;  Miriam C. C. de Melo;  Valquíria A. P. Jabor;  Evanguedes Kalapothakis;  Sérgio H. Ferreira;  Giuliano C. Clososki;  Glória E. P. de Souza
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Dipyrone  Dipyrone Metabolites  Fever  Hypothermia  Lps  Tityus Serrulatus Venom  
Structural and mechanistic basis of penicillin-bindingprotein inhibition by lactivicins 期刊论文
NATURE CHEMICAL BIOLOGY, 3111, 期号: 0, 页码: 1—5
Authors:  Pauline Macheboeuf;  Delphine S Fischer;  Tom Brown Jr;  Astrid Zervosen;  Andre´Luxen;  Bernard Joris;  Andrea Dessen;  Christopher J Schofield
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Increased Catalytic Efficiency following Gene Fusion of Bifunctional MethionineSulfoxide Reductase Enzymes from Shewanella oneidensis 期刊论文
Biochemistry, 3111, 页码: 1—9
Authors:  C.B. Li;  D.M. Zhang;  S. Ge;  D.Y. Hong
Adobe PDF(436Kb)  |  Favorite  |  View/Download:10/1  |  Submit date:2017/07/19
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
Authors:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
View  |  Adobe PDF(500Kb)  |  Favorite  |  View/Download:158/55  |  Submit date:2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
New phloroglucinol derivatives with protein tyrosine phosphatase 1B (PTP1B) inhibitory activities from Syzygium austroyunnanense 期刊论文
FITOTERAPIA, 2018, 卷号: 131, 页码: 141-145
Authors:  Xu, Shao-Hua;  Xu, Wen;  Wang, Li;  Hu, Yi-Kao;  Liu, Jin-Ping;  Zhao, Yan;  Li, Meng-Jia;  Li, Feng;  Huang, Sheng-Xiong;  Zhao, Yong
Favorite  |  View/Download:8/0  |  Submit date:2019/03/18
Syzygium austroyunnanense  Myrtaceae  Phloroglucinol derivatives  Structure elucidation  PTP 1B inhibitory activities  
Metabolomic analysis of cholestatic liver damage in mice 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2018, 卷号: 120, 页码: 253-260
Authors:  Yang, Rui;  Zhao, Qi;  Hu, Dan-Dan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Li, Fei
Favorite  |  View/Download:23/0  |  Submit date:2018/11/12
Cholestatic liver damage  PBC  PSC  Metabolomics  QTOFMS  
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
Authors:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(1313Kb)  |  Favorite  |  View/Download:53/3  |  Submit date:2018/10/07
Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis  
12th全国天然有机化学学术会议摘要集 会议录
Editors:  中国化学会
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Substituting one &ITParis &ITfor another?&IT In vitro&IT cytotoxic and &ITin vivo &ITantitumor activities of &ITParis forrestii&IT, a substitute of &ITParis polyphylla &ITvar. &ITyunnanensis&IT 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 218, 期号: 1, 页码: 45-50
Authors:  Wang, Yue-Hu;  Shi, Min;  Niu, Hong-Mei;  Yang, Jun;  Xia, Meng-Yuan;  Luo, Ji-Feng;  Chen, Ying-Jie;  Zhou, Yi-Ping;  Li, Heng
View  |  Adobe PDF(723Kb)  |  Favorite  |  View/Download:156/11  |  Submit date:2018/05/08
Melanthiaceae  Paris Forrestii  Saponins  Cytotoxicity  Anticancer  
Turnover of Glycerolipid Metabolite Pool and Seed Viability 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 5, 页码: 1417
Authors:  Hu, Xiao-Long;  Yu, Xiao-Mei;  Chen, Hong-Ying;  Li, Wei-Qi
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Hydration-dehydration Cycle  Membrane Lipids  Seed Viability  Phosphatidic Acid (Pa)  Diacylglycerol (Dag)