Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia

doi:10.1039/d0qo01565b

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	Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia
	Shi,Bao-Bao ; Lu,Jing-Song ; Wu,Jing ; Bao,Mei-Fen ; Cai,Xiang-Hai
	2021
Source Publication	ORGANIC CHEMISTRY FRONTIERS
ISSN	2052-4129
Volume	8 Issue:11 Pages:2601-2607
Abstract	A symmetric monoterpenoid indole alkaloid trimer, bousangustine A, is reported for the first time, as well as the dimeric alkaloids bousangustines B and C; these were isolated from the trunks of Bousigonia angustifolia. The structures, which feature a symmetric 6/9/5/6 ring system, were elucidated using comprehensive spectroscopic analysis. Their absolute configurations were determined via X-ray crystal diffraction, as well as computational chemistry. They can be constructed through Friedel-Crafts and free radical reactions, respectively. These compounds exhibited significant cytotoxicity against tumor cells.
Keyword	ERYTHRINA ALKALOIDS
DOI	10.1039/d0qo01565b
WOS ID	WOS:000637371600001
Citation statistics
Document Type	期刊论文
Identifier	http://ir.kib.ac.cn/handle/151853/73777
Collection	中国科学院昆明植物研究所
Affiliation	1.[Shi, Bao-Bao 2.Wu, Jing 3.Bao, Mei-Fen 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 6.Beijing Univ Chinese Med, Dongzhimen Hosp, Beijing 100700, Peoples R China
Recommended Citation GB/T 7714	Shi,Bao-Bao,Lu,Jing-Song,Wu,Jing,et al. Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia[J]. ORGANIC CHEMISTRY FRONTIERS,2021,8(11):2601-2607.
APA	Shi,Bao-Bao,Lu,Jing-Song,Wu,Jing,Bao,Mei-Fen,&Cai,Xiang-Hai.(2021).Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia.ORGANIC CHEMISTRY FRONTIERS,8(11),2601-2607.
MLA	Shi,Bao-Bao,et al."Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia".ORGANIC CHEMISTRY FRONTIERS 8.11(2021):2601-2607.

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