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Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia
Shi,Bao-Bao; Lu,Jing-Song; Wu,Jing; Bao,Mei-Fen; Cai,Xiang-Hai
2021
Source PublicationORGANIC CHEMISTRY FRONTIERS
ISSN2052-4129
Volume8Issue:11Pages:2601-2607
AbstractA symmetric monoterpenoid indole alkaloid trimer, bousangustine A, is reported for the first time, as well as the dimeric alkaloids bousangustines B and C; these were isolated from the trunks of Bousigonia angustifolia. The structures, which feature a symmetric 6/9/5/6 ring system, were elucidated using comprehensive spectroscopic analysis. Their absolute configurations were determined via X-ray crystal diffraction, as well as computational chemistry. They can be constructed through Friedel-Crafts and free radical reactions, respectively. These compounds exhibited significant cytotoxicity against tumor cells.
KeywordERYTHRINA ALKALOIDS
DOI10.1039/d0qo01565b
WOS IDWOS:000637371600001
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Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/73777
Collection中国科学院昆明植物研究所
Affiliation1.[Shi, Bao-Bao
2.Wu, Jing
3.Bao, Mei-Fen
4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
6.Beijing Univ Chinese Med, Dongzhimen Hosp, Beijing 100700, Peoples R China
Recommended Citation
GB/T 7714
Shi,Bao-Bao,Lu,Jing-Song,Wu,Jing,et al. Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia[J]. ORGANIC CHEMISTRY FRONTIERS,2021,8(11):2601-2607.
APA Shi,Bao-Bao,Lu,Jing-Song,Wu,Jing,Bao,Mei-Fen,&Cai,Xiang-Hai.(2021).Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia.ORGANIC CHEMISTRY FRONTIERS,8(11),2601-2607.
MLA Shi,Bao-Bao,et al."Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia".ORGANIC CHEMISTRY FRONTIERS 8.11(2021):2601-2607.
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