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Antimicrobial Peptide Brevivin-1RL1 from Frog Skin Secretion Induces Apoptosis and Necrosis of Tumor Cells 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 7, 页码: 2059
作者:  Ju,Xiaoman;  Fan,Dongmei;  Kong,Lingmei;  Yang,Qihong;  Zhu,Yiying;  Zhang,Shaohua;  Su,Guifeng;  Li,Yan
浏览  |  Adobe PDF(3074Kb)  |  收藏  |  浏览/下载：122/44  |  提交时间：2022/04/02
antimicrobial peptide  Brevivin-1RL1  apoptosis  necrosis  caspase  anticancer  BULLFROG  PHOSPHATIDYLSERINE  MECHANISMS  ANTITUMOR  SURFACE  
USP47 maintains the stemness of colorectal cancer cells and is inhibited by parthenolide 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 卷号: 562, 页码: 21-28
作者:  Zhang,Shaohua;  Ju,Xiaoman;  Yang,Qihong;  Zhu,Yiying;  Fan,Dongmei;  Su,Guifeng;  Kong,Lingmei;  Li,Yan
浏览  |  Adobe PDF(2615Kb)  |  收藏  |  浏览/下载：124/34  |  提交时间：2022/04/02
USP47  Cancer stem cell  Colorectal cancer  Parthenolide  Deubiquitinase  SESQUITERPENE LACTONE PARTHENOLIDE  DEUBIQUITINASES  STABILIZATION  LEUKEMIA  
Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020
作者:  Li, Xue;  Kong, Lingmei;  Yang, Qihong;  Duan, Aizhu;  Ju, Xiaoman;  Cai, Bicheng;  Chen, Lin;  An, Tao;  Li, Yan
浏览  |  Adobe PDF(2381Kb)  |  收藏  |  浏览/下载：118/56  |  提交时间：2021/01/05
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
Adobe PDF(5724Kb)  |  收藏  |  浏览/下载：362/41  |  提交时间：2017/12/18
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
作者:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
Adobe PDF(3138Kb)  |  收藏  |  浏览/下载：770/141  |  提交时间：2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer  
microRNA-375 inhibits colorectal cancer cells proliferation by downregulating JAK2/STAT3 and MAP3K8/ERK signaling pathways 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 10, 页码: 16633-16641
作者:  Wei, Ran;  Yang, Qin;  Han, Bing;  Li, Yan;  Yao, Kun;  Yang, Xiuyu;  Chen, Zexi;  Yang, Shanshan;  Zhou, Jiaqi;  Li, Meizhang;  Yu, Haijing;  Yu, Min;  Cui, Qinghua
Adobe PDF(12068Kb)  |  收藏  |  浏览/下载：405/34  |  提交时间：2017/04/19
Microrna-375  Colorectal Cancer  Jak2/stat3 Pathway  Map3k8/erk Pathway  Atg7  
Pestalotiopsin C, stereochemistry of a new caryophyllene from a fungus of Trichoderma sp and its tautomerization characteristics in solution 期刊论文
TETRAHEDRON, 2015, 卷号: 71, 期号: 21, 页码: 3491-3494
作者:  Yu, He;  Li, Wen-Xin;  Wang, Jing-Chen;  Yang, Qin;  Wang, Hui-Jun;  Zhang, Can-Can;  Ding, Shuang-Shuang;  Li, Yan;  Zhu, Hua-Jie;  Zhu,HJ (reprint author),Hebei Univ,Coll Pharm,Chinese Ctr Chiral,Key Lab Med Chem & Mol Diagnost,Minist Educ,Baoding 071002,Hebei,Peoples R China.;  hjzhu@mail.kib.ac.cn
Adobe PDF(627Kb)  |  收藏  |  浏览/下载：304/159  |  提交时间：2015/07/20
Pestalotiopsin c  Trichoderma Sp  Optical Rotation  Ecd  Transition State  
Cytochalasins from cultures of endophytic fungus Phoma multirostrata EA-12 期刊论文
JOURNAL OF ANTIBIOTICS, 2015, 卷号: 68, 期号: 1, 页码: 23-26
作者:  Chen, Zi-ming;  Chen, He-Ping;  Li, Yan;  Feng, Tao;  Liu, Ji-Kai;  Feng,T (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,134 Lanhei Rd,Kunming 605201,Peoples R China.;  fengtao@mail.kib.ac.cn;  jkliu@mail.kib.ac.cn
Adobe PDF(349Kb)  |  收藏  |  浏览/下载：482/100  |  提交时间：2015/06/29
Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with beta-Catenin/TCF4 Interaction in Colorectal Cancer Cells 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 7, 页码: e68525
作者:  Li, Xingyao;  Pu, Jianxin;  Jiang, Shiyou;  Su, Jia;  Kong, Lingmei;  Mao, Bingyu;  Sun, Handong;  Li, Yan
Adobe PDF(1775Kb)  |  收藏  |  浏览/下载：532/83  |  提交时间：2013/10/16
Beta-catenin  Colon-cancer  Response Element  Activation  Expression  Pathway  Complex  Growth  Apc  Antagonists  
Dual Carbamoylations on the Polyketide and Glycosyl Moiety by Asm21 Result in Extended Ansamitocin Biosynthesis 期刊论文
CHEMISTRY & BIOLOGY, 2011, 卷号: 18, 期号: 12, 页码: 1571-1580
作者:  Li, Yan;  Zhao, Peiji;  Kang, Qianjin;  Ma, Juan;  Bai, Linquan;  Deng, Zixin
Adobe PDF(986Kb)  |  收藏  |  浏览/下载：341/94  |  提交时间：2012/07/25
Antitumor Agent Ansamitocin  Beta-lactam Antibiotics  Actinosynnema-pretiosum  Gene-cluster  Dna Gyrase  Concanamycin-a  Streptomyces  Novobiocin  Carbamoyltransferase  Inhibitors