| Pestalotiopsin C, stereochemistry of a new caryophyllene from a fungus of Trichoderma sp and its tautomerization characteristics in solution | |
Yu, He1; Li, Wen-Xin1; Wang, Jing-Chen1; Yang, Qin1; Wang, Hui-Jun1; Zhang, Can-Can1; Ding, Shuang-Shuang1; Li, Yan2 ; Zhu, Hua-Jie1; Zhu,HJ (reprint author),Hebei Univ,Coll Pharm,Chinese Ctr Chiral,Key Lab Med Chem & Mol Diagnost,Minist Educ,Baoding 071002,Hebei,Peoples R China.; hjzhu@mail.kib.ac.cn
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| 2015-05-27 | |
| 发表期刊 | TETRAHEDRON
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| 卷号 | 71期号:21页码:3491-3494 |
| 摘要 | A new pestalotiopsin C (1) with three known compounds (2-4) are obtained from the fermentation broth of fungus of Trichoderma KK19L1 sp. Pestalotiopsin C (I) has two atropisomers with mole ratio of 1.2/1 in chloroform at room temperature. Its structure was well established by 1D and 2D NMR, and further confirmed by X-ray diffraction. Its absolute configuration (AC) was determined by comparing its experimental electronic circular dichroism (ECD) and optical rotation (OR) value with the calculated ECD and OR data using quantum methods. The bioactivity of compound 1 was tested against five cell-lines HL-60, SMMC-7721, A-549, MCF-7, SW480, respectively. (C) 2015 Elsevier Ltd. All rights reserved. |
| 关键词 | Pestalotiopsin c Trichoderma Sp Optical Rotation Ecd Transition State |
| 学科领域 | Chemistry, Organic |
| DOI | 10.1016/j.tet.2015.03.063 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000355031000041 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/21330 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Zhu,HJ (reprint author),Hebei Univ,Coll Pharm,Chinese Ctr Chiral,Key Lab Med Chem & Mol Diagnost,Minist Educ,Baoding 071002,Hebei,Peoples R China.; hjzhu@mail.kib.ac.cn |
| 作者单位 | 1.Hebei Univ, Coll Pharm, Chinese Ctr Chiral, Key Lab Med Chem & Mol Diagnost,Minist Educ, Baoding 071002, Hebei, Peoples R China 2.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, He,Li, Wen-Xin,Wang, Jing-Chen,et al. Pestalotiopsin C, stereochemistry of a new caryophyllene from a fungus of Trichoderma sp and its tautomerization characteristics in solution[J]. TETRAHEDRON,2015,71(21):3491-3494. |
| APA | Yu, He.,Li, Wen-Xin.,Wang, Jing-Chen.,Yang, Qin.,Wang, Hui-Jun.,...&hjzhu@mail.kib.ac.cn.(2015).Pestalotiopsin C, stereochemistry of a new caryophyllene from a fungus of Trichoderma sp and its tautomerization characteristics in solution.TETRAHEDRON,71(21),3491-3494. |
| MLA | Yu, He,et al."Pestalotiopsin C, stereochemistry of a new caryophyllene from a fungus of Trichoderma sp and its tautomerization characteristics in solution".TETRAHEDRON 71.21(2015):3491-3494. |
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