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Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway 期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
作者:  Yang,Hao-Jie;  Li,Ya-Nan;  Yan,Chen;  Yang,Jue;  Zeng,Yan-Rong;  Yi,Ping;  Li,Yan-Mei;  Hao,Xiao-Jiang;  Yuan,Chun-Mao
浏览  |  Adobe PDF(2804Kb)  |  收藏  |  浏览/下载：65/19  |  提交时间：2022/04/02
Dysoxylum gotadhora  Rocaglaol derivatives  HCT116  Cytotoxic activity  MAPK pathway  FLAVAGLINES  
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
作者:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
浏览  |  Adobe PDF(2105Kb)  |  收藏  |  浏览/下载：89/41  |  提交时间：2022/04/02
Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA  
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 卷号: 17, 期号: 11, 页码: 2703-2717
作者:  Wei,Ruiran;  Zhao,Yueqin;  Wang,Juan;  Yang,Xu;  Li,Shunlin;  Wang,Yinyuan;  Yang,Xingzhi;  Fei,Jimin;  Hao,Xiaojiang;  Zhao,Yuhan;  Gui,Liming;  Ding,Xiao
浏览  |  Adobe PDF(9123Kb)  |  收藏  |  浏览/下载：77/12  |  提交时间：2022/04/02
Ferroptosis  Tagitinin c  Ros  Er Stress  Nrf2-ho-1 Pathway  Endoplasmic-reticulum Stress  Er-stress  Oxidative Stress  Tumor-suppressor  Nrf2  Death  Iron  Differentiation  Mechanisms  Resistance  
Natural product sciences: an integrative approach to the innovations of plant natural products 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2020
作者:  Shen, Yuemao;  Hao, Xiaojiang
浏览  |  Adobe PDF(4992Kb)  |  收藏  |  浏览/下载：94/14  |  提交时间：2021/01/05
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
浏览  |  Adobe PDF(2607Kb)  |  收藏  |  浏览/下载：270/46  |  提交时间：2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Meroterpenoids with Antitumor Activities from Guava (Psidium guajava) 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2017, 卷号: 65, 期号: 24, 页码: 4993-4999
作者:  Qin, Xu-Jie;  Yu, Qian;  Yan, Huan;  Khan, Afsar;  Feng, Mi-Yan;  Li, Pan-Pan;  Hao, Xiao-Jiang;  An, Lin-Kun;  Liu, Hai-Yang
浏览  |  Adobe PDF(3439Kb)  |  收藏  |  浏览/下载：273/82  |  提交时间：2017/07/31
Guava  Meroterpenoids  Cytotoxicity  Dna Topoisomerase i Inhibitors  Antiproliferative Activity  
A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 10, 页码: 1617
作者:  Hong, Ming;  Zhang, Yongsheng;  Li, Sha;  Tan, Hor Yue;  Wang, Ning;  Mu, Shuzhen;  Hao, Xiaojiang;  Feng, Yibin
浏览  |  Adobe PDF(92Kb)  |  收藏  |  浏览/下载：154/63  |  提交时间：2018/05/08
Wuweizi  Network Pharmacology  Hepatoprotective Effect  
A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30 期刊论文
CELL RESEARCH, 2014, 卷号: 24, 期号: 4, 页码: 482-496
作者:  Yue, Wen;  Chen, Ziheng;  Liu, Haiyang;  Yan, Chen;  Chen, Ming;  Feng, Du;  Yan, Chaojun;  Wu, Hao;  Du, Lei;  Wang, Yueying;  Liu, Jinhua;  Huang, Xiaohu;  Xia, Laixin;  Liu, Lei;  Wang, Xiaohui;  Jin, Haijing;  Wang, Jun;  Song, Zhiyin;  Hao, Xiaojiang;  Chen, Quan
浏览  |  Adobe PDF(1659Kb)  |  收藏  |  浏览/下载：596/56  |  提交时间：2014/05/16
Mitochondrial Fusion  Mitofusin1/2  Deubiquitinase Usp30  15-oxospiramilactone  
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
浏览  |  Adobe PDF(2679Kb)  |  收藏  |  浏览/下载：290/57  |  提交时间：2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer  
Antiproliferative Cardiac Glycosides from the Latex of Antiaris toxicaria 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 9, 页码: 1771-1780
作者:  Liu, Qian;  Tang, Jin-Shan;  Hu, Meng-Jie;  Liu, Jie;  Chen, Hai-Feng;  Gao, Hao;  Wang, Guang-Hui;  Li, Shun-Lin;  Hao, Xiao-Jiang;  Zhang, Xiao-Kun;  Yao, Xin-Sheng
浏览  |  Adobe PDF(2429Kb)  |  收藏  |  浏览/下载：198/90  |  提交时间：2015/05/13