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Metabolomics reveals metabolite changes of patients with pulmonary arterial hypertension in China 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2020, 页码: 13
作者:  Chen, Chenyang;  Luo, Fei;  Wu, Panyun;  Huang, Yiyuan;  Das, Avash;  Chen, Shenglan;  Chen, Jingyuan;  Hu, Xinqun;  Li, Fei;  Fang, Zhenfei;  Zhou, Shenhua
收藏  |  浏览/下载：104/0  |  提交时间：2020/03/18
lipid metabolism  metabolomics  pulmonary arterial hypertension  
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：197/41  |  提交时间：2020/03/26
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1740Kb)  |  收藏  |  浏览/下载：197/22  |  提交时间：2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Total synthesis of dryocrassin ABBA and its analogues with potential inhibitory activity against drug-resistant neuraminidases 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 17, 页码: 3846-3852
作者:  Hou, Bo;  Liu, Ze;  Yang, Xiao-Bei;  Zhu, Wen-Fei;  Li, Jin-Yu;  Yang, Liu;  Reng, Fu-Cai;  Lv, Yong-Feng;  Hu, Jiang-Miao;  Liao, Guo-Yang;  Zhou, Jun
浏览  |  Adobe PDF(1817Kb)  |  收藏  |  浏览/下载：156/33  |  提交时间：2019/09/10
Dryocrassin ABBA  Neuraminidase  Total synthesis  Shanghai H7N9  Anhui H7N9  
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3136Kb)  |  收藏  |  浏览/下载：167/56  |  提交时间：2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(3915Kb)  |  收藏  |  浏览/下载：225/40  |  提交时间：2019/07/29
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(1101Kb)  |  收藏  |  浏览/下载：239/104  |  提交时间：2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
New 4,5-seco-20(10 -> 5)-abeo-Abietane Diterpenoids with Anti-Inflammatory Activity from Isodon lophanthoides var. graciliflorus (Benth.) H.Hara 期刊论文
CHEMISTRY & BIODIVERSITY, 2019, 卷号: 16, 期号: 6, 页码: 7
作者:  Chen, Wen-Fei;  Wong, Lai-Lai;  Zhang, Xuan;  Zhou, Feng-Xu;  Xia, Fan;  Tang, Li-Ping;  Li, Xian
Adobe PDF(319Kb)  |  收藏  |  浏览/下载：160/27  |  提交时间：2019/07/29
Isodon lophanthoides  4  5-seco-20(10 -> 5)-abeo-abietane diterpenoid  structure elucidation  anti-inflammatory activity  biological activity  
Characterization of a sesquiterpene cyclase from the glandular trichomes of Leucosceptrum canum for sole production of cedrol in Escherichia coli and Nicotiana benthamiana 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162, 页码: 121-128
作者:  Luo, Fei;  Ling, Yi;  Li, De-Sen;  Tang, Ting;  Liu, Yan-Chun;  Liu, Yan;  Li, Sheng-Hong
Adobe PDF(2851Kb)  |  收藏  |  浏览/下载：205/36  |  提交时间：2019/07/29
Leucosceptrum canum  Lamiaceae  Cedrol  Sesquiterpene cylase  Cedrol synthase  Heterologous production  Synthetic biology  
Metabolic Activation of Myristicin and Its Role in Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 15, 页码: 4328-4336
作者:  Zhu, Xu;  Wang, Yi-Kun;  Yang, Xiao-Nan;  Xiao, Xue-Rong;  Zhang, Ting;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Li, Fei
Adobe PDF(4316Kb)  |  收藏  |  浏览/下载：221/40  |  提交时间：2019/05/24
myristicin  1 '-hydroxymyristicin  metabolic activation  metabolomics