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Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(5724Kb)  |  收藏  |  浏览/下载:383/42  |  提交时间:2017/12/18
New neo-clerodane diterpenoids with neurotrophic activity from the aerial parts of Salvia tiliifolia 期刊论文
FITOTERAPIA, 2017, 卷号: 123, 页码: 44-50
作者:  Fan, Min;  Bao, Ying;  Zhang, Zhi-Jun;  Zhang, Hong-Bin;  Zhao, Qin-Shi
浏览  |  Adobe PDF(515Kb)  |  收藏  |  浏览/下载:163/62  |  提交时间:2018/05/08
Salvia Tiliifolia  Neo-clerodane Diterpenoids  Neurotrophic Activities  Cytotoxicity  
Vibsanin B Preferentially Targets HSP90b, Inhibits Interstitial Leukocyte Migration, and Ameliorates Experimental Autoimmune Encephalomyelitis 期刊论文
JOURNAL OF IMMUNOLOGY, 2015, 卷号: 194, 期号: 9, 页码: 4489-4497
作者:  Ye, Bai-Xin;  Deng, Xu;  Shao, Li-Dong;  Lu, Ying;  Xiao, Run;  Liu, Yi-Jie;  Jin, Yi;  Xie, Yin-Yin;  Zhao, Yan;  Luo, Liu-Fei;  Ma, Shun;  Gao, Ming;  Zhang, Lian-Ru;  He, Juan;  Zhang, Wei-Na;  Chen, Yi;  Xia, Cheng-Feng;  Deng, Min;  Liu, Ting-Xi;  Zhao, Qin-Shi;  Chen, Sai-Juan;  Chen, Zhu;  Chen,Z (reprint author),Shanghai Jiao Tong Univ,RuiJin Hosp,Sch Med,197 Rui Jin Rd 2,Shanghai 200025,Peoples R China.;  qinshizhao@mail.kib.ac.cn;  sjchen@stn.sh.cn;  zchen@stn.sh.cn
浏览  |  Adobe PDF(1516Kb)  |  收藏  |  浏览/下载:279/44  |  提交时间:2015/07/20
Mechanisms of the dilator action of the Erigerontis Herba on rat aorta 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2014, 卷号: 155, 期号: 3, 页码: 1561-1567
作者:  Koon, Chi-Man;  Fong, Subiyanto;  Wat, Elaine;  Wang, Yan-Ping;  Cheung, David Wing-Shing;  Lau, Clara Bik-San;  Leung, Ping-Chung;  Sun, Han-Dong;  Zhao, Qin-Shi;  Fung, Kwok-Pui;  Fung,KP (reprint author),Chinese Univ Hong Kong,Sch Biomed Sci,Room 509A,Shatin,Hong Kong,Peoples R China.;  kpfung@cuhk.edu.hk
Adobe PDF(493Kb)  |  收藏  |  浏览/下载:202/57  |  提交时间:2014/11/25
Erigerontis Herba  Vasodilation  Aorta  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
Adobe PDF(1971Kb)  |  收藏  |  浏览/下载:682/104  |  提交时间:2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Cheliensisin A Inhibits EGF-Induced Cell Transformation with Stabilization of p53 Protein Via a Hydrogen Peroxide/Chk1-Dependent Axis 期刊论文
CANCER PREVENTION RESEARCH, 2013, 卷号: 6, 期号: 9, 页码: 949-958
作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Deng, Xu;  Li, Jingxia;  Yu, Yonghui;  Zhang, Dongyun;  Li, Fei;  Zhang, Min;  Zhao, Qinshi;  Huang, Chuanshu
浏览  |  Adobe PDF(1677Kb)  |  收藏  |  浏览/下载:2679/237  |  提交时间:2013/10/16
Dna-damage  Cancer Chemoprevention  Induced Phosphorylation  Activation  Apoptosis  Expression  Induction  Hyperoxia  Therapy  Roles  
Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor gamma synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells 期刊论文
CANCER LETTERS, 2009, 卷号: 275, 期号: 2, 页码: 247-255
作者:  Sun, Wei-Hao;  Chen, Guo-Sheng;  Ou, Xi-Long;  Yang, Ye;  Luo, Cheng;  Zhang, Yuan;  Shao, Yun;  Xu, Hai-Chen;  Xiao, Bin;  Xue, Yi-Ping;  Zhou, Su-Ming;  Zhao, Qin-Shi;  Ding, Guo-Xian
Adobe PDF(635Kb)  |  收藏  |  浏览/下载:1266/368  |  提交时间:2011/12/19
Pancreatic Cancer  Cyclooxygenase-2  Peroxisome Proliferators-activated Receptor  Gamma  Proliferation  Apoptosis  
Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro 期刊论文
CANCER LETTERS, 2008, 卷号: 263, 期号: 2, 页码: 302-311
作者:  Sun, Wei-Hao;  Zhu, Feng;  Chen, Guo-Sheng;  Su, Han;  Luo, Cheng;  Zhao, Qin-Shi;  Zhang, Yuan;  Shao, Yun;  Sun, Jian;  Zhou, Su-Ming;  Ding, Guo-Xian;  Cheng, Yun-Lin
Adobe PDF(809Kb)  |  收藏  |  浏览/下载:349/103  |  提交时间:2011/11/24
Cholecystokinin-2 Receptor  Cyclooxygenase-2  Mkn-45 Cell  Proliferation  Apoptosis  
The functional roles of lipid rafts in T-Cell activation, immune diseases and HIV infection and prevention 期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2008, 卷号: 5, 期号: 1, 页码: 1-7
作者:  Luo, Cheng;  Wang, Kou;  Liu, Dequan;  Li, Yan;  Zhao, Qinshi
Adobe PDF(909Kb)  |  收藏  |  浏览/下载:326/117  |  提交时间:2011/11/24
Lipid Raft  Liquid Ordered Phase  Liquid Crystal Phase  Cholesterol  Virus Assembly  
Michael reaction acceptor molecules in chemical biology 期刊论文
PROGRESS IN CHEMISTRY, 2007, 卷号: 19, 期号: 12, 页码: 1972-1976
作者:  Zhao Qinshi;  Cong Yuwen
Adobe PDF(354Kb)  |  收藏  |  浏览/下载:313/123  |  提交时间:2011/12/19
Michael Reaction Acceptors  Chemical Biology  Molecule Probes