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Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
浏览  |  Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：275/63  |  提交时间：2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells 期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 18, 页码: 3371-3386
作者:  Zhou, Hongyu;  Yu, Chunlei;  Kong, Lingmei;  Xu, Xiaoliang;  Yan, Juming;  Li, Yingchao;  An, Tao;  Gong, Liang;  Gong, Yaxiao;  Zhu, Huifang;  Zhang, Hongbin;  Yang, Xiaodong;  Li, Yan
浏览  |  Adobe PDF(5225Kb)  |  收藏  |  浏览/下载：260/33  |  提交时间：2019/06/24
Synthesis and cytotoxic activity of novel tetrahydrobenzodifuran-imidazolium salt derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 8, 页码: 1808-1814
作者:  Zhang, Chao-Bo;  Liu, Yang;  Liu, Zheng-Fen;  Duan, Sheng-Zu;  Li, Min-Yan;  Chen, Wen;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(1192Kb)  |  收藏  |  浏览/下载：639/109  |  提交时间：2017/06/30
Tetrahydrobenzodifurans  Imidazolium Salts  Cytotoxic Activity  Cell Cycle  Apoptosis  
Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 116, 页码: 39-50
作者:  Zhou, Hongyu;  Shang, Chaowei;  Wang, Min;  Shen, Tao;  Kong, Lingmei;  Yu, Chunlei;  Ye, Zhennan;  Luo, Yan;  Liu, Lei;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(3794Kb)  |  收藏  |  浏览/下载：188/40  |  提交时间：2017/01/05
Ciclopirox  Mtor  Ampk  Tsc2  Raptor  
Synthesis and antitumor activity of novel N-substituted carbazole imidazolium salt derivatives 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Liu, Lan-Xiang;  Wang, Xue-Quan;  Zhou, Bei;  Yang, Li-Juan;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(1438Kb)  |  收藏  |  浏览/下载：1581/808  |  提交时间：2016/01/19
Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 20, 页码: 10140-10150
作者:  Zhou, Hongyu;  Shen, Tao;  Shang, Chaowei;  Luo, Yan;  Liu, Lei;  Yan, Juming;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(2703Kb)  |  收藏  |  浏览/下载：226/50  |  提交时间：2015/06/17
Ciclopirox  Autophagy  Rhabdomyosarcoma  Reactive Oxygen Species  Jnk  
Bioactive ent-Kaurane Diterpenoids from Isodon rosthornii 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 7, 页码: 1267-1277
作者:  Zhan, Rui;  Li, Xiao-Nian;  Du, Xue;  Wang, Wei-Guang;  Dong, Ke;  Su, Jia;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
浏览  |  Adobe PDF(448Kb)  |  收藏  |  浏览/下载：491/238  |  提交时间：2013/10/16
Lasiocarpus Hayata Kudo  Nf-kappa-b  Leukemic-cells  Terpenoids  Rubescens  Differentiation  Cytotoxicity  Constituents  Pharicin  
Drug-mediated inhibition of Fli-1 for the treatment of leukemia 期刊论文
BLOOD CANCER JOURNAL, 2012, 卷号: 2, 页码: e54
作者:  Li, Y-J;  Zhao, X.;  Vecchiarelli-Federico, L. M.;  Li, Y.;  Datti, A.;  Cheng, Y.;  Ben-David, Y.
Adobe PDF(618Kb)  |  收藏  |  浏览/下载：253/53  |  提交时间：2012/06/07
Erythroleukemia  Fli-1  Drug Inhibition  
Development of novel conformation-constrained cytotoxic derivatives of cheliensisin A by embedment of small heterocycles 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 9, 页码: 4238-4244
作者:  Deng, Xu;  Su, Jia;  Zhao, Yu;  Peng, Li-Yan;  Li, Yan;  Yao, Zhu-Jun;  Zhao, Qin-Shi
Adobe PDF(450Kb)  |  收藏  |  浏览/下载：401/100  |  提交时间：2012/03/16
Cheliensisin a  Derivative  Structure-activity Relationship  Cytotoxicity  Anticancer