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Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway 期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
作者:  Yang,Hao-Jie;  Li,Ya-Nan;  Yan,Chen;  Yang,Jue;  Zeng,Yan-Rong;  Yi,Ping;  Li,Yan-Mei;  Hao,Xiao-Jiang;  Yuan,Chun-Mao
浏览  |  Adobe PDF(2804Kb)  |  收藏  |  浏览/下载:91/25  |  提交时间:2022/04/02
Dysoxylum gotadhora  Rocaglaol derivatives  HCT116  Cytotoxic activity  MAPK pathway  FLAVAGLINES  
Sesquiterpene lactones from Carpesium abrotanoides L. and their activity in inducing protective autophagy 期刊论文
NATURAL PRODUCT RESEARCH, 2021
作者:  Yang,Bao-Jia;  Wang,Juan;  Zeng,Zheng-Quan;  Yang,Xu;  Huang,Ai-Ying;  Hao,Xiao-Jiang;  Ding,Xiao;  Li,Shun-Lin
收藏  |  浏览/下载:73/0  |  提交时间:2022/04/02
Carpesium abrotanoides L  sesquiterpene lactone  autophagy  lysosomal biogenesis  cytotoxic activity  
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 卷号: 17, 期号: 11, 页码: 2703-2717
作者:  Wei,Ruiran;  Zhao,Yueqin;  Wang,Juan;  Yang,Xu;  Li,Shunlin;  Wang,Yinyuan;  Yang,Xingzhi;  Fei,Jimin;  Hao,Xiaojiang;  Zhao,Yuhan;  Gui,Liming;  Ding,Xiao
浏览  |  Adobe PDF(9123Kb)  |  收藏  |  浏览/下载:103/15  |  提交时间:2022/04/02
Ferroptosis  Tagitinin c  Ros  Er Stress  Nrf2-ho-1 Pathway  Endoplasmic-reticulum Stress  Er-stress  Oxidative Stress  Tumor-suppressor  Nrf2  Death  Iron  Differentiation  Mechanisms  Resistance  
Phenolic derivatives from Garcinia multiflora Champion ex Bentham and their chemotaxonomic significance 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2020
作者:  Yang, Haojie;  Tian, Dongsong;  Zeng, Yanrong;  Huang, Liejun;  Gu, Wei;  Hao, Xiaojiang;  Yuan, Chunmao
浏览  |  Adobe PDF(569Kb)  |  收藏  |  浏览/下载:107/30  |  提交时间:2021/01/05
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
作者:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li;  Fu, Yan-Hui;  Morris-Natschke, Susan L.;  Hamel, Ernest;  Lee, Kuo-Hsiung;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3129Kb)  |  收藏  |  浏览/下载:238/26  |  提交时间:2019/07/29
aspidosperma-type  monoterpenoid indole alkaloids  antiproliferative activity  tubulin inhibitor  Bousigonia mekongensis  
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
作者:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
浏览  |  Adobe PDF(2055Kb)  |  收藏  |  浏览/下载:282/39  |  提交时间:2019/04/15
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
浏览  |  Adobe PDF(2607Kb)  |  收藏  |  浏览/下载:298/50  |  提交时间:2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Tabercorymines A and B, Two Vobasinyl-Ibogan-Type Bisindole Alkaloids from Tabernaemontana corymbosa 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 18, 页码: 4964-4967
作者:  Yuan, Yu-Xi;  Zhang, Yu;  Guo, Ling-Li;  Wang, Yue-Hu;  Goto, Masuo;  Morris-Natschke, Susan L.;  Lee, Kuo-Hsiung;  Hao, Xiao-Jiang
Adobe PDF(915Kb)  |  收藏  |  浏览/下载:367/111  |  提交时间:2017/10/23
Indole Alkaloids  
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
作者:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
Adobe PDF(3775Kb)  |  收藏  |  浏览/下载:156/38  |  提交时间:2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling  
Garmultins A-G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 22, 页码: 5904-5907
作者:  Tian, Dong Song;  Yi, Ping;  Xia, Lei;  Xiao, Xin;  Fan, Yi Min;  Gu, Wei;  Huang, Lie Jun;  Ben-David, Yaacov;  Di, Ying Tong;  Yuan, Chun Mao;  Hao, Xiao Jiang
Adobe PDF(1168Kb)  |  收藏  |  浏览/下载:366/73  |  提交时间:2017/01/05