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Efficient synthesis of new phenanthridine Wnt/b-catenin signaling pathway agonists 期刊论文
European Journal of Medicinal Chemistry, 2018, 卷号: 157, 页码: 1491-1499
作者:  Duozhi Chen;  Heng Zhang;  Chenxu Jing;  Xiaoli He;  Bijuan Yang;  Jieyun Cai;  Yunfu Zhou;  Xiaoming Song;  Lin Li;  Xiaojiang Hao
浏览  |  Adobe PDF(1966Kb)  |  收藏  |  浏览/下载：222/86  |  提交时间：2019/03/27
A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 10, 页码: 1617
作者:  Hong, Ming;  Zhang, Yongsheng;  Li, Sha;  Tan, Hor Yue;  Wang, Ning;  Mu, Shuzhen;  Hao, Xiaojiang;  Feng, Yibin
浏览  |  Adobe PDF(92Kb)  |  收藏  |  浏览/下载：179/72  |  提交时间：2018/05/08
Wuweizi  Network Pharmacology  Hepatoprotective Effect  
16-nor Limonoids from Harrisonia perforata as promising selective 11 beta-HSD1 inhibitors 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 1
作者:  Xiao-HuiYan;  Yi, Ping;  Cao, Pei;  Yang, Shi-Ying;  Fang, Xin;  Zhang, Yu;  Wu, Bin;  Leng, Ying;  Di, Ying-Tong;  Lv, Yang;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1151Kb)  |  收藏  |  浏览/下载：354/57  |  提交时间：2017/01/05
Protein kinase C controls lysosome biogenesis independently of mTORC1 期刊论文
NATURE CELL BIOLOGY, 2016, 卷号: 18, 期号: 10, 页码: 1065-1077
作者:  Li, Yang;  Xu, Meng;  Ding, Xiao;  Yan, Chen;  Song, Zhiqin;  Chen, Lianwan;  Huang, Xiahe;  Wang, Xin;  Jian, Youli;  Tang, Guihua;  Tang, Changyong;  Di, Yingtong;  Mu, Shuzhen;  Liu, Xuezhao;  Liu, Kai;  Li, Ting;  Wang, Yingchun;  Miao, Long;  Guo, Weixiang;  Hao, Xiaojiang;  Yang, Chonglin
浏览  |  Adobe PDF(4637Kb)  |  收藏  |  浏览/下载：571/152  |  提交时间：2016/12/21
Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 180-188
作者:  Chen, Duo-Zhi;  Jing, Chen-Xu;  Cai, Jie-Yun;  Wu, Ji-Bo;  Wang, Sheng;  Yin, Jun -Lin;  Li, Xiao-Nian;  Li, Lin;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3043Kb)  |  收藏  |  浏览/下载：322/76  |  提交时间：2016/06/27
Unprecedented Quassinoids with Promising Biological Activity from Harrisonia perforata 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 卷号: 54, 期号: 19, 页码: 5592-5595
作者:  Fang, Xin;  Di, Ying Tong;  Zhang, Yu;  Xu, Zhi Ping;  Lu, Yang;  Chen, Qian Qian;  Zheng, Qi Tai;  Hao, Xiao Jiang;  Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  haoxj@mail.kib.ac.cn
浏览  |  Adobe PDF(931Kb)  |  收藏  |  浏览/下载：314/108  |  提交时间：2015/07/20
Biosynthetic Pathways  Insecticidal Activity  Natural Products  Nicotinic Acetylcholine Receptors  Structure Elucidation  
Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction 期刊论文
NATURE CHEMICAL BIOLOGY, 2013, 卷号: 9, 期号: 9, 页码: 579-U82
作者:  Wang, Sheng;  Yin, Junlin;  Chen, Duozhi;  Nie, Fen;  Song, Xiaomin;  Fei, Cong;  Miao, Haofei;  Jing, Changbin;  Ma, Wenjing;  Wang, Lei;  Xie, Sichun;  Li, Chen;  Zeng, Rong;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(1157Kb)  |  收藏  |  浏览/下载：631/127  |  提交时间：2013/10/16
Glycogen-synthase Kinase-3  Beta-catenin  Negative Regulator  Dix Domain  Stem-cells  In-vivo  Axin  Activation  Pathway  Phosphorylation  
Shizukaol D Isolated from Chloranthus japonicas Inhibits AMPK-Dependent Lipid Content in Hepatic Cells by Inducing Mitochondrial Dysfunction 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e73527
作者:  Hu, Rongkuan;  Yan, Huan;  Hao, Xiaojiang;  Liu, Haiyang;  Wu, Jiarui
浏览  |  Adobe PDF(1041Kb)  |  收藏  |  浏览/下载：565/78  |  提交时间：2013/10/16
Activated Protein-kinase  Fatty-acid Oxidation  Respiratory Complex-i  Insulin-resistance  Malonyl-coa  Signaling Pathways  Glucose-uptake  L6 Myotubes  Hepg2 Cells  Metformin  
Resin Glycoside Constituents of Ipomoea pes-caprae (Beach Morning Glory) 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2008, 卷号: 71, 期号: 12, 页码: 1998-2003
作者:  Tao, Hongwen;  Hao, Xiaojiang;  Liu, Jinggen;  Ding, Jian;  Fang, Yuchun;  Gu, Qianqun;  Zhu, Weiming
Adobe PDF(745Kb)  |  收藏  |  浏览/下载：896/206  |  提交时间：2011/11/24
L. R-br  I-vii  Extract  Pentasaccharides  Inhibition  Assay  
Effects of spiramine T on antioxidant enzymatic activities and nitric oxide production in cerebral ischemia-reperfusion gerbils 期刊论文
BRAIN RESEARCH, 2002, 卷号: 944, 期号: 1-2, 页码: 205-209
作者:  Li, L;  Shen, YM;  Yang, XS;  Wu, WL;  Wang, BG;  Chen, ZH;  Hao, XJ
Adobe PDF(294Kb)  |  收藏  |  浏览/下载：313/106  |  提交时间：2012/03/21
Spiraea Japonica Var. Acuta  Rosaceae  Spiramine t  Cerebral Ischemia-reperfusion  Antioxidant Enzyme  Nitric Oxide Synthase