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Small-Molecule Drugs in Immunotherapy 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359
作者:  Hao,Xuanrun;  Chen,Zhongliang;  Li,Haining;  Wei,Minqin;  Zuo,Zhili;  Su,Qing
浏览  |  Adobe PDF(29350Kb)  |  收藏  |  浏览/下载：14/4  |  提交时间：2024/07/25
Cancer immunotherapy  inhibitors  Pd-1/Pd-L1 inhibitor  IDO inhibitor  STING agonists  ROR gamma t agonists  TGF  beta inhibitors  INDOLEAMINE 2,3-DIOXYGENASE  SIGNALING INHIBITOR  DENDRITIC CELLS  GROWTH  TUMOR  PATHWAY  PEMBROLIZUMAB  RECEPTORS  DISCOVERY  VADIMEZAN  
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
浏览  |  Adobe PDF(7197Kb)  |  收藏  |  浏览/下载：13/3  |  提交时间：2024/07/30
PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE  
Polysaccharide-Peptide from Trametes versicolor: The Potential Medicine for Colorectal Cancer Treatment 期刊论文
BIOMEDICINES, 2022, 卷号: 10, 期号: 11, 页码: 2841
作者:  He, Zhicheng;  Lin, Jian;  He, Yingying;  Liu, Shubai
浏览  |  Adobe PDF(8865Kb)  |  收藏  |  浏览/下载：94/4  |  提交时间：2024/04/30
Trametes versicolor  polysaccharide peptide  colorectal cancer  traditional medicine  PROTEIN-BOUND POLYSACCHARIDE  QUEL PS-K  CORIOLUS-VERSICOLOR  IN-VITRO  ANTICANCER ACTIVITY  SIGNALING PATHWAY  ANTITUMOR  CELLS  MUSHROOM  COMBINATION  
Mechanisms of Abscisic Acid-Mediated Drought Stress Responses in Plants 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 3, 页码: 1084
作者:  Aslam, Mehtab Muhammad;  Waseem, Muhammad;  Jakada, Bello Hassan;  Okal, Eyalira Jacob;  Lei, Zuliang;  Saqib, Hafiz Sohaib Ahmad;  Yuan, Wei;  Xu, Weifeng;  Zhang, Qian
浏览  |  Adobe PDF(1814Kb)  |  收藏  |  浏览/下载：57/14  |  提交时间：2024/04/30
ABA  drought  metabolites  signaling  crop breeding  E3 UBIQUITIN LIGASE  ACTIVATED PROTEIN-KINASES  TRANSCRIPTION FACTOR  POSITIVE REGULATOR  WATER-STRESS  ROOT-GROWTH  GENE-EXPRESSION  ARABIDOPSIS-THALIANA  SIGNAL-TRANSDUCTION  AUXIN TRANSPORT  
Polysaccharide Peptide Induced Colorectal Cancer Cells Apoptosis by Down-Regulating EGFR and PD-L1 Expression 期刊论文
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2022, 卷号: 21, 期号: 1, 页码: e123909
作者:  Lin Jian;  He Zhicheng;  Liu Shubai
浏览  |  Adobe PDF(3879Kb)  |  收藏  |  浏览/下载：11/2  |  提交时间：2024/08/21
Colorectal Cancer  Trametes Versicolor  EGFR  PD-L1  Polysaccharide Peptide  CORIOLUS-VERSICOLOR  SIGNALING PATHWAY  COLON-CANCER  T-CELLS  STATISTICS  THERAPY  
The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 874474
作者:  Arunachalam, Karuppusamy;  Sreeja, Puthanpura Sasidharan;  Yang, Xuefei
浏览  |  Adobe PDF(2493Kb)  |  收藏  |  浏览/下载：12/5  |  提交时间：2024/08/21
reactive oxygen species  oxidative stress  antioxidant  diabetes mellitus  mushroom polysaccharides  AGARICUS-BLAZEI MURILL  GANODERMA-LUCIDUM POLYSACCHARIDES  ACTIVATED SIGNALING PATHWAYS  TYPE-2 DIABETES-MELLITUS  PROTEIN-KINASE-C  MT-ALPHA-GLUCAN  MEDICINAL MUSHROOM  SUBMERGED-CULTURE  PHELLINUS-LINTEUS  STRUCTURAL-CHARACTERIZATION  
Current Advances in Mechanisms and Treatment of Dry Eye Disease: Toward Anti-inflammatory and Immunomodulatory Therapy and Traditional Chinese Medicine 期刊论文
FRONTIERS IN MEDICINE, 2022, 卷号: 8, 页码: 815075
作者:  Ling, Jiawei;  Chan, Ben Chung-Lap;  Tsang, Miranda Sin-Man;  Gao, Xun;  Leung, Ping Chung;  Lam, Christopher Wai-Kei;  Hu, Jiang-Miao;  Wong, Chun Kwok
浏览  |  Adobe PDF(786Kb)  |  收藏  |  浏览/下载：10/2  |  提交时间：2024/08/21
inflammation  signaling pathways  immunomodulatory therapy  traditional Chinese medicine  dry eye disease  CHRONIC INFLAMMATORY LESIONS  MEIBOMIAN GLAND DYSFUNCTION  OCULAR-SURFACE  OPHTHALMIC SOLUTION  TEAR FILM  SJOGRENS-SYNDROME  ORAL DOXYCYCLINE  MATRIX METALLOPROTEINASES  TOPICAL CORTICOSTEROIDS  CATARACT-SURGERY  
Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
作者:  Li,Xu-xia;  Zhang,Peng;  Yang,Yang;  Wang,Jing-jing;  Zheng,Yan-jun;  Tan,Ji-liang;  Liu,Shen-yan;  Yan,Yong-ming;  Zhang,You-yi;  Cheng,Yong-xian;  Yang,Huang-tian
浏览  |  Adobe PDF(4052Kb)  |  收藏  |  浏览/下载：91/1  |  提交时间：2022/04/02
cardiac hypertrophy  pyrazine derivative  QF84139  phenylephrine  transverse aortic constriction  AMPK signaling pathway  PROTEIN-KINASE  MAMMALIAN TARGET  OVERLOAD  METFORMIN  MACROPHAGES  MECHANISMS  MEDICINE  ALPHA  CELLS  MODEL  
Transcriptomic and Phytochemical Analyses Reveal Root-Mediated Resource-Based Defense Response to Leaf Herbivory by Ectropis oblique in Tea Plant (Camellia sinensis) 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 19, 页码: 5465-5476
作者:  Yang, Hua;  Wang, Yanan;  Li, Longbao;  Li, Fangdong;  He, Yaxian;  Wu, Jianqiang;  Wei, Chaoling
浏览  |  Adobe PDF(5181Kb)  |  收藏  |  浏览/下载：235/12  |  提交时间：2019/07/29
Camellia sinensis  Ectropis oblique  leaf herbivory  systemic root response  carbon reallocation  phytohormone signaling  
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
浏览  |  Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：206/40  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer