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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载:193/0  |  提交时间:2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
作者:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
浏览  |  Adobe PDF(1542Kb)  |  收藏  |  浏览/下载:299/77  |  提交时间:2020/03/18
delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
Rapid discovery and functional characterization of diterpene synthases from basidiomycete fungi by genome mining 期刊论文
FUNGAL GENETICS AND BIOLOGY, 2019, 卷号: 128, 页码: 36-42
作者:  Li, Xin-Lin;  Xu, Yu-Xing;  Li, Yuan;  Zhang, Rui;  Hu, Tian-Yuan;  Su, Ping;  Zhou, Man;  Tang, Ting;  Zeng, Ying;  Yang, Yan-Long;  Gao, Wei
浏览  |  Adobe PDF(1544Kb)  |  收藏  |  浏览/下载:257/44  |  提交时间:2019/07/29
Basidiomycete  Ditepene synthase  Genome mining  Cembrane diterpene  (-)-cyatha-3,12-diene  Ent-kauran-16 alpha-ol  
Non-volatile natural products in plant glandular trichomes: chemistry, biological activities and biosynthesis 期刊论文
NATURAL PRODUCT REPORTS, 2019, 卷号: 36, 期号: 4, 页码: 626-665
作者:  Liu, Yan;  Jing, Shu-Xi;  Luo, Shi-Hong;  Li, Sheng-Hong
浏览  |  Adobe PDF(5702Kb)  |  收藏  |  浏览/下载:236/38  |  提交时间:2019/05/24
Glycoside Hydrolase Family 39 beta-Xylosidases Exhibit beta-1,2-Xylosidase Activity for Transformation of Notoginsenosides: A New EC Subsubclass 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 11, 页码: 3220-3228
作者:  Zhang, Rui;  Li, Na;  Xu, Shujing;  Han, Xiaowei;  Li, Chunyan;  Wei, Xin;  Liu, Yu;  Tu, Tao;  Tang, Xianghua;  Zhou, Junpei;  Huang, Zunxi
浏览  |  Adobe PDF(6317Kb)  |  收藏  |  浏览/下载:167/18  |  提交时间:2019/07/29
beta-xylosidase  beta-1,2-glycosidic bond  enzyme commission  notoginsenosides  glycoside hydrolase family 39  
Diterpenoid compounds from Wedelia trilobata induce resistance to Tomato spotted wilt virus via the JA signal pathway in tobacco plants 期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 12
作者:  Zhao, Lihua;  Hu, Zhonghui;  Li, Shunlin;  Zhou, Xueping;  Li, Jing;  Su, Xiaoxia;  Zhang, Lizhen;  Zhang, Zhongkai;  Dong, Jiahong
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Diterpene synthases facilitating production of the kaurane skeleton of eriocalyxin B in the medicinal plant Isodon eriocalyx 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 158, 页码: 96-102
作者:  Du, Gang;  Gong, Hai-Yan;  Feng, Ke-Na;  Chen, Qian-Qian;  Yang, Yan-Long;  Fu, Xiao-Li;  Lu, Shan;  Zeng, Ying
浏览  |  Adobe PDF(1880Kb)  |  收藏  |  浏览/下载:239/49  |  提交时间:2019/03/18
Isodon eriocalyx  Lamiaceae  Biosynthesis  Diterpenoids  Copalyl diphosphate synthase  Kaurene synthase  IeCPS3  IeKS1  
Plastid phylogenomics resolves infrafamilial relationships of the Styracaceae and sheds light on the backbone relationships of the Ericales 期刊论文
MOLECULAR PHYLOGENETICS AND EVOLUTION, 2018, 卷号: 121, 页码: 198-211
作者:  Yan, Minghui;  Fritsch, Peter W.;  Moore, Michael J.;  Feng, Tao;  Meng, Aiping;  Yang, Jing;  Deng, Tao;  Zhao, Congxiao;  Yao, Xiaohong;  Sun, Hang;  Wang, Hengchang
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Styracaceae  Ericales  Plastome Phylogenomics  Inversion  Gene Loss  
Novel Sodium Channel Inhibitor From Leeches 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 186
作者:  Wang, Gan;  Long, Chengbo;  Liu, Weihui;  Xu, Cheng;  Zhang, Min;  Li, Qiong;  Lu, Qiumin;  Meng, Ping;  Li, Dongsheng;  Rong, Mingqiang;  Sun, Zhaohui;  Luo, Xiaodong;  Lai, Ren
浏览  |  Adobe PDF(1661Kb)  |  收藏  |  浏览/下载:255/47  |  提交时间:2018/05/08
Leech Therapy  Blood-sucking  Sodium Channel  Pain  Analgesia  
Potential role of CYP1B1 in the development and treatment of metabolic diseases 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2017, 卷号: 178, 页码: 18-30
作者:  Li, Fei;  Zhu, Weifeng;  Gonzalez, Frank J.
浏览  |  Adobe PDF(2083Kb)  |  收藏  |  浏览/下载:188/62  |  提交时间:2017/11/20
Cyp1b1  Metabolic Diseases  Metabolic Pathways  Metabolomics