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New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
作者:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
浏览  |  Adobe PDF(5266Kb)  |  收藏  |  浏览/下载：30/9  |  提交时间：2024/05/09
Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE  
Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1088
作者:  Yan,Ying;  Zhou,Qi;  Ran,Xiaoqian;  Lu,Qingyun;  Zhang,Cuishan;  Peng,Mingyou;  Tang,Lei;  Luo,Rongcan;  Di,Yingtong;  Hao,Xiaojiang
浏览  |  Adobe PDF(11343Kb)  |  收藏  |  浏览/下载：28/6  |  提交时间：2024/05/09
euphjatrophane  Euphorbia peplus  jatrophane diterpenoid  autophagy  Tau pathology  UBIQUITIN-PROTEASOME SYSTEM  MULTIDRUG-RESISTANCE  BIOLOGICAL-ACTIVITY  ALZHEIMERS-DISEASE  MODULATORS  CELLS  
Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 7, 页码: 1541-1545
作者:  Chen,Yan-Ni;  Ding,Xiao;  Li,Dong-Mei;  Sun,Mao;  Yang,Lei;  Zhang,Yu;  Di,Ying-Tong;  Fang,Xin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(1835Kb)  |  收藏  |  浏览/下载：92/19  |  提交时间：2022/04/02
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2579Kb)  |  收藏  |  浏览/下载：153/50  |  提交时间：2023/09/08
Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 3, 页码: 357-364
作者:  Chen,Yan-Ni;  Ding,Xiao;  Li,Dong-Mei;  Lu,Qing-Yun;  Liu,Shuai;  Li,Ying-Yao;  Di,Ying-Tong;  Fang,Xin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(1584Kb)  |  收藏  |  浏览/下载：124/26  |  提交时间：2022/04/02
Voacafrines A-N, aspidosperma-type monoterpenoid indole alkaloids from Voacanga africana with AChE inhibitory activity 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 181, 页码: 112566
作者:  Zhao,Qian;  Zhu,Wen-Tao;  Ding,Xiao;  Huo,Zong-Qing;  Donkor,Paul O.;  Adelakun,Tiwalade A.;  Hao,Xiao-Jiang;  Zhang,Yu
浏览  |  Adobe PDF(3237Kb)  |  收藏  |  浏览/下载：134/25  |  提交时间：2022/04/02
Voacanga africana stapf  Apocynaceae  Monoterpenoid indole alkaloids  Voacafrines A-N  AChE inhibitory activity  
Sesquiterpene lactones from Carpesium abrotanoides L. and their activity in inducing protective autophagy 期刊论文
NATURAL PRODUCT RESEARCH, 2021
作者:  Yang,Bao-Jia;  Wang,Juan;  Zeng,Zheng-Quan;  Yang,Xu;  Huang,Ai-Ying;  Hao,Xiao-Jiang;  Ding,Xiao;  Li,Shun-Lin
收藏  |  浏览/下载：73/0  |  提交时间：2022/04/02
Carpesium abrotanoides L  sesquiterpene lactone  autophagy  lysosomal biogenesis  cytotoxic activity  
Two new monoterpenoid indole alkaloids from the kernels of Kopsia arborea 期刊论文
NATURAL PRODUCT RESEARCH, 2021
作者:  Chen,Chen;  Ding,Xiao;  Han,Lingling;  Zhu,Wentao;  Huang,Kepu;  Hao,Xiaojiang;  Zhang,Yu
浏览  |  Adobe PDF(364Kb)  |  收藏  |  浏览/下载：232/143  |  提交时间：2022/04/02
Apocynaceae  Kopsia arborea  kernels  monoterpene indole alkaloids  OFFICINALIS  
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 卷号: 17, 期号: 11, 页码: 2703-2717
作者:  Wei,Ruiran;  Zhao,Yueqin;  Wang,Juan;  Yang,Xu;  Li,Shunlin;  Wang,Yinyuan;  Yang,Xingzhi;  Fei,Jimin;  Hao,Xiaojiang;  Zhao,Yuhan;  Gui,Liming;  Ding,Xiao
浏览  |  Adobe PDF(9123Kb)  |  收藏  |  浏览/下载：102/15  |  提交时间：2022/04/02
Ferroptosis  Tagitinin c  Ros  Er Stress  Nrf2-ho-1 Pathway  Endoplasmic-reticulum Stress  Er-stress  Oxidative Stress  Tumor-suppressor  Nrf2  Death  Iron  Differentiation  Mechanisms  Resistance  
Cytotoxic Monoterpenoid Indole Alkaloids from Tabernaemontana corymbosa as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020
作者:  Zhang, Yu;  Ding, Xiao;  Yuan, Yu-Xi;  Guo, Ling-Li;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1923Kb)  |  收藏  |  浏览/下载：135/36  |  提交时间：2021/01/05