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The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：249/70  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Novel dual-color drug screening model for GLUT4 translocation in adipocytes 期刊论文
MOLECULAR AND CELLULAR PROBES, 2019, 卷号: 43, 页码: 6-12
作者:  Lu, Yanting;  Ma, Xiuli;  Kong, Qinghua;  Xu, Yuhui;  Hu, Jing;  Wang, Fang;  Qin, Wanying;  Wang, Libin;  Xiong, Wenyong
浏览  |  Adobe PDF(1287Kb)  |  收藏  |  浏览/下载：243/58  |  提交时间：2019/03/18
GLUT4  pHluorin  Screening  Glucose uptake  
Modulation of glucose metabolism by a natural compound from Chloranthus japonicus via activation of AMP-activated protein kinase 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 778
作者:  Hu, Rongkuan;  Yan, Huan;  Fei, Xiaoyan;  Liu, Haiyang;  Wu, Jiarui
浏览  |  Adobe PDF(2283Kb)  |  收藏  |  浏览/下载：265/56  |  提交时间：2017/06/01
RACK1 is required for adipogenesis 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, 卷号: 311, 期号: 5, 页码: C831-C836
作者:  Kong, Qinghua;  Gao, Lan;  Niu, Yanfen;  Gongpan, Pianchou;  Xu, Yuhui;  Li, Yan;  Xiong, Wenyong
浏览  |  Adobe PDF(1017Kb)  |  收藏  |  浏览/下载：326/50  |  提交时间：2017/02/14
Rack1  3t3-l1  Adipogenesis  Wnt  Pi3k-akt-mtor-s6k  
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin;  Zhang, Yu;  Yu, Lijing;  Hu, Kaifeng;  Zhu, Weiliang;  Tong, Qingchun;  Chen, Kaixian;  Guo, Fujiang;  Huang, Cheng;  Li, Yiming
浏览  |  Adobe PDF(841Kb)  |  收藏  |  浏览/下载：253/99  |  提交时间：2016/08/22
Alternative Binding Site  Bavachinin  Canonical Ligand-binding Pocket  Carbohydrate Metabolism  Lipid Metabolism  Pan-ppar Agonist  Synergistic Effects  
Gene Expression and Correlation of Pten and Fabp4 in Liver, Muscle, and Adipose Tissues of Type 2 Diabetes Rats 期刊论文
MEDICAL SCIENCE MONITOR, 2015, 卷号: 21, 期号: 8, 页码: 3616-3621
作者:  Su,Di;  Zhang,Chuan-ling;  Gao,Ying-chun;  Liu,Xiao-ying;  Li,Cai-ping;  Jian Huangfu;  Xiao,Rui
浏览  |  Adobe PDF(265Kb)  |  收藏  |  浏览/下载：166/57  |  提交时间：2016/01/19
Fatty Acid-binding Proteins  Diabetes Mellitus  Pten Phosphohydrolase  Type 2  
Mangiferin and its aglycone, norathyriol, improve glucose metabolism by activation of AMP-activated protein kinase 期刊论文
PHARMACEUTICAL BIOLOGY, 2014, 卷号: 52, 期号: 1, 页码: 68-73
作者:  Wang, Fang;  Yan, Juming;  Niu, Yanfen;  Li, Yan;  Lin, Hua;  Liu, Xu;  Liu, Jikai;  Li, Ling
浏览  |  Adobe PDF(383Kb)  |  收藏  |  浏览/下载：297/65  |  提交时间：2014/04/09
Active Metabolite  Ampk  Insulin Resistance  L6 Muscle Cells  Norathyriol  
Neoalbaconol induces energy depletion and multiple cell death in cancer cells by targeting PDK1-PI3-K/Akt signaling pathway 期刊论文
CELL DEATH & DISEASE, 2013, 卷号: 4, 页码: e804
作者:  Deng, Q.;  Yu, X.;  Xiao, L.;  Hu, Z.;  Luo, X.;  Tao, Y.;  Yang, L.;  Liu, X.;  Chen, H.;  Ding, Z.;  Feng, T.;  Tang, Y.;  Weng, X.;  Gao, J.;  Yi, W.;  Bode, A. M.;  Dong, Z.;  Liu, J.;  Cao, Y.
Adobe PDF(1755Kb)  |  收藏  |  浏览/下载：630/73  |  提交时间：2013/11/12
Neoalbaconol  Pdk1  Pi3-k/akt  Energy Depletion  Cancer Cell Death  
Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2012, 卷号: 75, 期号: 4, 页码: 699-706
作者:  Zhang, Lai-Bin;  Ji, Jun;  Lei, Chun;  Wang, He-Yao;  Zhao, Qin-Shi;  Hou, Ai-Jun
Adobe PDF(393Kb)  |  收藏  |  浏览/下载：502/210  |  提交时间：2012/06/07
Michelia Coriacea  Genetic Diversity  Critically Endangered Plant  Issr Markers  Ssr Markers  Conservation Genetics  Population-genetics  Ssr Markers  Rapd  Issr  Rare  Island  Aflp  Flow  Proteaceae  
New isoprenylated flavonoids and adipogenesis-promoting constituents from Morus notabilis 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 卷号: 21, 期号: 15, 页码: 4441-4446
作者:  Hu, Xiao;  Ji, Jun;  Wang, Meng;  Wu, Jin-Wei;  Zhao, Qin-Shi;  Wang, He-Yao;  Hou, Ai-Jun
Adobe PDF(863Kb)  |  收藏  |  浏览/下载：310/104  |  提交时间：2012/04/10
Morus Notabilis  Isoprenylated Flavonoids  Adipogenesis