| Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa | |
Zhang, Lai-Bin1; Ji, Jun1; Lei, Chun1; Wang, He-Yao2; Zhao, Qin-Shi3 ; Hou, Ai-Jun1
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| 通讯作者 | Hou, AJ (reprint author), Fudan Univ, Sch Pharm, Dept Pharmacognosy, 826 Zhang Heng Rd, Shanghai 201203, Peoples R China, ajhou@shmu.edu.cn |
| 2012-04-01 | |
| 发表期刊 | JOURNAL OF NATURAL PRODUCTS
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| ISSN | 0163-3864 |
| 卷号 | 75期号:4页码:699-706 |
| 摘要 | Ten new isoprenylated flavonol derivatives, dodoviscins A-J (1-10), and seven known compounds (11-17) were isolated from the aerial parts of Dodonaea viscosa. Compounds 1, 2, 4, 5, 7-9, 5,7,4'-trihydroxy-3',5'-bis(3-methyl-2-buten-1-yl)-3-methoxyflavone (11), 5,7,4'-trihydroxy-3',5'-bis(3-methyl-2-buten-1-yl)-3,6-dimethoxyflavone (12), 5,7,4'-trihydroxy-3'-(4-hydroxy-3-methylbutyl)-5'-(3-methyl-2-buten-1-yl)-3,6-dinnethyoxyflavone (13), sakuranetin (14), and blumeatin (15) promoted adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells. Compounds 1, 13, and 15 also enhanced the accumulation of lipid droplets and induced upregulation of the expression of the adipocyte-specific genes aP2 and GLUT4. |
| 关键词 | Michelia Coriacea Genetic Diversity Critically Endangered Plant Issr Markers Ssr Markers Conservation Genetics Population-genetics Ssr Markers Rapd Issr Rare Island Aflp Flow Proteaceae |
| 学科领域 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| DOI | 10.1021/np2009797 |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000303220500028 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/10453 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Fudan Univ, Sch Pharm, Dept Pharmacognosy, Shanghai 201203, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Lai-Bin,Ji, Jun,Lei, Chun,et al. Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(4):699-706. |
| APA | Zhang, Lai-Bin,Ji, Jun,Lei, Chun,Wang, He-Yao,Zhao, Qin-Shi,&Hou, Ai-Jun.(2012).Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa.JOURNAL OF NATURAL PRODUCTS,75(4),699-706. |
| MLA | Zhang, Lai-Bin,et al."Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa".JOURNAL OF NATURAL PRODUCTS 75.4(2012):699-706. |
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