Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa
Zhang, Lai-Bin1; Ji, Jun1; Lei, Chun1; Wang, He-Yao2; Zhao, Qin-Shi3; Hou, Ai-Jun1
2012-04-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号75期号:4页码:699-706
摘要Ten new isoprenylated flavonol derivatives, dodoviscins A-J (1-10), and seven known compounds (11-17) were isolated from the aerial parts of Dodonaea viscosa. Compounds 1, 2, 4, 5, 7-9, 5,7,4'-trihydroxy-3',5'-bis(3-methyl-2-buten-1-yl)-3-methoxyflavone (11), 5,7,4'-trihydroxy-3',5'-bis(3-methyl-2-buten-1-yl)-3,6-dimethoxyflavone (12), 5,7,4'-trihydroxy-3'-(4-hydroxy-3-methylbutyl)-5'-(3-methyl-2-buten-1-yl)-3,6-dinnethyoxyflavone (13), sakuranetin (14), and blumeatin (15) promoted adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells. Compounds 1, 13, and 15 also enhanced the accumulation of lipid droplets and induced upregulation of the expression of the adipocyte-specific genes aP2 and GLUT4.
关键词Michelia Coriacea Genetic Diversity Critically Endangered Plant Issr Markers Ssr Markers Conservation Genetics Population-genetics Ssr Markers Rapd Issr Rare Island Aflp Flow Proteaceae
资助信息program for New Century Excellent Talents in University[NCET-09-0313]; Fudan University
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np2009797
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000303220500028
引用统计
被引频次:19[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/10453
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Fudan Univ, Sch Pharm, Dept Pharmacognosy, Shanghai 201203, Peoples R China
2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
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GB/T 7714
Zhang, Lai-Bin,Ji, Jun,Lei, Chun,et al. Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(4):699-706.
APA Zhang, Lai-Bin,Ji, Jun,Lei, Chun,Wang, He-Yao,Zhao, Qin-Shi,&Hou, Ai-Jun.(2012).Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa.JOURNAL OF NATURAL PRODUCTS,75(4),699-706.
MLA Zhang, Lai-Bin,et al."Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa".JOURNAL OF NATURAL PRODUCTS 75.4(2012):699-706.
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