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题名: Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa
作者: Zhang, Lai-Bin1; Ji, Jun1; Lei, Chun1; Wang, He-Yao2; null(赵勤实)3; Hou, Ai-Jun1
刊名: JOURNAL OF NATURAL PRODUCTS
关键词: Michelia coriacea ; genetic diversity ; critically endangered plant ; ISSR markers ; SSR markers ; CONSERVATION GENETICS ; POPULATION-GENETICS ; SSR MARKERS ; RAPD ; ISSR ; RARE ; ISLAND ; AFLP ; FLOW ; PROTEACEAE
英文摘要: Ten new isoprenylated flavonol derivatives, dodoviscins A-J (1-10), and seven known compounds (11-17) were isolated from the aerial parts of Dodonaea viscosa. Compounds 1, 2, 4, 5, 7-9, 5,7,4'-trihydroxy-3',5'-bis(3-methyl-2-buten-1-yl)-3-methoxyflavone (11), 5,7,4'-trihydroxy-3',5'-bis(3-methyl-2-buten-1-yl)-3,6-dimethoxyflavone (12), 5,7,4'-trihydroxy-3'-(4-hydroxy-3-methylbutyl)-5'-(3-methyl-2-buten-1-yl)-3,6-dinnethyoxyflavone (13), sakuranetin (14), and blumeatin (15) promoted adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells. Compounds 1, 13, and 15 also enhanced the accumulation of lipid droplets and induced upregulation of the expression of the adipocyte-specific genes aP2 and GLUT4.
出版日期: 2012-04-01
卷号: 75, 期号:4, 页码:699-706
语种: 英语
收录类别: SCI ; IC
学科分类: Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
ISSN号: 0163-3864
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/10453
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Fudan Univ, Sch Pharm, Dept Pharmacognosy, Shanghai 201203, Peoples R China
2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China

Recommended Citation:
Zhang, LB; Ji, J; Lei, C; Wang, HY; Zhao, QS; Hou, AJ.Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa,JOURNAL OF NATURAL PRODUCTS,2012,75(4):699-706
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