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Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
浏览  |  Adobe PDF(11543Kb)  |  收藏  |  浏览/下载：4/1  |  提交时间：2024/07/17
Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
作者:  Yan,Ying;  Ran,Xiaoqian;  Wang,Dan;  Zhang,Xiong;  Peng,Mingyou;  Yan,Xiaoyan;  Tang,Lei;  Liang,Hong;  Qin,Xujie;  Di,Ying-Tong;  Luo,Rongcan;  Hao,Xiao-Jiang;  Yao,Yong-Gang
浏览  |  Adobe PDF(1471Kb)  |  收藏  |  浏览/下载：15/4  |  提交时间：2024/07/25
UBIQUITIN-PROTEASOME SYSTEM  ALZHEIMERS-DISEASE  CONSTITUENTS  LIMONOIDS  TFEB  NEURODEGENERATION  
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
作者:  Ran,Xiaoqian;  Lu,Qing-Yun;  Li,Ying-Yao;  Pu,Xue-Xue;  Guo,Yarong;  Yuan,Ming-Rui;  Guan,Shi-Peng;  Sun,Mao;  Jiao,Lijin;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang;  Luo,Rongcan
浏览  |  Adobe PDF(10283Kb)  |  收藏  |  浏览/下载：5/3  |  提交时间：2024/07/30
Euphorbia peplus L  Euphorbiaceae  Ent-abietane diterpenoid  Euphejolkinolide A  Autophagy-lysosomal pathway  ALZHEIMERS-DISEASE  TAU PATHOLOGY  NEURODEGENERATION  DITERPENOIDS  INHIBITION  MECHANISMS  APOPTOSIS  CELASTROL  PROTEIN  SYSTEM  
Iridoid glycosides from Morinda officinalis induce lysosomal biogenesis and promote autophagic flux to attenuate oxidative stress 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2023
作者:  Wang,Yin-Yuan;  Ni,Jian-Cheng;  Zhao,Yue-Qin;  Yang,Xu;  Niu,Zhen-Peng;  Yang,Xing-Zhi;  Dong,Xian-Xiang;  Zhao,Yu-Han;  Hao,Xiao-Jiang;  Ding,Xiao
浏览  |  Adobe PDF(1997Kb)  |  收藏  |  浏览/下载：3/1  |  提交时间：2024/07/31
Iridoid glycosides  Morinda officinalis  lysosomal biogenesis  TFEB/TFE3  antioxidant activity  TRANSCRIPTIONAL CONTROL  TFEB  PHOSPHORYLATION  REVEALS  PATHWAY  
Cytotoxic Monoterpenoid Indole Alkaloids from Tabernaemontana corymbosa as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020
作者:  Zhang, Yu;  Ding, Xiao;  Yuan, Yu-Xi;  Guo, Ling-Li;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1923Kb)  |  收藏  |  浏览/下载：142/38  |  提交时间：2021/01/05
Phenolic derivatives from Garcinia multiflora Champion ex Bentham and their chemotaxonomic significance 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2020
作者:  Yang, Haojie;  Tian, Dongsong;  Zeng, Yanrong;  Huang, Liejun;  Gu, Wei;  Hao, Xiaojiang;  Yuan, Chunmao
浏览  |  Adobe PDF(569Kb)  |  收藏  |  浏览/下载：111/34  |  提交时间：2021/01/05
A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 页码: 9
作者:  Adelakun, Tiwalade A.;  Ding, Xiao;  Ombati, Rose M.;  Zhao, Ning-Dong;  Obodozie-Ofoegbu, Obiageri;  Di, Ying-Tong;  Zhang, Yu;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1037Kb)  |  收藏  |  浏览/下载：330/162  |  提交时间：2019/07/29
Euphorbia fischeriana Steud  highly oxygenated abietanes  phorbol esters  lysosomal biogenesis  
Design, synthesis, and cytotoxic activities of novel hybrids of parthenolide and thiazolidinedione via click chemistry 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 页码: 9
作者:  Qiu, Jie;  Yuan, Chun-Mao;  Wen, Min;  Li, Ya-Nan;  Chen, Juan;  Jian, Jun-You;  Huang, Lie-Jun;  Gu, Wei;  Li, Yan-Mei;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1093Kb)  |  收藏  |  浏览/下载：220/56  |  提交时间：2019/07/29
Parthenolide-thiazolidinedione hybrids  click chemistry  cytotoxic activities  
Protein kinase C controls lysosome biogenesis independently of mTORC1 期刊论文
NATURE CELL BIOLOGY, 2016, 卷号: 18, 期号: 10, 页码: 1065-1077
作者:  Li, Yang;  Xu, Meng;  Ding, Xiao;  Yan, Chen;  Song, Zhiqin;  Chen, Lianwan;  Huang, Xiahe;  Wang, Xin;  Jian, Youli;  Tang, Guihua;  Tang, Changyong;  Di, Yingtong;  Mu, Shuzhen;  Liu, Xuezhao;  Liu, Kai;  Li, Ting;  Wang, Yingchun;  Miao, Long;  Guo, Weixiang;  Hao, Xiaojiang;  Yang, Chonglin
浏览  |  Adobe PDF(4637Kb)  |  收藏  |  浏览/下载：575/154  |  提交时间：2016/12/21
Two Unusual Polycyclic Polyprenylated Acylphloroglucinols, Including a Pair of Enantiomers from Garcinia multiflora 期刊论文
ORGANIC LETTERS, 2015, 卷号: 17, 期号: 9, 页码: 2066-2069
作者:  Fan, Yi-Min;  Yi, Ping;  Li, Yang;  Yan, Chen;  Huang, Tao;  Gu, Wei;  Ma, Yuan;  Huang, Lie-Jun;  Zhang, Jian-Xin;  Yang, Chong-Lin;  Li, Yan;  Yuan, Chun-Mao;  Hao, Xiao-Jiang;  Yuan,CM (reprint author),Key Lab Chem Nat Prod Guizhou Prov,Guiyang 550002,Peoples R China.;  yuanchunmao01@126.com;  haoxj@mail.kib.ac.cn
浏览  |  Adobe PDF(678Kb)  |  收藏  |  浏览/下载：279/117  |  提交时间：2015/07/20