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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
Authors:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Favorite  |  View/Download:90/0  |  Submit date:2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Synthesis of Novel ent-Kaurane-Type Diterpenoid Derivatives Effective for Highly Aggressive Tumor Cells 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 9
Authors:  Hu, Yu;  Li, Xiao-Nian;  Ma, Ze-Jin;  Puno, Pema-Tenzin;  Zhao, Yong;  Zhao, Yan;  Xiao, Ye-Zhi;  Zhang, Wei;  Liu, Jing-Ping
Favorite  |  View/Download:13/0  |  Submit date:2019/03/18
ent-kaurane-type diterpenoid derivatives  antitumor  synthesis  
Structurally diverse diterpenoids from Isodon pharicus 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2018, 卷号: 5, 期号: 15, 页码: 2379-2389
Authors:  Hu, Zheng-Xi;  Xu, Hou-Chao;  Hu, Kun;  Liu, Miao;  Li, Xiao-Nian;  Li, Xing-Ren;  Du, Xue;  Zhang, Yong-Hui;  Puno, Pema-Tenzin;  Sun, Han-Dong
Favorite  |  View/Download:232/0  |  Submit date:2018/09/17
Rabdocoestin B exhibits antitumor activity by inducing G2/M phase arrest and apoptosis in esophageal squamous cell carcinoma 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2018, 卷号: 81, 期号: 3, 页码: 469-481
Authors:  Wang, Jingnan;  Zhang, Zhirong;  Che, Yun;  Yuan, Zuyang;  Lu, Zhiliang;  Li, Yuan;  Wan, Jun;  Sun, Handong;  Chen, Zhaoli;  Pu, Jianxin;  He, Jie
Favorite  |  View/Download:227/0  |  Submit date:2018/05/08
Rabdocoestin b  G2/m Phase Arrest  Apoptosis  Cytotoxicity  Esophageal Squamous Cell Carcinoma  
Scopariusols L-T, nine new ent-kaurane diterpenoids isolated from Isodon scoparius 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2018, 卷号: 16, 期号: 6, 页码: 456-464
Authors:  Jiang Hua-Yi;  Li Xiao-Nian;  Sun Han-Dong;  Zhang Hong-Bin;  Puno, Pema-Tenzin
Favorite  |  View/Download:6/0  |  Submit date:2019/03/29
7 alpha,20-Epoxy-ent-kaurane Diterpenoids from the Aerial Parts of Isodon pharicus 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 1, 页码: 106-116
Authors:  Hu, Zheng-Xi;  Liu, Miao;  Wang, Wei-Guang;  Li, Xiao-Nian;  Hu, Kun;  Li, Xing-Ren;  Du, Xue;  Zhang, Yong-Hui;  Puno, Pema-Tenzin;  Sun, Han-Dong
Favorite  |  View/Download:178/0  |  Submit date:2018/05/08
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
Authors:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Favorite  |  View/Download:107/0  |  Submit date:2018/07/16
Acetyl-macrocalin b  Reactive Oxygen Species  P38 Mapk  Apoptosis  Chk1  Chk2  G2  m Phase Arrest  Nsclc  
Scopariusols L-T, nine new ent-kaurane diterpenoids isolated from Isodon scoparius 期刊论文
FITOTERAPIA, 2018, 卷号: 127, 页码: 74-80
Authors:  Jiang Hua-Yi;  Li Xiao-Nian;  Sun Han-Dong;  Zhang Hong-Bin;  Puno, Pema-Tenzin
Favorite  |  View/Download:58/0  |  Submit date:2018/12/27
链霉菌Streptomyces sp.KIB-H1424中的一个新的烷基间苯二酚类化合物 期刊论文
天然产物研究与开发, 2018, 页码: 8
Authors:  张周鑫;  侯冠雄;  马亚团;  黄建萍;  罗剑英;  杨静;  颜一军;  黄胜雄
Favorite  |  View/Download:104/0  |  Submit date:2018/11/26
链霉菌  次级代谢产物  分离鉴定  烷基间苯二酚  
Bioactive ent-kaurane diterpenoids from Isodon rubescens 期刊论文
PHYTOCHEMISTRY, 2017, 卷号: 143, 页码: 199-207
Authors:  Zhang, Yuan-Yuan;  Jiang, Hua-Yi;  Liu, Miao;  Hu, Kun;  Wang, Wei-Guang;  Du, Xue;  Li, Xiao-Nian;  Pu, Jian-Xin;  Sun, Han-Dong
View  |  Adobe PDF(1170Kb)  |  Favorite  |  View/Download:277/19  |  Submit date:2017/11/20
Isodon Rubescens  Lamiaceae  Cytotoxicity  7  Anti-inflammatory  20-epoxy-ent-kaurane Diterpenoids