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Artemannuols A-C, novel sesquiterpenoid-flavonol hybrids with antihepatoma activity from Artemisia annua 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 26, 页码: 5451-5456
作者:  He,Xiao-Feng;  Wang,Meng-Fei;  Li,Tian-Ze;  Ma,Yun-Bao;  Chen,Ji-Jun
浏览  |  Adobe PDF(556Kb)  |  收藏  |  浏览/下载：58/10  |  提交时间：2024/07/25
Hepatocellular-carcinoma  Aggregation Pheromone  Bug  
Artemongolins A-K, undescribed germacrane-guaiane sesquiterpenoid dimers from Artemisia mongolica and their antihepatoma activities 期刊论文
ARCHIVES OF PHARMACAL RESEARCH, 2023, 卷号: 46, 期号: 9-10, 页码: 782-794
作者:  Shang,Chong;  Ma,Yun-Bao;  Wang,Yuan;  He,Xiao-Feng;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(1281Kb)  |  收藏  |  浏览/下载：52/14  |  提交时间：2024/05/09
Artemisia mongolica  Artemongolins A-K  Sesquiterpenoid dimers  Antihepatoma activity  HEPATOCELLULAR-CARCINOMA  LACTONE  ARGYI  
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 886
作者:  Chen,Yuanzhi;  He,Zhicheng;  Yang,Shuting;  Chen,Cheng;  Xiong,Wenyong;  He,Yingying;  Liu,Shubai
浏览  |  Adobe PDF(4466Kb)  |  收藏  |  浏览/下载：75/11  |  提交时间：2024/05/09
Runt-related transcription factor 1 (RUNX1)  High-grade serous ovarian carcinoma (HGSOC)  Apoptosis  EMT  Clinical therapeutic target  EPITHELIAL-MESENCHYMAL TRANSITIONS  HEPATOCELLULAR-CARCINOMA  TRANSCRIPTION FACTOR  TP53 MUTATIONS  UP-REGULATION  TUMOR-GROWTH  MIGRATION  PROLIFERATION  INVASION  FOXO1  
Cytotoxic and pro-apoptotic effects of botanical drugs derived from the indigenous cultivated medicinal plant Paris polyphylla var. yunnanensis 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1100825
作者:  Yan,Xiu-Xiang;  Zhao,Yan-Qiang;  He,Yun;  Disayathanoowat,Terd;  Pandith,Hataichanok;  Inta,Angkhana;  Yang,Li-Xin
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Paris polyphylla var  yunnanensis  indigenous medicine knowledge  saponins  cytotoxic effects  pro-apoptotic effects  CELL-CYCLE ARREST  STEROIDAL SAPONINS  HEPATOCELLULAR-CARCINOMA  CHEMICAL-CONSTITUENTS  ASSAY  GLYCOSIDES  LEAVES  GROWTH  STEMS  SITES  
Hepatic RACK1 deletion disturbs lipid and glucose homeostasis independently of insulin resistance 期刊论文
JOURNAL OF ENDOCRINOLOGY, 2022, 卷号: 254, 期号: 3, 页码: 151-165
作者:  Qin, Wanying;  Zhang, Ting;  Ge, Mingxia;  Zhou, Huimin;  Xu, Yuhui;  Mu, Rongfang;  Huang, Chaoguang;  Liu, Daowei;  Huang, Bangrui;  Wang, Qian;  Kong, Qinghua;  Kong, Qingpeng;  Li, Fei;  Xiong, Wenyong
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RACK1  bile acid  glucose metabolism  insulin sensitivity  ENDOPLASMIC-RETICULUM STRESS  C-KINASE 1  HEPATOCELLULAR-CARCINOMA  STEROL 12-ALPHA-HYDROXYLASE  DOWN-REGULATION  ER STRESS  KAPPA-B  RECEPTOR  ACTIVATION  GROWTH  
New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1648-1666
作者:  Su,Lihua;  Zhang,Xintian;  Ma,Yunbao;  Geng,Changan;  Huang,Xiaoyan;  Hu,Jing;  Li,Tianze;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xuemei;  Chen,Ji-Jun
浏览  |  Adobe PDF(4074Kb)  |  收藏  |  浏览/下载：153/53  |  提交时间：2022/04/02
Guaianolide dimers  Artematrolides AeR  Artemisia atrovirens  Cytotoxicity  Cell cycle  Apoptosis  FARNESYL-PROTEIN TRANSFERASE  CELL-CYCLE ARREST  HEPATOCELLULAR-CARCINOMA  GUAIANOLIDES  LACTONES  INHIBITORS  ARTEMINOLIDE  APOPTOSIS  ARGYI  HELA  
Diterpenoids from Isodon species: an update 期刊论文
NATURAL PRODUCT REPORTS, 2017, 卷号: 34, 期号: 9, 页码: 1090-1140
作者:  Liu, Miao;  Wang, Wei-Guang;  Sun, Han-Dong;  Pu, Jian-Xin
浏览  |  Adobe PDF(10292Kb)  |  收藏  |  浏览/下载：314/39  |  提交时间：2017/10/23
Ent-kaurane Diterpenoids  Japonica Var. Glaucocalyx  Nf-kappa-b  Hepatocellular-carcinoma Cells  C-h Functionalization  Dna-binding Activity  Serra Maxim. Hara  Maoecrystal-v  Abietane Diterpenoids  Chemical-constituents  
Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells 期刊论文
CELL DEATH & DISEASE, 2014, 卷号: 5, 页码: e1137, e1137
作者:  Liao, Y-J;  Bai, H-Y;  Li, Z-H;  Zou, J.;  Chen, J-W;  Zheng, F.;  Zhang, J-X;  Mai, S-J;  Zeng, M-S;  Sun, H-D;  Pu, J-X;  Xie, D.
浏览  |  Adobe PDF(5082Kb)  |  收藏  |  浏览/下载：627/58  |  提交时间：2014/05/16
Longikaurin a  Hepatocellular Carcinoma  Cell Cycle Arrest  Apoptosis  Skp2  
Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2011, 卷号: 164, 期号: 2B, 页码: 731-742
作者:  Wang, Ning;  Pan, Weidong;  Zhu, Meifen;  Zhang, Maosheng;  Hao, Xiaojian;  Liang, Guangyi;  Feng, Yibin
浏览  |  Adobe PDF(1960Kb)  |  收藏  |  浏览/下载：432/108  |  提交时间：2012/07/25
Fangchinoline  Autophagy  P53  Sestrin2  Hepatocellular Carcinoma  Ampk