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通络方剂对糖尿病大鼠心、肾、腹主动脉血管紧张素水平的影响 期刊论文
实验研究, 3111, 期号: 0, 页码: 139-141
Authors:  宋迎香;  邹俊杰;  李文桐;  张春阳;  刘岩孙;  夏培金;  亮亮;  曲卫;  汤玮;  刘明;  刘志民
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糖尿病  实验性  血管紧张素  通络方剂  大鼠  
Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 39-46
Authors:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Uncaria rhynchophylla  Catechin  Melatonin receptors  Metabolites  Antidepressant activity  
Nukiangendines A and B, two novel 13,14-seco-abietanes from Abies nukiangensis 期刊论文
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 10, 页码: 751-753
Authors:  Li, Yong-Li;  Zhang, Qiang;  Wu, Jian-Jun;  Xue, Li-Jun;  Chen, Li-Ming;  Tian, Jun-Mian;  Xu, Zhuo-Ni;  Chen, Ying;  Yang, Xian-Wen;  Hao, Xiao-Jiang;  Li, Jie
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Abies nukiangensis  seco-Abietane  Diterpene  Antiviral  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
Authors:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
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Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
Authors:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
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Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Five new alkaloids from Aconitum apetalum (Ranunculaceae) 期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 29, 页码: 6-11
Authors:  Hu, Zhan-Xing;  Tang, Hong-Yu;  Yan, Xiao-Hui;  Zeng, Yan-Rong;  Aisa, Haji Aker;  Zhang, Yu;  Hao, Xiao-Jiang
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Aconitum apetalum  Diterpenoid alkaloids  Aporphine alkaloids  Anti-TMV  Antimicrobial  
Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic Streptomyces 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 2, 页码: 177-182
Authors:  Zhang, Zhouxin;  Cao, Pei;  Shang, Ning-Ning;  Yang, Jing;  Wang, Li;  Yan, Yijun;  Huang, Sheng-Xiong
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Chepraecoxins A-G, ent-Kaurane Diterpenoids with alpha-Glucosidase Inhibitory Activities from Chelonopsis praecox 期刊论文
FITOTERAPIA, 2019, 卷号: 132, 页码: 60-67
Authors:  Deng, Zhen-Tao;  Geng, Chang-An;  Yang, Tong-Hua;  Xiang, Chun-Lei;  Chen, Ji-Jun
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Chelonopsis praecox  chepraecoxins A-G  ent-kaurane diterpenoids  alpha-glucosidase  
Synthesis of Novel ent-Kaurane-Type Diterpenoid Derivatives Effective for Highly Aggressive Tumor Cells 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 9
Authors:  Hu, Yu;  Li, Xiao-Nian;  Ma, Ze-Jin;  Puno, Pema-Tenzin;  Zhao, Yong;  Zhao, Yan;  Xiao, Ye-Zhi;  Zhang, Wei;  Liu, Jing-Ping
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ent-kaurane-type diterpenoid derivatives  antitumor  synthesis  
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
Authors:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
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Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization