KIB OpenIR

浏览/检索结果: 共128条,第1-10条 帮助

已选(0)清除 条数/页:   排序方式:
Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating [4+2] cycloaddition and target differentiation of enantiomers 期刊论文
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 4
作者:  He, Tao-Bin;  Yan, Bing-Chao;  Zhou, Yuan-Fei;  Sang, Yue-Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Wang, Chu;  Xue, Xiao-Song;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(3322Kb)  |  收藏  |  浏览/下载:125/37  |  提交时间:2024/05/09
DIELS-ALDER REACTION  BIOMIMETIC SYNTHESES  EFFICIENT ACCESS  DEHYDROGENATION  CYCLOHEXANONES  BIOSYNTHESIS  CONVERSION  OXIDATION  DYNAMICS  PHENOLS  
Phylogenomic insights into the reticulate evolution of Camellia sect. Paracamellia Sealy (Theaceae) 期刊论文
JOURNAL OF SYSTEMATICS AND EVOLUTION, 2023
作者:  Qin,Sheng-Yuan;  Chen,Kai;  Zhang,Wen-Ju;  Xiang,Xiao-Guo;  Zuo,Zheng-Yu;  Guo,Cen;  Zhao,Yao;  Li,Lin-Feng;  Wang,Yu-Guo;  Song,Zhi-Ping;  Yang,Ji;  Yang,Xiao-Qiang;  Zhang,Jian;  Jin,Wei-Tao;  Wen,Qiang;  Zhao,Song-Zi;  Chen,Jia-Kuan;  Li,De-Zhu;  Rong,Jun
浏览  |  Adobe PDF(2146Kb)  |  收藏  |  浏览/下载:62/14  |  提交时间:2024/07/10
Camellia oleifera  hybridization  phylogenomics  plastome  polyploidization  transcriptome  EVERGREEN BROADLEAVED FORESTS  HISTORY  DYNAMICS  OLEIFERA  CHINA  PHYLOGEOGRAPHY  ALIGNMENT  TREE  
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction 期刊论文
NATURE CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 4, 页码: 468-+
作者:  Guo,Yingjie;  Zhang,Huan;  Yan,Chen;  Shen,Birong;  Zhang,Yue;  Guo,Xiangyang;  Sun,Sha;  Yu,Fan;  Yan,Jiayun;  Liu,Ronghe;  Zhang,Qianping;  Zhang,Di;  Liu,Haiyang;  Liu,Yang;  Zhang,Yaoyao;  Li,Wenlei;  Qin,Jiangyu;  Lv,He;  Wang,Zhaoxia;  Yuan,Yun;  Yang,Jie-Feng;  Zhong,Ya-Ting;  Gao,Song;  Zhou,Bing;  Liu,Lei;  Kong,Deling;  Hao,Xiaojiang;  Hu,Junjie;  Chen,Quan
浏览  |  Adobe PDF(25423Kb)  |  收藏  |  浏览/下载:77/25  |  提交时间:2024/07/25
ENDOPLASMIC-RETICULUM  PROVIDE INSIGHT  MITOFUSIN 2  MFN1  DYNAMICS  REQUIRES  DEFECTS  FISSION  CELLS  
Heterodimers with a cucurbitane-type triterpenoid skeleton from the branches of Elaeocarpus dubius 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 207, 页码: 113581
作者:  Hu,Dong-Bao;  Wei,Shu-Ya;  Yang,Jun;  Zhang,Dong-Dong;  Duan,Xiao-Yan;  Yan,Hui;  Yang,Xing-Zhi;  Bai,Xue;  Luo,Ji-Feng;  Yang,Jing-Hua;  Wang,Yun-Song;  Wang,Yue-Hu
浏览  |  Adobe PDF(1617Kb)  |  收藏  |  浏览/下载:30/9  |  提交时间:2024/07/25
Elaeocarpus dubius  Elaeocarpaceae  Cucurbitacins  Antioxidant  Neuroprotective  CONSTITUENTS  ELUCIDATION  GLYCOSIDES  
A clue to the evolutionary history of modern East Asian flora: Insights from phylogeography and diterpenoid alkaloid distribution pattern of the Spiraea japonica complex 期刊论文
MOLECULAR PHYLOGENETICS AND EVOLUTION, 2023, 卷号: 184, 页码: 107772
作者:  Luo,Dong;  Song,Min-shu;  Xu,Bo;  Zhang,Yu;  Zhang,Jian-wen;  Ma,Xiang-guang;  Hao,Xiao jiang;  Sun,Hang
浏览  |  Adobe PDF(12334Kb)  |  收藏  |  浏览/下载:93/17  |  提交时间:2024/07/25
ampliative Spiraea japonica complex  East Asian flora  Transition belt  Phylogeography  Diterpenoid alkaloids  MOLECULAR PHYLOGEOGRAPHY  SECONDARY METABOLITES  HENGDUAN MOUNTAINS  QUATERNARY CLIMATE  PLANT DIVERSITY  ROSACEAE  DNA  CHLOROPLAST  COALESCENT  CHINA  
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan;  Yang,Ren-Zhi;  Zhang,Hong-Sheng;  Cai,Xiang-Hai;  Wang,Jing-Wen;  Xie,Xiao-Yong;  Song,Li;  Luo,Biao;  Chen,Jian;  Chen,Long;  Deng,Xiao-Juan;  Chen,Guo-Jun
浏览  |  Adobe PDF(6685Kb)  |  收藏  |  浏览/下载:110/18  |  提交时间:2024/05/09
conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER  
Global consortium for the classification of fungi and fungus-like taxa 期刊论文
MYCOSPHERE, 2023, 卷号: 14, 期号: 1, 页码: 1960-2012
作者:  Hyde,K. D.;  Abdel-Wahab,M. A.;  Abdollahzadeh,J.;  Abeywickrama,P. D.;  Absalan,S.;  Afshari,N.;  Ainsworth,A. M.;  Akulov,O. Y.;  Aleoshin,V. V.;  Al-Sadi,A. M.;  Alvarado,P.;  Alves,A.;  Alves-Silva,G.;  Amalfi,M.;  Amira,Y.;  Amuhenage,T. B.;  Anderson,J. L.;  Antonin,V;  Aouali,S.;  Aptroot,A.;  Apurillo,C. C. S.;  Araujo,J. P. M.;  Ariyawansa,H. A.;  Armand,A.;  Arumugam,E.;  Asghari,R.;  Assis,D. M. A.;  Atienza,V;  Avasthi,S.;  Azevedo,E.;  Bahkali,A. H.;  Bakhshi,M.;  Banihashemi,Z.;  Bao,D. F.;  Baral,H. O.;  Barata,M.;  Barbosa,F. R.;  Barbosa,R. N.;  Barreto,R. W.;  Baschien,C.;  Belamesiatseva,D. B.;  Bennett Reuel,M.;  Bera,I;  Bezerra,J. D. P.;  Bezerra,J. L.;  Bhat,D. J.;  Bhunjun,C. S.;  Bianchinotti,M.,V;  Blaszkowski,J.;  Blondelle,A.;  Boekhout,T.;  Bonito,G.;  Boonmee,S.;  Boonyuen,N.;  Bregant,C.;  Buchanan,P.;  Bundhun,D.;  Burgaud,G.;  Burgess,T.;  Buyck,B.;  Cabarroi-Hernandez,M.;  Caceres,M. E. S.;  Caeiro,M. F.;  Cai,L.;  Cai,M. F.;  Calabon,M. S.;  Calaca,F. J. S.;  Callalli,M.;  Camara,M. P. S.;  Cano-Lira,J. F.;  Cantillo,T.;  Cao,B.;  Carlavilla,J. R.;  Carvalho,A.;  Castaneda-Ruiz,R. F.;  Castlebury,L.;  Castro-Jauregui,O.;  Catania,M. D.,V;  Cavalcanti,L. H.;  Cazabonne,J.;  Cedeno-Sanchez,M. L.;  Chaharmiri-Dokhaharani,S.;  Chaiwan,N.;  Chakraborty,N.;  Chaverri,P.;  Cheewangkoon,R.;  Chen,C.;  Chen,C. Y.;  Chen,K. H.;  Chen,J.;  Chen,Q.;  Chen,W. H.;  Chen,Y. P.;  Chethana,K. W. T.;  Coleine,C.;  Conde,T. O.;  Corazon-Guivin,M. A.;  Cortes-Perez,A.;  Costa-Rezende,D. H.;  Courtecuisse,R.;  Crouch,J. A.;  Crous,P. W.;  Cui,B. K.;  Cui,Y. Y.;  da Silva,D. K. A.;  da Silva,G. A.;  da Silva,I. R.;  da Silva,R. M. F.;  da Silva Santos,A. C.;  Dai,D. Q.;  Dai,Y. C.;  Damm,U.;  Darmostuk,V;  Zoha,Daroodi;  Das,K.;  Das,K.;  Davoodian,N.;  Davydov,E. A.;  Dayarathne,M. C.;  Decock,C.;  de Groot,M. D.;  De Kesel,A.;  dela Cruz,T. E. E.;  De Lange,R.;  Delgado,G.;  Denchev,C. M.;  Denchev,T. T.;  de Oliveira,N. T.;  de Silva,N.,I;  de Souza,F. A.;  Dentinger,B.;  Devadatha,B.;  Dianese,J. C.;  Dima,B.;  Diniz,A. G.;  Dissanayake,A. J.;  Dissanayake,L. S.;  Dogan,H. H.;  Doilom,M.;  Dolatabadi,S.;  Dong,W.;  Dong,Z. Y.;  Dos Santos,L. A.;  Drechsler-Santos,E. R.;  Du,T. Y.;  Dubey,M. K.;  Dutta,A. K.;  Egidi,E.;  Elliott,T. F.;  Elshahed,M. S.;  Erdogdu,M.;  Ertz,D.;  Etayo,J.;  Evans,H. C.;  Fan,X. L.;  Fan,Y. G.;  Fedosova,A. G.;  Fell,J.;  Fernandes,I;  Firmino,A. L.;  Fiuza,P. O.;  Flakus,A.;  Fragoso de Souza,C. A.;  Frisvad,J. C.;  Fryar,S. C.;  Gabaldon,T.;  Gajanayake,A. J.;  Galindo,L. J.;  Gannibal,P. B.;  Garcia,D.;  Garcia-Sandoval,S. R.;  Garrido-Benavent,I;  Garzoli,L.;  Gautam,A. K.;  Ge,Z-W;  Gene,D. J.;  Gentekaki,E.;  Ghobad-Nejhad,M.;  Giachini,A. J.;  Gibertoni,T. B.;  Goes-Neto,A.;  Gomdola,D.;  Gomes de Farias,A. R.;  Gorjon,S. P.;  Goto,B. T.;  Granados-Montero,M. M.;  Griffith,G. W.;  Groenewald,J. Z.;  Groenewald,M.;  Grossart,H. P.;  Gueidan,C.;  Gunarathne,A.;  Gunaseelan,S.;  Gusmao,L. F. P.;  Gutierrez,A. C.;  Guzman-Davalos,L.;  Haelewaters,D.;  Halling,R.;  Han,Y. F.;  Hapuarachchi,K. K.;  Harder,C. B.;  Harrington,T. C.;  Hattori,T.;  He,M. Q.;  He,S.;  He,S. H.;  Healy,R.;  Herandez-Restrepo,M.;  Heredia,G.;  Hodge,K. T.;  Holgado-Rojas,M.;  Hongsanan,S.;  Horak,E.;  Hosoya,T.;  Houbraken,J.;  Huang,S. K.;  Huanraluek,N.;  Hur,J. S.;  Hurdeal,V. G.;  Hustad,V. P.;  Iotti,M.;  Iturriaga,T.;  Jafar,E.;  Janik,P.;  Jany,J. L.;  Jayalal,R. G. U.;  Jayasiri,S. C.;  Jayawardena,R. S.;  Jeewon,R.;  Jeronimo,G. H.;  Jesus,A. L.;  Jin,J.;  Johnston,P. R.;  Jones,E. B. G.;  Joshi,Y.;  Justo,A.;  Kaishian,P.;  Kakishima,M.;  Kaliyaperumal,M.;  Kang,G. P.;  Kang,J. C.;  Karakehian,J. M.;  Karimi,O.;  Karpov,S. A.;  Karunarathna,S. C.;  Kaufmann,M.;  Kemler,M.;  Kezo,K.;  Khyaju,S.;  Kirchmair,M.;  Kirk,P. M.;  Kitaura,M. J.;  Klawonn,I;  Kolarik,M.;  Kong,A.;  Kuhar,F.;  Kukwa,M.;  Kumar,S.;  Kusan,I;  Lado,C.;  Larsson,K. H.;  Latha,K. P. D.;  Lee,H. B.;  Leonardi,M.;  Leontyev,D. L.;  Lestari,A. S.;  Li,C. J. Y.;  Li,D. W.;  Li,H.;  Li,H. Y.;  Li,L.;  Li,Q. R.;  Li,Q.;  Li,W. L.;  Li,Y.;  Li,Y. C.;  Li,Y. X.;  Liao,C. F.;  Liimatainen,K.;  Lim,Y. W.;  Lin,C. G.;  Linaldeddu,B. T.;  Linde,C. C.;  Linn,M. M.;  Liu,F.;  Liu,J. K.;  Liu,N. G.;  Liu,S.;  Liu,S. L.;  Liu,X. F.;  Liu,X. Y.;  Liu,X. Z.;  Liu,Z. B.;  Lu,L.;  Lu,Y. Z.;  Luangharn,T.;  Luangsa-ard,J. J.;  Lumbsch,H. T.;  Lumyong,S.;  Luo,L.;  Luo,M.;  Luo,Z. L.;  Ma,J.;  Machado,A. R.;  Madagammana,A. D.;  Madrid,H.;  Magurno,F.;  Magyar,D.;  Mahadevan,N.;  Maharachchikumbura,S. S. N.;  Maimaiti,Y.;  Malosso,E.;  Manamgoda,D. S.;  Manawasinghe,I. S.;  Mapook,A.;  Marasinghe,D. S.;  Mardones,M.;  Marin-Felix,Y.;  Marquez,R.;  Masigol,H.;  Matocec,N.;  May,T. W.;  McKenzie,E. H. C.;  Meiras-Ottoni,A.;  Melo,R. F. R.;  Mendes-Alvarenga,R. L.;  Mendieta,S.;  Meng,Q. F.;  Menkis,A.;  Menolli,N.,Jr.;  Mesic,A.;  Meza Calvo,J. G.;  Mikhailov,K.,V;  Miller,S. L.;  Moncada,B.;  Moncalvo,J. M.;  Monteiro,J. S.;  Monteiro,M.;  Mora-Montes,H. M.;  Moreau,P. A.;  Mueller,G. M.;  Mukhopadyay,S.;  Murugadoss,R.;  Nagy,L. G.;  Najafiniya,M.;  Nanayakkara,C. M.;  Nascimento,C. C.;  Nei,Y.;  Neves,M. A.;  Neuhauser,S.;  Niego,A. G. T.;  Nilsson,R. H.;  Niskanen,T.;  Niveiro,N.;  Noorabadi,M. T.;  Noordeloos,M. E.;  Norphanphoun,C.;  Nunez Otano,N. B.;  O'Donnell,R. P.;  Oehl,F.;  Olariaga,I;  Orlando,O. P.;  Pang,K. L.;  Papp,V;  Pawlowska,J.;  Peintner,U.;  Pem,D.;  Pereira,O. L.;  Perera,R. H.;  Perez-Moreno,J.;  Perez-Ortega,S.;  Peter,G.;  Phillips,A. J. L.;  Phonemany,M.;  Phukhamsakda,C.;  Phutthacharoen,K.;  Piepenbring,M.;  Pires-Zottarelli,C. L. A.;  Poinar,G.;  Posta,A.;  Prieto,M.;  Promputtha,I;  Quandt,C. A.;  Radek,R.;  Rahnama,K.;  Raj,K. N. A.;  Rajeshkumar,K. C.;  Rama,T.;  Rambold,G.;  Ramirez-Cruz,V;  Rasconi,S.;  Rathnayaka,A. R.;  Raza,M.;  Ren,G. C.;  Robledo,G. L.;  Rodriguez-Flakus,P.;  Ronikier,A.;  Rossi,W.;  Ryberg,M.;  Ryvarden,L. R.;  Salvador-Montoya,C. A.;  Samant,B.;  Samarakoon,B. C.;  Samarakoon,M. C.;  Sanchez-Castro,I;  Sanchez-Garcia,M.;  Sandoval-Denis,M.;  Santamaria,B.;  Santiago,A. L. C. M. A.;  Sarma,V. V.;  Savchenko,A.;  Savchenko,K.;  Saxena,R. K.;  Scholler,M.;  Schoutteten,N.;  Seifollahi,E.;  Selbmann,L.;  Selcuk,F.;  Senanayake,I. C.;  Seto,K.;  Shabashova,T. G.;  Shen,H. W.;  Shen,Y. M.;  Silva-Filho,A. G. S.;  Simmons,D. R.;  Singh,R.;  Sir,E. B.;  Song,C. G.;  Souza-Motta,C. M.;  Sruthi,O. P.;  Stadler,M.;  Stchigel,A. M.;  Stemler,J.;  Stephenson,S. L.;  Strassert,J. F. H.;  Su,H. L.;  Su,L.;  Suetrong,S.;  Sulistyo,B.;  Sun,Y. F.;  Sun,Y. R.;  Svantesson,S.;  Sysouphanthong,P.;  Takamatsu,S.;  Tan,T. H.;  Tanaka,K.;  Tang,A. M. C.;  Tang,X.;  Tanney,J. B.;  Tavakol,N. M.;  Taylor,J. E.;  Taylor,P. W. J.;  Tedersoo,L.;  Tennakoon,D. S.;  Thamodini,G. K.;  Thines,M.;  Thiyagaraja,V;  Thongklang,N.;  Tiago,P.,V;  Tian,Q.;  Tian,W. H.;  Tibell,L.;  Tibell,S.;  Tibpromma,S.;  Tkalcec,Z.;  Tomsovsky,M.;  Toome-Heller,M.;  Torruella,G.;  Tsurykau,A.;  Udayanga,D.;  Ulukapi,M.;  Untereiner,W. A.;  Uzunov,B. A.;  Valle,L. G.;  Van Caenegem,W.;  Van den Wyngaert,S.;  Van Vooren,N.;  Velez,P.;  Verma,R. K.;  Vieira,L. C.;  Vieira,W. A. S.;  Vizzini,A.;  Walker,A.;  Walker,A. K.;  Wanasinghe,D. N.;  Wang,C. G.;  Wang,K.;  Wang,S. X.;  Wang,X. Y.;  Wang,Y.;  Wannasawang,N.;  Wartchow,F.;  Wei,D. P.;  Wei,X. L.;  White,J. F.;  Wijayawardene,N. N.;  Wijesinghe,S. N.;  Wijesundara,D. S. A.;  Wisitrassameewong,K.;  Worthy,F. R.;  Wu,F.;  Wu,G.;  Wu,H. X.;  Wu,N.;  Wu,W. P.;  Wurzbacher,C.;  Xiao,Y. P.;  Xiong,Y. R.;  Xu,B.;  Xu,L. J.;  Xu,R.;  Xu,R. F.;  Xu,R. J.;  Xu,T. M.;  Yakovchenko,L.;  Yan,J. Y.;  Yang,H. D.;  Yang,J.;  Yang,Z. L.;  Yang,Y. H.;  Yapa,N.;  Yasanthika,E.;  Youssef,N. H.;  Yu,F. M.;  Yu,Q.;  Yu,X. D.;  Yu,Y. X.;  Yu,Z. F.;  Yuan,H. S.;  Yuan,Y.;  Yurkov,A.;  Zafari,D.;  Zamora,J. C.;  Zare,R.;  Zeng,M.;  Zeng,N. K.;  Zeng,X. Y.;  Zhang,F.;  Zhang,H.;  Zhang,J. F.;  Zhang,J. Y.;  Zhang,Q. Y.;  Zhang,S. N.;  Zhang,W.;  Zhang,Y.;  Zhang,Y. X.;  Zhao,C. L.;  Zhao,H.;  Zhao,Q.;  Zhao,R. L.;  Zhou,L. W.;  Zhou,M.;  Zhurbenko,M. P.;  Zin,H. H.;  Zucconi,L.
浏览  |  Adobe PDF(1105Kb)  |  收藏  |  浏览/下载:196/30  |  提交时间:2024/05/09
classification  nomenclature  scientific criticism  taxonomy  LEVEL PHYLOGENETIC CLASSIFICATION  INCORPORATING ANAMORPHIC FUNGI  FATTY-ACID-COMPOSITION  DNA-SEQUENCE DATA  NATURAL CLASSIFICATION  LEAF-LITTER  SPECIES RECOGNITION  IDENTIFICATION  NOMENCLATURE  TREE  
The protective effect of Allium chinense on anti-cerebral anoxia through regulating NLRP3/NF-?B 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2023, 卷号: 196, 页码: 116499
作者:  Xiao,Xia;  Liu,Yang-Yang;  Yan,Xiao-Jun;  Wang,Xiao-Na;  Hu,Bin-Yuan;  Chen,Song;  Zhu,Yan-Yan;  Wang,Zhao-Jie;  Xie,Tian-Zhen;  He,Ying-Jie;  Zhao,Li-Xing;  Zhao,Yun-Li;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2824Kb)  |  收藏  |  浏览/下载:26/8  |  提交时间:2024/07/30
Allium chinense  Cerebral anoxia  Intracellular reactive oxygen species  NLRP3  NF-?B  Nutritional strategy  ACID  MITOCHONDRIA  CONTRIBUTES  METALATION  INHIBITORS  SAPONINS  DAMAGE  
A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids 期刊论文
PLANT PHYSIOLOGY, 2022, 卷号: 188, 期号: 3, 页码: 1496-1506
作者:  Song,Jiao-Jiao;  Fang,Xin;  Li,Chen-Yi;  Jiang,Yan;  Li,Jian-Xu;  Wu,Sheng;  Guo,Juan;  Liu,Yan;  Fan,Hang;  Huang,Yan-Bo;  Wei,Yu-Kun;  Kong,Yu;  Zhao,Qing;  Xu,Jing-Jing;  Hu,Yong-Hong;  Chen,Xiao-Ya;  Yang,Lei
收藏  |  浏览/下载:133/0  |  提交时间:2022/04/02
MOLECULAR-CLONING  BIOSYNTHESIS  TANSHINONES  EVOLUTION  CYTOTOXICITY  SUPERFAMILY  OXYGENASES  APOPTOSIS  SYNTHASE  
Detailed Structural Analysis of the Immunoregulatory Polysaccharides from the Mycobacterium Bovis BCG 期刊论文
MOLECULES, 2022, 卷号: 27, 期号: 17, 页码: 5691
作者:  Luo, Lan;  Song, Xuemei;  Chang, Xiao;  Huang, Sheng;  Zhou, Yunxi;  Yang, Shengmei;  Zhu, Yan;  Zhang, Lanyan;  Wu, Yongsheng;  Zhang, Junyin;  Zhou, Zhipeng;  Wu, Mingyi
浏览  |  Adobe PDF(2941Kb)  |  收藏  |  浏览/下载:82/11  |  提交时间:2024/04/30
active ingredients  polysaccharide purification  glucan  mannan  immunomodulator  BACILLUS-CALMETTE-GUERIN  (BCG)-INDUCED MACROPHAGE CYTOTOXICITY  IMMUNOMODULATORY ACTIVITY  MALDI-TOF  INTERLEUKIN-10  ACTIVATION  IMMUNITY  GLUCANS  SULFATE  MANNAN