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Characterization and protein engineering of glycosyltransferases for the biosynthesis of diverse hepatoprotective cycloartane-type saponins in Astragalus membranaceus 期刊论文
PLANT BIOTECHNOLOGY JOURNAL, 2023
作者:  Chen,Kuan;  Zhang,Meng;  Gao,Baihan;  Hasan,Aobulikasimu;  Li,Junhao;  Bao,Yang'oujie;  Fan,Jingjing;  Yu,Rong;  Yi,Yang;  Agren,Hans;  Wang,Zilong;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
浏览  |  Adobe PDF(5002Kb)  |  收藏  |  浏览/下载:129/26  |  提交时间:2024/05/09
astragalosides  biosynthesis  glycosyltransferases  protein engineering  Astragalus membranaceus  FUNCTIONAL-CHARACTERIZATION  UDP-GLYCOSYLTRANSFERASES  CARBON-TETRACHLORIDE  PROTOPANAXATRIOL  PHARMACOLOGY  GENERATION  CHEMISTRY  ACCURACY  PATHWAY  
Anticarin-beta shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2268-2279
作者:  Wang, Gan;  Zhang, Min;  Meng, Ping;  Long, Chengbo;  Luo, Xiaodong;  Yang, Xingwei;  Wang, Yunfei;  Zhang, Zhiye;  Mwangi, James;  Kamau, Peter Muiruri;  Dai, Zhi;  Ke, Zunfu;  Zhang, Yi;  Chen, Wenlin;  Zhao, Xudong;  Ge, Fei;  Lv, Qiumin;  Rong, Mingqiang;  Li, Dongsheng;  Jin, Yang;  Sheng, Xia;  Lai, Ren
浏览  |  Adobe PDF(4759Kb)  |  收藏  |  浏览/下载:104/19  |  提交时间:2024/04/30
Proteostasis  CCT  TRiC  Osteosarcoma  STAT3  Anticarin-beta  PDX model  CYTOSOLIC CHAPERONIN  CANCER-CELLS  COMPLEX  EXPRESSION  SURVIVAL  PROTEIN  TUBULIN  GROWTH  
Genomes shed light on the evolution of Begonia, a mega-diverse genus 期刊论文
NEW PHYTOLOGIST, 2022, 卷号: 234, 期号: 1, 页码: 295-310
作者:  Li, Lingfei;  Chen, Xiaoli;  Fang, Dongming;  Dong, Shanshan;  Guo, Xing;  Li, Na;  Campos-Dominguez, Lucia;  Wang, Wenguang;  Liu, Yang;  Lang, Xiaoan;  Peng, Yang;  Tian, Daike;  Thomas, Daniel C.;  Mu, Weixue;  Liu, Min;  Wu, Chenyu;  Yang, Ting;  Zhang, Suzhou;  Yang, Leilei;  Yang, Jianfen;  Liu, Zhong-Jian;  Zhang, Liangsheng;  Zhang, Xingtan;  Chen, Fei;  Jiao, Yuannian;  Guo, Yalong;  Hughes, Mark;  Wang, Wei;  Liu, Xiaofei;  Zhong, Chunmei;  Li, Airong;  Sahu, Sunil Kumar;  Yang, Huanming;  Wu, Ernest;  Sharbrough, Joel;  Lisby, Michael;  Liu, Xin;  Xu, Xun;  Soltis, Douglas E.;  Van de Peer, Yves;  Kidner, Catherine;  Zhang, Shouzhou;  Liu, Huan
浏览  |  Adobe PDF(3357Kb)  |  收藏  |  浏览/下载:133/33  |  提交时间:2024/03/11
AmAT19, an acetyltransferase from Astragalus membranaceus, catalyses specific 6 alpha-OH acetylation for tetracyclic triterpenes and steroids 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 33, 页码: 7186-7189
作者:  Wang,Linlin;  Chen,Kuan;  Wang,Zilong;  Yi,Yang;  Zhang,Meng;  Hasan,Aobulikasimu;  Kuang,Yi;  Shaker,Sharpkate;  Yu,Rong;  Wang,Haotian;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
收藏  |  浏览/下载:107/0  |  提交时间:2022/04/02
ACYLATION  ACYLTRANSFERASE  CYCLOASTRAGENOL  BAHD  
Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans 期刊论文
CELL CALCIUM, 2021, 卷号: 93, 页码: 102327
作者:  Yang,Zhong-Lin;  Chen,Jian-Ning;  Lu,Yu-Yang;  Lu,Min;  Wan,Qin-Li;  Wu,Gui-Sheng;  Luo,Huai-Rong
浏览  |  Adobe PDF(4473Kb)  |  收藏  |  浏览/下载:159/53  |  提交时间:2022/04/02
Inositol polyphosphates  Inositol polyphosphate multikinase  Type I inositol 5-phosphatase  Development  Calcium signaling  Defecation rhythm  C. elegans  C-ELEGANS  PHOSPHOLIPASE-C  CALCIUM  1,4,5-TRISPHOSPHATE  CALCINEURIN  KINASE  IDENTIFICATION  TRISPHOSPHATE  METABOLISM  RECEPTOR  
Reassessment of Bournea Oliver (Gesneriaceae) based on molecular and palynological evidence 期刊论文
PHYTOKEYS, 2020
作者:  Chen, Wen-Hong;  Zhang, Ya-Mei;  Guo, Shi-Wei;  Zhang, Zhi-Rong;  Chen, Li;  Shui, Yu-Min
浏览  |  Adobe PDF(2275Kb)  |  收藏  |  浏览/下载:227/42  |  提交时间:2021/01/05
A new species of Begonia Linn. (Begoniaceae) in karst regions from Guizhou, China 期刊论文
PHYTOTAXA, 2019, 卷号: 409, 期号: 1, 页码: 49-52
作者:  He, Shun-Zhi;  Guo, Shi-Wei;  Chen, Wen-Hong;  Zhang, Rong-Mei;  Shui, Yu-Min
浏览  |  Adobe PDF(644Kb)  |  收藏  |  浏览/下载:255/42  |  提交时间:2019/08/19
Begoniaceae  Begonia  Guizhou  new species  geophyte  
长柱重楼总皂苷体外抗肿瘤活性及毒性研究 期刊论文
中国临床药理学杂志, 2018, 卷号: 034, 期号: 004, 页码: 439
作者:  杨蓉蓉;  王跃虎;  施敏;  陈雪梅;  陈英杰;  王鹏;  周轶平
收藏  |  浏览/下载:119/0  |  提交时间:2018/11/26
Protostane-Type Triterpenoids from Alisma orientale 期刊论文
CHEMISTRY & BIODIVERSITY, 2017, 卷号: 14, 期号: 12, 页码: e1700452
作者:  Li, Hong-Mei;  Chen, Xue-Jiao;  Luo, Dan;  Fan, Min;  Zhang, Zhi-Jun;  Peng, Li-Yan;  Wu, Xing-De;  Li, Rong-Tao;  Ji, Xu;  Zhao, Qin-Shi
收藏  |  浏览/下载:282/0  |  提交时间:2018/05/08
Alisma Orientale  Alismatis Rhizoma  Alismataceae  Protostane Triterpenoids  Vasorelaxant Activity  
长柱重楼总皂苷的抗肿瘤活性及急性毒性作用研究 期刊论文
药物评价研究, 2017, 卷号: 40, 期号: 07, 页码: 904-910
作者:  陈雪梅;  杨焕芝;  施敏;  杨蓉蓉;  陈英杰;  王跃虎;  周轶平
收藏  |  浏览/下载:197/0  |  提交时间:2018/08/21
长柱重楼  总皂苷  抗肿瘤  小鼠肝癌  急性毒性  脏器系数